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Purpose: Pulmonary embolism (PE) is a significant cause of mortality in the United States. The objective of this study is to implement deep learning (DL) models using Computed Tomography Pulmonary Angiography (CTPA), clinical data, and PE…

Background: Computational fluid dynamics (CFD) is increasingly used to assess blood flow conditions in patients with congenital heart disease (CHD). This requires patient-specific anatomy, usually obtained from segmented 3D cardiovascular…

Rationale: Computer aided detection (CAD) algorithms for Pulmonary Embolism (PE) algorithms have been shown to increase radiologists' sensitivity with a small increase in specificity. However, CAD for PE has not been adopted into clinical…

Machine learning models for radiology benefit from large-scale data sets with high quality labels for abnormalities. We curated and analyzed a chest computed tomography (CT) data set of 36,316 volumes from 19,993 unique patients. This is…

图像与视频处理 · 电气工程与系统科学 2020-10-14 Rachel Lea Draelos , David Dov , Maciej A. Mazurowski , Joseph Y. Lo , Ricardo Henao , Geoffrey D. Rubin , Lawrence Carin

Abdominal aortic aneurysms (AAAs) are pathologic dilatations of the abdominal aorta posing a high fatality risk upon rupture. Studying AAA progression and rupture risk often involves in-silico blood flow modelling with computational fluid…

计算机视觉与模式识别 · 计算机科学 2025-07-31 Patryk Rygiel , Julian Suk , Christoph Brune , Kak Khee Yeung , Jelmer M. Wolterink

Accurate intraoperative and postoperative diagnosis of spread through air spaces (STAS) is essential for guiding surgical decisions and postoperative management in lung cancer. However, histopathological assessment is labor-intensive and is…

Segmentation of medical images is a fundamental task with numerous applications. While MRI, CT, and PET modalities have significantly benefited from deep learning segmentation techniques, more recent modalities, like functional ultrasound…

图像与视频处理 · 电气工程与系统科学 2025-07-24 Hana Sebia , Thomas Guyet , Mickaël Pereira , Marco Valdebenito , Hugues Berry , Benjamin Vidal

To correct for respiratory motion in PET imaging, an interpretable and unsupervised deep learning technique, FlowNet-PET, was constructed. The network was trained to predict the optical flow between two PET frames from different breathing…

图像与视频处理 · 电气工程与系统科学 2022-08-04 Teaghan O'Briain , Carlos Uribe , Kwang Moo Yi , Jonas Teuwen , Ioannis Sechopoulos , Magdalena Bazalova-Carter

Purpose: To develop a machine learning model to classify the severity grades of pulmonary edema on chest radiographs. Materials and Methods: In this retrospective study, 369,071 chest radiographs and associated radiology reports from 64,581…

图像与视频处理 · 电气工程与系统科学 2021-01-08 Steven Horng , Ruizhi Liao , Xin Wang , Sandeep Dalal , Polina Golland , Seth J Berkowitz

A standard dose of radioactive tracer must be delivered into the patients body to obtain high-quality Positron Emission Tomography (PET) images for diagnostic purposes, which raises the risk of radiation harm. A reduced tracer dose, on the…

Deep learning-based automatic segmentation methods have become state-of-the-art. However, they are often not robust enough for direct clinical application, as domain shifts between training and testing data affect their performance. Failure…

图像与视频处理 · 电气工程与系统科学 2023-12-07 Helena Williams , João Pedrosa , Muhammad Asad , Laura Cattani , Tom Vercauteren , Jan Deprest , Jan D'hooge

Purpose: Automatic methods are required for the early detection of hepatic steatosis to avoid progression to cirrhosis and cancer. Here, we developed a fully automated deep learning pipeline to quantify hepatic steatosis on non-contrast…

定量方法 · 定量生物学 2022-02-08 Zhongyi Zhang , Jakob Weiss , Jana Taron , Roman Zeleznik , Michael T. Lu , Hugo J. W. L. Aerts

BACKGROUND AND PURPOSE: Deep learning has been demonstrated effective in many neuroimaging applications. However, in many scenarios, the number of imaging sequences capturing information related to small vessel disease lesions is…

As the demand for more descriptive machine learning models grows within medical imaging, bottlenecks due to data paucity will exacerbate. Thus, collecting enough large-scale data will require automated tools to harvest data/label pairs from…

图像与视频处理 · 电气工程与系统科学 2019-10-01 Bo Zhou , Adam P. Harrison , Jiawen Yao , Chi-Tung Cheng , Jing Xiao , Chien-Hung Liao , Le Lu

Purpose: To develop and evaluate a semi-supervised learning model for intracranial hemorrhage detection and segmentation on an out-of-distribution head CT evaluation set. Materials and Methods: This retrospective study used semi-supervised…

图像与视频处理 · 电气工程与系统科学 2024-04-11 Emily Lin , Esther Yuh

Accurate tooth volume segmentation is a prerequisite for computer-aided dental analysis. Deep learning-based tooth segmentation methods have achieved satisfying performances but require a large quantity of tooth data with ground truth. The…

图像与视频处理 · 电气工程与系统科学 2022-08-04 Weiwei Cui , Yaqi Wang , Yilong Li , Dan Song , Xingyong Zuo , Jiaojiao Wang , Yifan Zhang , Huiyu Zhou , Bung san Chong , Liaoyuan Zeng , Qianni Zhang

This study evaluates publicly available deep-learning based lung segmentation models in transplant-eligible patients to determine their performance across disease severity levels, pathology categories, and lung sides, and to identify…

计算机视觉与模式识别 · 计算机科学 2025-09-19 Jisoo Lee , Michael R. Harowicz , Yuwen Chen , Hanxue Gu , Isaac S. Alderete , Lin Li , Maciej A. Mazurowski , Matthew G. Hartwig

Abstract Background: Pulmonary function tests (PFTs) and computed tomography (CT) imaging are vital in diagnosing, managing, and monitoring lung diseases. A common issue in practice is the lack of access to recorded pulmonary functions…

图像与视频处理 · 电气工程与系统科学 2024-08-13 Kaiwen Geng , Zhiyi Shi , Xiaoyan Zhao , Alaa Ali , Jing Wang , Joseph Leader , Jiantao Pu

Based on CT and MRI images acquired from normal pressure hydrocephalus (NPH) patients, using machine learning methods, we aim to establish a multi-modal and high-performance automatic ventricle segmentation method to achieve efficient and…

医学物理 · 物理学 2022-02-02 Xi Zhou , Qinghao Ye , Xiaolin Yang , Jiakuan Chen , Haiqin Ma , Jun Xia , Javier Del Ser , Guang Yang

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality worldwide. Identifying those at highest risk of deterioration would allow more effective distribution of preventative and surveillance resources.…

计算机视觉与模式识别 · 计算机科学 2019-05-29 David Chettrit , Orna Bregman Amitai , Itamar Tamir , Amir Bar , Eldad Elnekave