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We propose a counterfactual approach to train ``causality-aware" predictive models that are able to leverage causal information in static anticausal machine learning tasks (i.e., prediction tasks where the outcome influences the features).…

应用统计 · 统计学 2020-12-01 Elias Chaibub Neto

Meta-analysis, by synthesizing effect estimates from multiple studies conducted in diverse settings, stands at the top of the evidence hierarchy in clinical research. Yet, conventional approaches based on fixed- or random-effects models…

Missingness in variables that define study eligibility criteria is a seldom addressed challenge in electronic health record (EHR)-based settings. It is typically the case that patients with incomplete eligibility information are excluded…

Discovering causal effects is at the core of scientific investigation but remains challenging when only observational data is available. In practice, causal networks are difficult to learn and interpret, and limited to relatively small…

Time series data are found in many areas of healthcare such as medical time series, electronic health records (EHR), measurements of vitals, and wearable devices. Causal discovery, which involves estimating causal relationships from…

机器学习 · 计算机科学 2023-10-18 Muhammad Hasan Ferdous , Uzma Hasan , Md Osman Gani

How does a cause lead to an effect, and which intermediate causal steps explain their connection? This work scrutinizes the mechanistic causal reasoning capabilities of large language models (LLMs) to answer these questions through the task…

人工智能 · 计算机科学 2026-03-19 Liesbeth Allein , Nataly Pineda-Castañeda , Andrea Rocci , Marie-Francine Moens

We develop a method for generating causal post-hoc explanations of black-box classifiers based on a learned low-dimensional representation of the data. The explanation is causal in the sense that changing learned latent factors produces a…

机器学习 · 计算机科学 2020-10-23 Matthew O'Shaughnessy , Gregory Canal , Marissa Connor , Mark Davenport , Christopher Rozell

While many areas of machine learning have benefited from the increasing availability of large and varied datasets, the benefit to causal inference has been limited given the strong assumptions needed to ensure identifiability of causal…

机器学习 · 计算机科学 2022-01-02 Wenshuo Guo , Serena Wang , Peng Ding , Yixin Wang , Michael I. Jordan

Directed Acyclic Graphs (DAGs) are a standard tool in causal modeling, but their suitability for capturing the complexity of large-scale multimodal data is questionable. In practice, real-world multimodal datasets are often collected from…

Learning representations purely from observations concerns the problem of learning a low-dimensional, compact representation which is beneficial to prediction models. Under the hypothesis that the intrinsic latent factors follow some casual…

机器学习 · 计算机科学 2023-10-24 Mengyue Yang , Xinyu Cai , Furui Liu , Weinan Zhang , Jun Wang

Missing data arise in most applied settings and are ubiquitous in electronic health records (EHR). When data are missing not at random (MNAR) with respect to measured covariates, sensitivity analyses are often considered. These post-hoc…

统计方法学 · 统计学 2023-07-11 Alexander W. Levis , Rajarshi Mukherjee , Rui Wang , Heidi Fischer , Sebastien Haneuse

Healthcare is becoming a more and more important research topic recently. With the growing data in the healthcare domain, it offers a great opportunity for deep learning to improve the quality of medical service. However, the complexity of…

计算与语言 · 计算机科学 2021-11-01 Bo Yang , Lijun Wu

Causal inference from electronic health records (EHR) is fundamentally limited by unmeasured confounding: critical clinical states such as frailty, goals of care, and mental status are documented in free-text notes but absent from…

机器学习 · 计算机科学 2026-04-22 Lei Liu , Jialin Chen , Kathy Macropol

Estimating causal effects from nonexperimental data is a fundamental problem in many fields of science. A key component of this task is selecting an appropriate set of covariates for confounding adjustment to avoid bias. Most existing…

机器学习 · 计算机科学 2025-10-28 Zheng Li , Xichen Guo , Feng Xie , Yan Zeng , Hao Zhang , Zhi Geng

The machine learning community has recently devoted much attention to the problem of inferring causal relationships from statistical data. Most of this work has focused on uncovering connections among scalar random variables. We generalize…

机器学习 · 统计学 2012-07-10 Doris Entner , Patrik O. Hoyer

Causality is a fundamental part of the scientific endeavour to understand the world. Unfortunately, causality is still taboo in much of psychology and social science. Motivated by a growing number of recommendations for the importance of…

统计方法学 · 统计学 2022-06-27 Matthew J. Vowels

The investigation of the question "which treatment has a causal effect on a target variable?" is of particular relevance in a large number of scientific disciplines. This challenging task becomes even more difficult if not all treatment…

统计方法学 · 统计学 2022-02-28 Sergio Hernan Garrido Mejia , Elke Kirschbaum , Dominik Janzing

Target trial emulation (TTE) enables causal questions to be studied with observational data when randomized controlled trials (RCTs) are infeasible. Yet treatment-effect methods often address causal estimation, missingness, and temporal…

Causality is vital for understanding true cause-and-effect relationships between variables within predictive models, rather than relying on mere correlations, making it highly relevant in the field of Explainable AI. In an automated…

机器学习 · 计算机科学 2024-08-28 Arturo Fredes , Jordi Vitria

We develop new methods to integrate experimental and observational data in causal inference. While randomized controlled trials offer strong internal validity, they are often costly and therefore limited in sample size. Observational data,…

计量经济学 · 经济学 2025-11-04 Xuelin Yang , Licong Lin , Susan Athey , Michael I. Jordan , Guido W. Imbens