相关论文: Interpretable Machine Learning for Cognitive Aging…
Alzheimer's disease (AD), a degenerative brain condition, can benefit from early prediction to slow its progression. As the disease progresses, patients typically undergo brain atrophy. Current prediction methods for Alzheimers disease…
Alzheimer's Disease (AD) early detection is critical for enabling timely intervention and improving patient outcomes. This paper presents a DMV framework using Llama3-70B and GPT-4o as embedding models to analyze clinical notes and predict…
Background: Elderly patients with MODS have high risk of death and poor prognosis. The performance of current scoring systems assessing the severity of MODS and its mortality remains unsatisfactory. This study aims to develop an…
Alzheimer's disease (AD) is an irreversible devastative neurodegenerative disorder associated with progressive impairment of memory and cognitive functions. Its early diagnosis is crucial for the development of possible future treatment…
Early detection of Alzheimer's disease (AD) requires models capable of integrating macro-scale neuroanatomical alterations with micro-scale genetic susceptibility, yet existing multimodal approaches struggle to align these heterogeneous…
Social Determinants of Health (SDOH) refer to environmental, behavioral, and social conditions that influence how individuals live, work, and age. SDOH have a significant impact on personal health outcomes, and their systematic…
Objective: The n2c2/UW SDOH Challenge explores the extraction of social determinant of health (SDOH) information from clinical notes. The objectives include the advancement of natural language processing (NLP) information extraction…
Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the leading cause of dementia, significantly impacting cost, mortality, and burden worldwide. The advent of high-throughput omics technologies, such as genomics,…
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia, affecting memory, reasoning, communication, and daily functioning. Early diagnosis is particularly important, as timely intervention may…
The timely identification of significant memory concern (SMC) is crucial for proactive cognitive health management, especially in an aging population. Detecting SMC early enables timely intervention and personalized care, potentially…
We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…
Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…
The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…
Objective: this study has a twofold goal. First, it aims to improve the understanding of the impact of Dementia of type Alzheimer's Disease (AD) on different aspects of the lexicon. Second, it aims to demonstrate that such aspects of the…
Alzheimer's disease (AD) is a progressive neurological disorder, meaning that the symptoms develop gradually throughout the years. It is also the main cause of dementia, which affects memory, thinking skills, and mental abilities. Nowadays,…
Alzheimer's disease (AD) is an irreversible brain disease that can dramatically reduce quality of life, most commonly manifesting in older adults and eventually leading to the need for full-time care. Early detection is fundamental to…
In computational neuroscience, there has been an increased interest in developing machine learning algorithms that leverage brain imaging data to provide estimates of "brain age" for an individual. Importantly, the discordance between brain…
Understanding the relationship between cognition and intrinsic brain activity through purely data-driven approaches remains a significant challenge in neuroscience. Resting-state functional magnetic resonance imaging (rs-fMRI) offers a…
With the global population aging rapidly, Alzheimer's disease (AD) is particularly prominent in older adults, which has an insidious onset and leads to a gradual, irreversible deterioration in cognitive domains (memory, communication,…
Introduction: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia. Methods: A deep learning method is…