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Empowered by vast internal knowledge reservoir, the new generation of large language models (LLMs) demonstrate untapped potential to tackle medical tasks. However, there is insufficient effort made towards summoning up a synergic effect…

计算与语言 · 计算机科学 2025-05-23 Kexin Shang , Chia-Hsuan Chang , Christopher C. Yang

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

计算与语言 · 计算机科学 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

Biomedical question answering often requires decisions from retrieved literature whose relevance, quality, and support for candidate answers are uneven. Most retrieval-augmented large language model (LLM) methods feed this literature to the…

计算与语言 · 计算机科学 2026-05-19 Chang Zong , Hao Ning , Siliang Tang , Jie Huang , Jian Wan

Large language models (LLMs) achieve strong reasoning performance through chain-of-thought (CoT) reasoning, yet often generate unnecessarily long reasoning paths that incur high inference cost. Recent self-consistency-based approaches…

计算与语言 · 计算机科学 2026-03-19 Juming Xiong , Kevin Guo , Congning Ni , Chao Yan , Katherine Brown , Avinash Baidya , Xiang Gao , Bradley Malin , Zhijun Yin

While large language models (LLMs) have shown to perform well on monolingual mathematical and commonsense reasoning, they remain unreliable for multilingual medical reasoning applications, hindering their deployment in multilingual…

人工智能 · 计算机科学 2026-04-28 Eric Onyame , Akash Ghosh , Subhadip Baidya , Sriparna Saha , Xiuying Chen , Chirag Agarwal

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

计算与语言 · 计算机科学 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

计算与语言 · 计算机科学 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu

Trustworthiness in healthcare question-answering (QA) systems is important for ensuring patient safety, clinical effectiveness, and user confidence. As large language models (LLMs) become increasingly integrated into medical settings, the…

计算与语言 · 计算机科学 2025-11-04 Yinuo Wang , Baiyang Wang , Robert E. Mercer , Frank Rudzicz , Sudipta Singha Roy , Pengjie Ren , Zhumin Chen , Xindi Wang

Medical question-answering (QA) is a critical task for evaluating how effectively large language models (LLMs) encode clinical knowledge and assessing their potential applications in medicine. Despite showing promise on multiple-choice…

计算与语言 · 计算机科学 2025-03-06 Guangfu Guo , Kai Zhang , Bryan Hoo , Yujun Cai , Xiaoqian Lu , Nanyun Peng , Yiwei Wang

Multimodal large language models (MLLMs) demonstrate considerable potential in clinical diagnostics, a domain that inherently requires synthesizing complex visual and textual data alongside consulting authoritative medical literature.…

计算与语言 · 计算机科学 2026-03-23 Yannian Gu , Zhongzhen Huang , Linjie Mu , Xizhuo Zhang , Shaoting Zhang , Xiaofan Zhang

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

计算与语言 · 计算机科学 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

The deployment of Large Language Models in Medical Question Answering is severely hampered by ambiguous user queries, a significant safety risk that demonstrably reduces answer accuracy in high-stakes healthcare settings. In this paper, we…

计算与语言 · 计算机科学 2026-01-27 Yaokun Liu , Yifan Liu , Phoebe Mbuvi , Zelin Li , Ruichen Yao , Gawon Lim , Dong Wang

This study investigates uncertainty quantification in large language models (LLMs) for medical applications, emphasizing both technical innovations and philosophical implications. As LLMs become integral to clinical decision-making,…

Large Language Models (LLMs) have shown significant advances in text generation but often lack the reliability needed for autonomous deployment in high-stakes domains like healthcare, law, and finance. Existing approaches rely on external…

人工智能 · 计算机科学 2024-11-12 Ninad Naik

Large Language Models (LLMs) have achieved high accuracy on medical question-answer (QA) benchmarks, yet their capacity for flexible clinical reasoning has been debated. Here, we asked whether advances in reasoning LLMs improve their…

计算与语言 · 计算机科学 2026-01-21 Kie Shidara , Preethi Prem , Jonathan Kim , Anna Podlasek , Feng Liu , Ahmed Alaa , Danilo Bernardo

We introduce a new approach in which several advanced large language models-specifically GPT-4-0125-preview, Meta-LLAMA-3-70B-Instruct, Claude-3-Opus, and Gemini-1.5-Flash-collaborate to both produce and answer intricate, doctoral-level…

Incorporating large language models (LLMs) in medical question answering demands more than high average accuracy: a model that returns substantively different answers each time it is queried is not a reliable medical tool. Online health…

信息检索 · 计算机科学 2026-04-14 Avi-ad Avraam Buskila

Large language models (LLMs) achieve strong average performance yet remain unreliable at the instance level, with frequent hallucinations, brittle failures, and poorly calibrated confidence. We study reliability through the lens of…

人工智能 · 计算机科学 2026-01-13 Pranav Kallem

Medical Question-Answering (QA) encompasses a broad spectrum of tasks, including multiple choice questions (MCQ), open-ended text generation, and complex computational reasoning. Despite this variety, a unified framework for delivering…

计算与语言 · 计算机科学 2025-06-23 Xiaotian Zhang , Yuan Wang , Zhaopeng Feng , Ruizhe Chen , Zhijie Zhou , Yan Zhang , Hongxia Xu , Jian Wu , Zuozhu Liu

The potential of Multimodal Large Language Models (MLLMs) in domain of medical imaging raise the demands of systematic and rigorous evaluation frameworks that are aligned with the real-world medical imaging practice. Existing practices that…

计算与语言 · 计算机科学 2026-04-16 Zhijie Bao , Fangke Chen , Licheng Bao , Chenhui Zhang , Wei Chen , Jiajie Peng , Zhongyu Wei
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