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Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Clinical diagnosis begins with doctor-patient interaction, during which physicians iteratively gather information, determine examination and refine differential diagnosis through patients' response. This dynamic clinical-reasoning process…

计算与语言 · 计算机科学 2025-12-30 Yuqi Tang , Jing Yu , Zichang Su , Kehua Feng , Zhihui Zhu , Libin Wang , Lei Liang , Qiang Zhang , Keyan Ding , Huajun Chen

The deployment of Large Language Models (LLMs) in high-stakes clinical settings demands rigorous and reliable evaluation. However, existing medical benchmarks remain static, suffering from two critical limitations: (1) data contamination,…

人工智能 · 计算机科学 2026-02-12 Zhiling Yan , Dingjie Song , Zhe Fang , Yisheng Ji , Xiang Li , Quanzheng Li , Lichao Sun

Large language models (LLMs) have demonstrated promising performance on medical benchmarks; however, their ability to perform medical calculations, a crucial aspect of clinical decision-making, remains underexplored and poorly evaluated.…

计算与语言 · 计算机科学 2026-02-03 Benlu Wang , Iris Xia , Yifan Zhang , Junda Wang , Feiyun Ouyang , Shuo Han , Arman Cohan , Hong Yu , Zonghai Yao

The rapid progress of multimodal large language models (MLLMs) calls for more reliable evaluation protocols. Existing static benchmarks suffer from the potential risk of data contamination and saturation, leading to inflated or misleading…

计算机视觉与模式识别 · 计算机科学 2026-01-22 Junzhe Zhang , Huixuan Zhang , Xiaojun Wan

Recent advances in large language models (LLMs) have shown promising results in medical diagnosis, with some studies indicating superior performance compared to human physicians in specific scenarios. However, the diagnostic capabilities of…

人工智能 · 计算机科学 2025-03-24 Zhoujian Sun , Ziyi Liu , Cheng Luo , Jiebin Chu , Zhengxing Huang

Data contamination has received increasing attention in the era of large language models (LLMs) due to their reliance on vast Internet-derived training corpora. To mitigate the risk of potential data contamination, LLM benchmarking has…

机器学习 · 计算机科学 2025-10-01 Simin Chen , Yiming Chen , Zexin Li , Yifan Jiang , Zhongwei Wan , Yixin He , Dezhi Ran , Tianle Gu , Haizhou Li , Tao Xie , Baishakhi Ray

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

计算与语言 · 计算机科学 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

The transition of Large Language Models (LLMs) from passive knowledge retrievers to autonomous clinical agents demands a shift in evaluation-from static accuracy to dynamic behavioral reliability. To explore this boundary in dentistry, a…

As large language models (LLMs) advance in conversational and reasoning capabilities, their practical application in healthcare has become a critical research focus. However, there is a notable gap between the performance of medical LLMs on…

We present a framework for training large language models (LLMs) as diagnostic agents with reinforcement learning, enabling them to manage multi-turn interactive diagnostic processes, adaptively select examinations, and commit to final…

Recent advances in deep research systems enable large language models to retrieve, synthesize, and reason over large-scale external knowledge. In medicine, developing clinical guidelines critically depends on such deep evidence integration.…

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

计算与语言 · 计算机科学 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

Users typically engage with LLMs interactively, yet most existing benchmarks evaluate them in a static, single-turn format, posing reliability concerns in interactive scenarios. We identify a key obstacle towards reliability: LLMs are…

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

计算与语言 · 计算机科学 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

Large language models (LLMs) have excelled across domains, also delivering notable performance on the medical evaluation benchmarks, such as MedQA. However, there still exists a significant gap between the reported performance and the…

计算与语言 · 计算机科学 2024-06-06 Yuxuan Zhou , Xien Liu , Chen Ning , Ji Wu

As large language models (LLMs) become increasingly integrated into clinical decision-making, ensuring transparent and trustworthy reasoning is essential. However, existing evaluation strategies of LLMs' medical reasoning capability either…

Large language models (LLMs) have saturated standard medical benchmarks that test factual recall, yet their ability to perform higher-order reasoning, such as synthesizing evidence from multiple sources, remains critically under-explored.…

计算与语言 · 计算机科学 2026-05-12 Huy Hoang Ha , Benoit Favre , Francois Portet

While Large Language Models (LLMs) excel on standardized medical exams, high scores often fail to translate to high-quality responses for real-world medical queries. Current evaluations rely heavily on multiple-choice questions, failing to…

The potential of Multimodal Large Language Models (MLLMs) in domain of medical imaging raise the demands of systematic and rigorous evaluation frameworks that are aligned with the real-world medical imaging practice. Existing practices that…

计算与语言 · 计算机科学 2026-04-16 Zhijie Bao , Fangke Chen , Licheng Bao , Chenhui Zhang , Wei Chen , Jiajie Peng , Zhongyu Wei
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