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Large Language Models (LLMs) have demonstrated significant potential in medical Question Answering (QA), yet they remain prone to hallucinations and ungrounded reasoning, limiting their reliability in high-stakes clinical scenarios. While…

信息检索 · 计算机科学 2026-01-09 Jessica Ryan , Alexander I. Gumilang , Robert Wiliam , Derwin Suhartono

Reliable Large Language Models (LLMs) should abstain when confidence is insufficient. However, prior studies often treat refusal as a generic "I don't know'', failing to distinguish input-level ambiguity (data uncertainty) from capability…

计算与语言 · 计算机科学 2026-04-21 Jingyi Ren , Ante Wang , Yunghwei Lai , Xiaolong Wang , Linlu Gong , Weitao Li , Weizhi Ma , Yang Liu

Large Language Models (LLMs) demonstrate strong reasoning performance, yet their ability to reliably monitor, diagnose, and correct their own errors remains limited. We introduce a psychologically grounded metacognitive framework that…

计算与语言 · 计算机科学 2026-02-24 Abraham Paul Elenjical , Vivek Hruday Kavuri , Vasudeva Varma

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

计算与语言 · 计算机科学 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li

Large Language Models (LLMs) have demonstrated exceptional capabilities, yet selecting the most reliable response from multiple LLMs remains a challenge, particularly in resource-constrained settings. Existing approaches often depend on…

Reliable uncertainty quantification (UQ) is essential when employing large language models (LLMs) in high-risk domains such as clinical question answering (QA). In this work, we evaluate uncertainty estimation methods for clinical QA…

计算与语言 · 计算机科学 2026-01-27 Alberto Testoni , Iacer Calixto

With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…

人工智能 · 计算机科学 2025-12-29 Zelin Zang , Wenyi Gu , Siqi Ma , Dan Yang , Yue Shen , Zhu Zhang , Guohui Fan , Wing-Kuen Ling , Fuji Yang

Medical reasoning in large language models (LLMs) aims to emulate clinicians' diagnostic thinking, but current benchmarks such as MedQA-USMLE, MedMCQA, and PubMedQA often mix reasoning with factual recall. We address this by separating 11…

Despite the rapid expansion of Large Language Models (LLMs) in healthcare, robust and explainable evaluation of their ability to assess clinical trial reporting according to CONSORT standards remains an open challenge. In particular,…

人工智能 · 计算机科学 2026-02-26 Sohyeon Jeon , Hyung-Chul Lee

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

计算与语言 · 计算机科学 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Large language models (LLMs) have demonstrated strong capabilities in complex reasoning tasks, yet their decision-making processes remain difficult to interpret. Existing explanation methods often lack trustworthy structural insight and are…

机器学习 · 计算机科学 2026-02-24 Yujiao Yang

Advances in large language models (LLMs) have encouraged their adoption in the healthcare domain where vital clinical information is often contained in unstructured notes. Cancer staging status is available in clinical reports, but it…

计算与语言 · 计算机科学 2024-08-30 Chia-Hsuan Chang , Mary M. Lucas , Yeawon Lee , Christopher C. Yang , Grace Lu-Yao

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

计算与语言 · 计算机科学 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Multimodal Large Language Models (MLLMs) have tremendous potential to improve the accuracy, availability, and cost-effectiveness of healthcare by providing automated solutions or serving as aids to medical professionals. Despite promising…

计算机视觉与模式识别 · 计算机科学 2025-05-22 Mohammad Shahab Sepehri , Zalan Fabian , Maryam Soltanolkotabi , Mahdi Soltanolkotabi

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face…

计算与语言 · 计算机科学 2025-01-22 Hang Yang , Hao Chen , Hui Guo , Yineng Chen , Ching-Sheng Lin , Shu Hu , Jinrong Hu , Xi Wu , Xin Wang

Large Language Models suffer from hallucination, generating plausible yet factually incorrect content. Current mitigation strategies focus on post-generation correction, which is computationally expensive and fails to prevent unreliable…

计算与语言 · 计算机科学 2025-10-03 Nandakishor M

This paper presents the overview of the development and fine-tuning of large language models (LLMs) designed specifically for answering medical questions. We are mainly improving the accuracy and efficiency of providing reliable answers to…

计算与语言 · 计算机科学 2025-01-30 Aysegul Ucar , Soumik Nayak , Anunak Roy , Burak Taşcı , Gülay Taşcı

To enhance Large Language Models' (LLMs) reliability, calibration is essential -- the model's assessed confidence scores should align with the actual likelihood of its responses being correct. However, current confidence elicitation methods…

计算与语言 · 计算机科学 2024-10-29 Yukun Huang , Yixin Liu , Raghuveer Thirukovalluru , Arman Cohan , Bhuwan Dhingra

User profiling, as a core technique for user understanding, aims to infer structural attributes from user information. Large Language Models (LLMs) provide a promising avenue for user profiling, yet the progress is hindered by the lack of…

人工智能 · 计算机科学 2025-09-24 Yingxin Li , Jianbo Zhao , Xueyu Ren , Jie Tang , Wangjie You , Xu Chen , Kan Zhou , Chao Feng , Jiao Ran , Yuan Meng , Zhi Wang

While recent large language models (LLMs) improve on various question answering (QA) datasets, it remains difficult for a single model to generalize across question types that require distinct reasoning abilities. We provide empirical…

计算与语言 · 计算机科学 2023-10-23 Chenglei Si , Weijia Shi , Chen Zhao , Luke Zettlemoyer , Jordan Boyd-Graber