相关论文: Multiscale dynamical characterization of cortical …

The brain may be thought of as a many-body architecture with a spatio-temporal dynamics described by neuronal structures. The oscillatory nature of brain activity allows these structures (nodes) to be described as a set of coupled…

Higher brain function relies upon the ability to flexibly integrate information across specialized communities of brain regions, however it is unclear how this mechanism manifests over time. In this study, we use time-resolved network…

We propose a novel approach to investigate the brain mechanisms that support coordination of behavior between individuals. Brain states in single individuals defined by the patterns of functional connectivity between brain regions are used…

Brain functional connectivity alterations, that is, pathological changes in the signal exchange between areas of the brain, occur in several neurological diseases, including neurodegenerative and neuropsychiatric ones. They consist in…

Cortical neurons exhibit a hierarchy of timescales across brain regions in response to input stimuli, which is thought to be crucial for information processing of different temporal scales. Modeling studies suggest that both intra-regional…

The complexity of neural dynamics stems in part from the complexity of the underlying anatomy. Yet how the organization of white matter architecture constrains how the brain transitions from one cognitive state to another remains unknown.…

Experimental fMRI studies have shown that spontaneous brain activity i.e. in the absence of any external input, exhibit complex spatial and temporal patterns of co-activity between segregated brain regions. These so-called large-scale…

Neuronal networks alternate between high- and low-activity regimes, known as up and down states. They also display rhythmic patterns essential for perception, memory consolidation, and sensory processing. Despite their importance, the…

The human brain is ultimately responsible for all thoughts and movements that the body produces. This allows humans to successfully interact with their environment. If the brain is not functioning properly many abilities of human can be…

The human cortex is never at rest but in a state of sparse and noisy neural activity that can be detected at broadly diverse resolution scales. It has been conjectured that such a state is best described as a critical dynamical process --…

We report measurements of the brain activity of subjects engaged in behavioral exchanges with their environments. We observe brain states which are characterized by coordinated oscillation of populations of neurons that are changing rapidly…

The objective of this paper is to review physiological and computational aspects of the responsiveness of the cerebral cortex to stimulation, and how responsiveness depends on the state of the system. This correspondence between brain state…

Neurons, as eukaryotic cells, have powerful internal computation capabilities. One neuron can have many distinct states, and brains can use this capability. Processes of neuron growth and maintenance use chemical signalling between cell…

Adolescence is marked by rapid development of executive function. Mounting evidence suggests that executive function in adults may be driven by dynamic control of neurophysiological processes. Yet, how these dynamics evolve over adolescence…

Cortical neurons emit seemingly erratic trains of action potentials or "spikes," and neural network dynamics emerge from the coordinated spiking activity within neural circuits. These rich dynamics manifest themselves in a variety of…

Sleep is characterized by non-rapid eye movement (nREM) sleep, originating from widespread neuronal synchrony, and REM sleep, with neuronal desynchronization akin to waking behavior. While these were thought to be global brain states,…

Balanced neural networks -- in which excitatory and inhibitory inputs compensate each other on average -- give rise to a dynamical phase dominated by fluctuations called asynchronous state, crucial for brain functioning. However, structural…

The underlying physiological mechanisms of generating conscious states are still unknown. To make progress on the problem of consciousness, we will need to experimentally design a system that evolves in a similar way our brains do. Recent…

The framework of Modern Theory of Critical State Transitions considers the relation between different levels of organization in complex systems in terms of Critical State Transitions. A State Transition between levels entails changes of…

Neural synchronization is believed to be critical for many brain functions. It frequently exhibits temporal variability, but it is not known if this variability has a specific temporal patterning. This study explores these…