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Speech-based automatic detection of Alzheimer's disease (AD) and depression has attracted increased attention. Confidence estimation is crucial for a trust-worthy automatic diagnostic system which informs the clinician about the confidence…

计算与语言 · 计算机科学 2024-09-10 Wen Wu , Chao Zhang , Philip C. Woodland

The evolution of deep learning and artificial intelligence has significantly reshaped technological landscapes. However, their effective application in crucial sectors such as medicine demands more than just superior performance, but…

计算机视觉与模式识别 · 计算机科学 2024-02-27 Yasmine Mustafa , Tie Luo

Alzheimer's Disease (AD) is a progressive neurological disorder that can result in significant cognitive impairment and dementia. Accurate and timely diagnosis is essential for effective treatment and management of this disease. In this…

图像与视频处理 · 电气工程与系统科学 2024-12-10 Mozhgan Naderi , Maryam Rastgarpour , Amir Reza Takhsha

We model Alzheimer's disease (AD) progression by combining differential equations (DEs) and reinforcement learning (RL) with domain knowledge. DEs provide relationships between some, but not all, factors relevant to AD. We assume that the…

Alzheimer's disease (AD) is a progressive neurodegenerative disease with high inter-patient variance in rate of cognitive decline. AD progression prediction aims to forecast patient cognitive decline and benefits from incorporating multiple…

机器学习 · 计算机科学 2025-09-17 Benjamin Burns , Yuan Xue , Douglas W. Scharre , Xia Ning

This paper explores deterioration in Alzheimers Disease using Machine Learning. Subjects were split into two datasets based on baseline diagnosis (Cognitively Normal, Mild Cognitive Impairment), with outcome of deterioration at final visit…

机器学习 · 计算机科学 2023-06-21 Henry Musto , Daniel Stamate , Ida Pu , Daniel Stahl

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

图像与视频处理 · 电气工程与系统科学 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

Depression commonly co-occurs with neurodegenerative disorders like Multiple Sclerosis (MS), yet the potential of speech-based Artificial Intelligence for detecting depression in such contexts remains unexplored. This study examines the…

The need for an intelligent, real-time spoilage prediction system has become critical in modern IoT-driven food supply chains, where perishable goods are highly susceptible to environmental conditions. Existing methods often lack…

Accurate and early diagnosis of Alzheimer's disease (AD) is critical for effective intervention and requires integrating complementary information from multimodal neuroimaging data. However, conventional fusion approaches often rely on…

The aging society urgently requires scalable methods to monitor cognitive decline and identify social and psychological factors indicative of dementia risk in older adults. Our machine learning (ML) models captured facial, acoustic,…

Individualized Alzheimer's disease (AD) progression prediction requires models that use irregular visits, account for censoring, avoid diagnostic leakage, and provide calibrated horizon risks. We propose PROgression-aware MultI-horizon…

机器学习 · 计算机科学 2026-05-01 Qing Lyu , Jeremy Hudson , Mohammad Kawas , Yuming Jiang , Chenyu You , Christopher T Whitlow

Healthcare datasets present many challenges to both machine learning and statistics as their data are typically heterogeneous, censored, high-dimensional and have missing information. Feature selection is often used to identify the…

机器学习 · 计算机科学 2022-07-06 Annette Spooner , Gelareh Mohammadi , Perminder S. Sachdev , Henry Brodaty , Arcot Sowmya

Alzheimer's disease (AD) develops over a prolonged preclinical phase, during which neuropathological changes accumulate long before cognitive symptoms appear. Identifying cognitive functions affected at early stages is critical for the…

Alzheimer's Disease (AD) detection employs machine learning classification models to distinguish between individuals with AD and those without. Different from conventional classification tasks, we identify within-class variation as a…

音频与语音处理 · 电气工程与系统科学 2025-09-29 Jiawen Kang , Dongrui Han , Lingwei Meng , Jingyan Zhou , Jinchao Li , Xixin Wu , Helen Meng

Mild Cognitive Impairment (MCI) is an early stage of Alzheimer's disease (AD), a form of neurodegenerative disorder. Early identification of MCI is crucial for delaying its progression through timely interventions. Existing research has…

音频与语音处理 · 电气工程与系统科学 2024-10-18 Kristin Qi , Jiatong Shi , Caroline Summerour , John A. Batsis , Xiaohui Liang

Disease modifying therapies for Alzheimer's disease demand precise timing decisions, yet current predictive models require longitudinal observations and provide no uncertainty quantification, rendering them impractical at the critical first…

机器学习 · 计算机科学 2026-04-13 Alireza Moayedikia , Sara Fin , Uffe Kock Wiil

Alzheimer's disease (AD) is a neurodegenerative disorder with no known cure that affects tens of millions of people worldwide. Early detection of AD is critical for timely intervention to halt or slow the progression of the disease. In this…

机器学习 · 计算机科学 2025-07-08 Mahdi Moghaddami , Clayton Schubring , Mohammad-Reza Siadat

Alzheimer's disease (AD) is a progressive brain disorder that causes memory and functional impairments. The advances in machine learning and publicly available medical datasets initiated multiple studies in AD diagnosis. In this work, we…

图像与视频处理 · 电气工程与系统科学 2021-07-20 Aidana Massalimova , Huseyin Atakan Varol

Alzheimer's disease (AD) dementia is the most common form of dementia. With the emergence of disease-modifying therapies, predicting disease risk before symptom onset has become critical. We introduce DuAL-Net, a hybrid deep learning…

基因组学 · 定量生物学 2025-06-03 Eun Hye Lee , Taeho Jo
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