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Robots that interact with humans must adapt to individual users' preferences to operate effectively in human-centered environments. An intuitive and effective technique to learn non-expert users' preferences is through rankings of robot…

机器人学 · 计算机科学 2026-03-11 Nathaniel Dennler , Zhonghao Shi , Yiran Tao , Andreea Bobu , Stefanos Nikolaidis , Maja Matarić

Predicting and discovering drug-drug interactions (DDIs) using machine learning has been studied extensively. However, most of the approaches have focused on text data or textual representation of the drug structures. We present the first…

机器学习 · 计算机科学 2021-03-22 Devendra Singh Dhami , Siwen Yan , Gautam Kunapuli , David Page , Sriraam Natarajan

Predicting drug-target interaction is key for drug discovery. Recent deep learning-based methods show promising performance but two challenges remain: (i) how to explicitly model and learn local interactions between drugs and targets for…

机器学习 · 计算机科学 2023-01-23 Peizhen Bai , Filip Miljković , Bino John , Haiping Lu

Deep heteroscedastic regression involves jointly optimizing the mean and covariance of the predicted distribution using the negative log-likelihood. However, recent works show that this may result in sub-optimal convergence due to the…

机器学习 · 计算机科学 2024-06-03 Megh Shukla , Mathieu Salzmann , Alexandre Alahi

Advancements in large language models (LLMs) allow them to address diverse questions using human-like interfaces. Still, limitations in their training prevent them from answering accurately in scenarios that could benefit from multiple…

人工智能 · 计算机科学 2025-04-09 Yoshitaka Inoue , Tianci Song , Xinling Wang , Augustin Luna , Tianfan Fu

Drug-drug interactions (DDIs) are a major concern in clinical practice, as they can lead to reduced therapeutic efficacy or severe adverse effects. Traditional computational approaches often struggle to capture the complex relationships…

机器学习 · 计算机科学 2025-08-27 Hongbo Liu , Siyi Li , Zheng Yu

An important problem in the field of bioinformatics is to identify interactive effects among profiled variables for outcome prediction. In this paper, a logistic regression model with pairwise interactions among a set of binary covariates…

人工智能 · 计算机科学 2016-12-30 Easton Li Xu , Xiaoning Qian , Tie Liu , Shuguang Cui

Predicting drug-target interaction (DTI) is critical in the drug discovery process. Despite remarkable advances in recent DTI models through the integration of representations from diverse drug and target encoders, such models often…

定量方法 · 定量生物学 2025-09-30 Zhaohan Meng , Zaiqiao Meng , Ke Yuan , Iadh Ounis

Clinical trials are crucial for drug development but are time consuming, expensive, and often burdensome on patients. More importantly, clinical trials face uncertain outcomes due to issues with efficacy, safety, or problems with patient…

计算机与社会 · 计算机科学 2022-03-15 Tianfan Fu , Kexin Huang , Cao Xiao , Lucas M. Glass , Jimeng Sun

Deep learning models have demonstrated exceptional performance across a wide range of computer vision tasks. However, their performance often degrades significantly when faced with distribution shifts, such as domain or dataset changes.…

计算机视觉与模式识别 · 计算机科学 2025-07-09 Samuel Barbeau , Pedram Fekri , David Osowiechi , Ali Bahri , Moslem Yazdanpanah , Masih Aminbeidokhti , Christian Desrosiers

Assessing drug-target affinity is a critical step in the drug discovery and development process, but to obtain such data experimentally is both time consuming and expensive. For this reason, computational methods for predicting binding…

机器学习 · 计算机科学 2022-09-15 Elizaveta Vinogradova , Karina Pats , Ferdinand Molnár , Siamac Fazli

Many existing unsupervised domain adaptation (UDA) methods primarily focus on covariate shift, limiting their effectiveness in imbalanced domain adaptation (IDA) where both covariate shift and label shift coexist. Recent IDA methods have…

计算机视觉与模式识别 · 计算机科学 2024-12-31 Xiaona Sun , Zhenyu Wu , Zhiqiang Zhan , Yang Ji

Independent Component Analysis (ICA) is a dimensionality reduction technique that can boost efficiency of machine learning models that deal with probability density functions, e.g. Bayesian neural networks. Algorithms that implement…

机器学习 · 计算机科学 2017-07-10 Mahdi Nazemi , Shahin Nazarian , Massoud Pedram

Token-based transformer world models have shown strong performance in visual reinforcement learning, but often suffer from temporal inconsistency in long-horizon rollouts, including object duplication, disappearance, and transmutation. A…

机器学习 · 计算机科学 2026-05-27 Youngin Kim , Ray Sun , Inho Kim , Bumsoo Park , Hyun Oh Song

This paper proposes joint attention estimation in a single image. Different from related work in which only the gaze-related attributes of people are independently employed, (I) their locations and actions are also employed as contextual…

计算机视觉与模式识别 · 计算机科学 2023-08-11 Chihiro Nakatani , Hiroaki Kawashima , Norimichi Ukita

We investigate the possibility of an incentive-compatible (IC, a.k.a. strategy-proof) mechanism for the classification of agents in a network according to their reviews of each other. In the $ \alpha $-classification problem we are…

计算机科学与博弈论 · 计算机科学 2019-11-21 Yakov Babichenko , Oren Dean , Moshe Tennenholtz

Click-through rate (CTR) Prediction is a crucial task in personalized information retrievals, such as industrial recommender systems, online advertising, and web search. Most existing CTR Prediction models utilize explicit feature…

信息检索 · 计算机科学 2024-02-19 Honghao Li , Lei Sang , Yi Zhang , Xuyun Zhang , Yiwen Zhang

Although attention mechanisms have been applied to a variety of deep learning models and have been shown to improve the prediction performance, it has been reported to be vulnerable to perturbations to the mechanism. To overcome the…

计算与语言 · 计算机科学 2022-11-23 Shunsuke Kitada , Hitoshi Iyatomi

This work studies the problem of inferring whether an agent is directly influenced by another agent over an adaptive diffusion network. Agent i influences agent j if they are connected (according to the network topology), and if agent j…

多智能体系统 · 计算机科学 2017-07-21 Vincenzo Matta , Ali H. Sayed

Context: Indirect treatment comparisons (ITC) are essential when direct head-to-head evidence is unavailable. Their reliability depends on rigorous methodological choices and careful assessment of underlying assumptions. Appropriate…

统计方法学 · 统计学 2026-05-12 Louise Baschet , Ana Jarne , Matthias Monnereau , Clémence Fradet , Axel Benoist