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Variable selection problem for the nonlinear Cox regression model is considered. In survival analysis, one main objective is to identify the covariates that are associated with the risk of experiencing the event of interest. The Cox…

机器学习 · 统计学 2022-11-18 Kexuan Li

The Cox proportional hazards model is a canonical method in survival analysis for prediction of the life expectancy of a patient given clinical or genetic covariates -- it is a linear model in its original form. In recent years, several…

The tuning parameter selection strategy for penalized estimation is crucial to identify a model that is both interpretable and predictive. However, popular strategies (e.g., minimizing average squared prediction error via cross-validation)…

统计方法学 · 统计学 2022-11-10 Julia Holter , Jonathan Stallrich

We study the Cox models with semiparametric relative risk, which can be partially linear with one nonparametric component, or multiple additive or nonadditive nonparametric components. A penalized partial likelihood procedure is proposed to…

统计理论 · 数学 2010-10-20 Pang Du , Shuangge Ma , Hua Liang

The use of massive survival data has become common in survival analysis. In this study, a subsampling algorithm is proposed for the Cox proportional hazards model with time-dependent covariates when the sample is extraordinarily large but…

统计计算 · 统计学 2023-02-07 Nan Qiao , Wangcheng Li , Feng Xiao , Cunjie Lin , Yong Zhou

Cross validation is commonly used for selecting tuning parameters in penalized regression, but its use in penalized Cox regression models has received relatively little attention in the literature. Due to its partial likelihood…

统计方法学 · 统计学 2026-05-13 Biyue Dai , Patrick Breheny

In high-dimensional survival analysis, effective variable selection is crucial for both model interpretation and predictive performance. This paper investigates Cox regression with lasso and adaptive lasso penalties in genomic datasets…

统计方法学 · 统计学 2025-07-02 Pilar González-Barquero , Rosa E. Lillo , Álvaro Méndez-Civieta

The purpose of this article is to provide an adaptive estimator of the baseline function in the Cox model with high-dimensional covariates. We consider a two-step procedure : first, we estimate the regression parameter of the Cox model via…

统计理论 · 数学 2015-03-04 Agathe Guilloux , Sarah Lemler , Marie-Luce Taupin

In this paper, we explore a method for treating survival analysis as a classification problem. The method uses a "stacking" idea that collects the features and outcomes of the survival data in a large data frame, and then treats it as a…

统计方法学 · 统计学 2019-09-27 Chenyang Zhong , Robert Tibshirani

We study the variable selection problem in survival analysis to identify the most important factors affecting survival time. Our method incorporates prior knowledge of mutual correlations among variables, represented through a graph. We…

统计理论 · 数学 2025-04-25 Liyan Xie , Xi He , Pinar Keskinocak , Yao Xie

Survival analysis is a widely used statistical framework for modeling time-to-event data under censoring. Classical methods, such as the Cox proportional hazards (Cox PH) model, offer a semiparametric approach to estimating the effects of…

机器学习 · 统计学 2026-04-23 Yang Xu , Wenbin Lu , Rui Song

While there are many well-developed data science methods for classification and regression, there are relatively few methods for working with right-censored data. Here, we present "survival stacking": a method for casting survival analysis…

统计方法学 · 统计学 2021-07-29 Erin Craig , Chenyang Zhong , Robert Tibshirani

In a Gaussian graphical model, the conditional independence between two variables are characterized by the corresponding zero entries in the inverse covariance matrix. Maximum likelihood method using the smoothly clipped absolute deviation…

统计方法学 · 统计学 2009-09-07 Xin Gao , Daniel Q. Pu , Yuehua Wu , Hong Xu

Modern variable selection procedures make use of penalization methods to execute simultaneous model selection and estimation. A popular method is the LASSO (least absolute shrinkage and selection operator), the use of which requires…

统计方法学 · 统计学 2023-01-12 Meadhbh O'Neill , Kevin Burke

Survival analysis is a challenging variation of regression modeling because of the presence of censoring, where the outcome measurement is only partially known, due to, for example, loss to follow up. Such problems come up frequently in…

机器学习 · 计算机科学 2022-06-28 Chirag Nagpal , Steve Yadlowsky , Negar Rostamzadeh , Katherine Heller

Variable selection in high dimensional space has challenged many contemporary statistical problems from many frontiers of scientific disciplines. Recent technology advance has made it possible to collect a huge amount of covariate…

机器学习 · 统计学 2010-05-20 Jianqing Fan , Yang Feng , Yichao Wu

In this work a method to regularize Cox frailty models is proposed that accommodates time-varying covariates and time-varying coefficients and is based on the full instead of the partial likelihood. A particular advantage in this framework…

统计方法学 · 统计学 2020-04-01 Maike Hohberg , Andreas Groll

We consider the finite sample properties of the regularized high-dimensional Cox regression via lasso. Existing literature focuses on linear models or generalized linear models with Lipschitz loss functions, where the empirical risk…

统计理论 · 数学 2012-04-11 Shengchun Kong , Bin Nan

In this paper, for Lasso penalized linear regression models in high-dimensional settings, we propose a modified cross-validation method for selecting the penalty parameter. The methodology is extended to other penalties, such as Elastic…

统计方法学 · 统计学 2013-09-10 Yi Yu , Yang Feng

We introduce a pliable lasso method for estimation of interaction effects in the Cox proportional hazards model framework. The pliable lasso is a linear model that includes interactions between covariates X and a set of modifying variables…

应用统计 · 统计学 2018-07-19 Wenfei Du , Rob Tibshirani
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