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Designing biological sequences that satisfy multiple, often conflicting, functional and biophysical criteria remains a central challenge in biomolecule engineering. While discrete flow matching models have recently shown promise for…

机器学习 · 计算机科学 2025-05-15 Tong Chen , Yinuo Zhang , Sophia Tang , Pranam Chatterjee

Modeling and synthesizing real sRGB noise is crucial for various low-level vision tasks, such as building datasets for training image denoising systems. The distribution of real sRGB noise is highly complex and affected by a multitude of…

计算机视觉与模式识别 · 计算机科学 2024-11-01 Young Joo Han , Ha-Jin Yu

Recent progress in large-scale flow and diffusion models raised two fundamental algorithmic challenges: (i) control-based reward adaptation of pre-trained flows, and (ii) integration of multiple models, i.e., flow merging. While current…

机器学习 · 计算机科学 2026-02-10 Riccardo De Santi , Malte Franke , Ya-Ping Hsieh , Andreas Krause

Deep learning-based surface electromyography (sEMG) gesture recognition is frequently bottlenecked by data scarcity and limited subject diversity. While synthetic data generation via Generative Adversarial Networks (GANs) and diffusion…

人机交互 · 计算机科学 2026-04-16 Boxuan Jiang , Chenyun Dai , Can Han

Magnetic Resonance Spectroscopic Imaging (MRSI) is an essential tool for quantifying metabolites in the body, but the low spatial resolution limits its clinical applications. Deep learning-based super-resolution methods provided promising…

图像与视频处理 · 电气工程与系统科学 2022-07-22 Siyuan Dong , Gilbert Hangel , Eric Z. Chen , Shanhui Sun , Wolfgang Bogner , Georg Widhalm , Chenyu You , John A. Onofrey , Robin de Graaf , James S. Duncan

We develop a \emph{flow-matching framework} for transporting probability measures under control-affine dynamics and for steering systems to points or target sets. Starting from the continuity equation associated with the control affine…

最优化与控制 · 数学 2026-05-06 Karthik Elamvazhuthi

This paper introduces a novel framework for image quality transfer based on conditional flow matching (CFM). Unlike conventional generative models that rely on iterative sampling or adversarial objectives, CFM learns a continuous flow…

计算机视觉与模式识别 · 计算机科学 2025-10-15 Huu Tien Nguyen , Ahmed Karam Eldaly

Discrete Diffusion and Flow Matching models have significantly advanced generative modeling for discrete structures, including graphs. However, the dependencies between intermediate noisy states lead to error accumulation and propagation…

机器学习 · 计算机科学 2025-06-24 Yoann Boget

Diffusion-based Deep Generative Models (DDGMs) offer state-of-the-art performance in generative modeling. Their main strength comes from their unique setup in which a model (the backward diffusion process) is trained to reverse the forward…

机器学习 · 计算机科学 2022-06-02 Kamil Deja , Anna Kuzina , Tomasz Trzciński , Jakub M. Tomczak

Image denoising is a fundamental and challenging task in the field of computer vision. Most supervised denoising methods learn to reconstruct clean images from noisy inputs, which have intrinsic spectral bias and tend to produce…

计算机视觉与模式识别 · 计算机科学 2023-09-20 Yujin Wang , Lingen Li , Tianfan Xue , Jinwei Gu

In this paper, we explore a principal way to enhance the quality of object masks produced by different segmentation models. We propose a model-agnostic solution called SegRefiner, which offers a novel perspective on this problem by…

计算机视觉与模式识别 · 计算机科学 2023-12-20 Mengyu Wang , Henghui Ding , Jun Hao Liew , Jiajun Liu , Yao Zhao , Yunchao Wei

Generative models, including diffusion and flow-based models, often exhibit systematic biases that degrade sample quality, particularly in high-dimensional settings. We revisit refinement methods and show that effective bias correction can…

机器学习 · 计算机科学 2026-01-30 Xin Peng , Ang Gao

Elucidating reaction mechanisms hinges on efficiently generating transition states (TSs), products, and complete reaction networks. Recent generative models, such as diffusion models for TS sampling and sequence-based architectures for…

化学物理 · 物理学 2025-11-06 Ping Tuo , Jiale Chen , Ju Li

Discrete diffusion models have emerged as a promising direction for vision-language tasks, offering bidirectional context modeling and theoretical parallelization. However, their practical application is severely hindered by a…

计算与语言 · 计算机科学 2025-10-24 Yatai Ji , Teng Wang , Yuying Ge , Zhiheng Liu , Sidi Yang , Ying Shan , Ping Luo

Flow-based generative modeling is a powerful tool for solving inverse problems in physical sciences that can be used for sampling and likelihood evaluation with much lower inference times than traditional methods. We propose to refine flows…

机器学习 · 计算机科学 2024-10-31 Benjamin Holzschuh , Nils Thuerey

Inverse generation problems, such as denoising without ground truth observations, is a critical challenge in many scientific inquiries and real-world applications. While recent advances in generative models like diffusion models,…

机器学习 · 计算机科学 2025-02-18 Yuchen Zhang , Jian Zhou

Flow-matching generative models are increasingly used to simulate cell responses to biological perturbations. However, the design space for building such models is large and underexplored. We systematically analyse the design space of flow…

计算机视觉与模式识别 · 计算机科学 2026-03-31 Charles Jones , Emmanuel Noutahi , Jason Hartford , Cian Eastwood

Existing dominant methods for audio generation include Generative Adversarial Networks (GANs) and diffusion-based methods like Flow Matching. GANs suffer from slow convergence during training, while diffusion methods require multi-step…

音频与语音处理 · 电气工程与系统科学 2026-03-10 Zengwei Yao , Wei Kang , Han Zhu , Liyong Guo , Lingxuan Ye , Fangjun Kuang , Weiji Zhuang , Zhaoqing Li , Zhifeng Han , Long Lin , Daniel Povey

Virtual instrument generation requires maintaining consistent timbre across different pitches and velocities, a challenge that existing note-level models struggle to address. We present FlowSynth, which combines distributional flow matching…

声音 · 计算机科学 2025-10-27 Qihui Yang , Randal Leistikow , Yongyi Zang

Diffusion-based models demonstrate impressive generation capabilities. However, they also have a massive number of parameters, resulting in enormous model sizes, thus making them unsuitable for deployment on resource-constraint devices.…

计算机视觉与模式识别 · 计算机科学 2024-09-04 Avideep Mukherjee , Soumya Banerjee , Piyush Rai , Vinay P. Namboodiri