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As the number of dementia patients rises, the need for accurate diagnostic procedures rises as well. Current methods, like using an MRI scan, rely on human input, which can be inaccurate. However, the decision logic behind machine learning…

图像与视频处理 · 电气工程与系统科学 2024-06-28 Tyler Morris , Ziming Liu , Longjian Liu , Xiaopeng Zhao

Cognitive decline is a natural part of aging. However, under some circumstances, this decline is more pronounced than expected, typically due to disorders such as Alzheimer's disease. Early detection of an anomalous decline is crucial, as…

Automatic recognition of disordered and elderly speech remains a highly challenging task to date due to the difficulty in collecting such data in large quantities. This paper explores a series of approaches to integrate domain adapted SSL…

声音 · 计算机科学 2023-06-23 Shujie Hu , Xurong Xie , Zengrui Jin , Mengzhe Geng , Yi Wang , Mingyu Cui , Jiajun Deng , Xunying Liu , Helen Meng

Speech pauses, alongside content and structure, offer a valuable and non-invasive biomarker for detecting dementia. This work investigates the use of pause-enriched transcripts in transformer-based language models to differentiate the…

音频与语音处理 · 电气工程与系统科学 2024-08-28 Franziska Braun , Sebastian P. Bayerl , Florian Hönig , Hartmut Lehfeld , Thomas Hillemacher , Tobias Bocklet , Korbinian Riedhammer

Alzheimer's disease (AD) is a common form of dementia that severely impacts patient health. As AD impairs the patient's language understanding and expression ability, the speech of AD patients can serve as an indicator of this disease. This…

音频与语音处理 · 电气工程与系统科学 2023-07-07 Hongmin Cai , Xiaoke Huang , Zhengliang Liu , Wenxiong Liao , Haixing Dai , Zihao Wu , Dajiang Zhu , Hui Ren , Quanzheng Li , Tianming Liu , Xiang Li

Alzheimer's disease (AD) is a progressive neurodegenerative disease and recently attracts extensive attention worldwide. Speech technology is considered a promising solution for the early diagnosis of AD and has been enthusiastically…

音频与语音处理 · 电气工程与系统科学 2021-10-05 Ying Qin , Wei Liu , Zhiyuan Peng , Si-Ioi Ng , Jingyu Li , Haibo Hu , Tan Lee

This paper presents a novel framework for Speech Activity Detection (SAD). Inspired by the recent success of multi-task learning approaches in the speech processing domain, we propose a novel joint learning framework for SAD. We utilise…

音频与语音处理 · 电气工程与系统科学 2020-04-06 Tharindu Fernando , Sridha Sridharan , Mitchell McLaren , Darshana Priyasad , Simon Denman , Clinton Fookes

An effective way to increase the noise robustness of automatic speech recognition is to label noisy speech features as either reliable or unreliable (missing) prior to decoding, and to replace the missing ones by clean speech estimates. We…

声音 · 计算机科学 2009-01-19 J. F. Gemmeke , B. Cranen

Dementia is a progressive cognitive syndrome with Alzheimer's disease (AD) as the leading cause. Conversation-based AD detection offers a cost-effective alternative to clinical methods, as language dysfunction is an early biomarker of AD.…

计算与语言 · 计算机科学 2025-02-27 Arezo Shakeri , Mina Farmanbar , Krisztian Balog

Artificial intelligence holds great promise for expanding access to expert medical knowledge and reasoning. However, most evaluations of language models rely on static vignettes and multiple-choice questions that fail to reflect the…

Although personalized automatic speech recognition (ASR) models have recently been designed to recognize even severely impaired speech, model performance may degrade over time for persons with degenerating speech. The aims of this study…

音频与语音处理 · 电气工程与系统科学 2022-11-02 Katrin Tomanek , Katie Seaver , Pan-Pan Jiang , Richard Cave , Lauren Harrel , Jordan R. Green

Alzheimer's Disease (AD) is a progressive neurodegenerative condition that adversely affects cognitive abilities. Language-related changes can be automatically identified through the analysis of outputs from linguistic assessment tasks,…

With the global population aging rapidly, Alzheimer's disease (AD) is particularly prominent in older adults, which has an insidious onset and leads to a gradual, irreversible deterioration in cognitive domains (memory, communication,…

音频与语音处理 · 电气工程与系统科学 2023-03-15 Jinchao Li , Kaitao Song , Junan Li , Bo Zheng , Dongsheng Li , Xixin Wu , Xunying Liu , Helen Meng

Self-supervised learning (SSL) based speech foundation models have been applied to a wide range of ASR tasks. However, their application to dysarthric and elderly speech via data-intensive parameter fine-tuning is confronted by in-domain…

音频与语音处理 · 电气工程与系统科学 2024-07-22 Shujie Hu , Xurong Xie , Mengzhe Geng , Zengrui Jin , Jiajun Deng , Guinan Li , Yi Wang , Mingyu Cui , Tianzi Wang , Helen Meng , Xunying Liu

Dementia in the elderly has recently become the most usual cause of cognitive decline. The proliferation of dementia cases in aging societies creates a remarkable economic as well as medical problems in many communities worldwide. A…

神经元与认知 · 定量生物学 2019-06-20 Tomasz M. Rutkowski , Marcin Koculak , Masato S. Abe , Mihoko Otake-Matsuura

Automatic speech recognition (ASR) technology can aid in the detection, monitoring, and assessment of depressive symptoms in individuals. ASR systems have been used as a tool to analyze speech patterns and characteristics that are…

人机交互 · 计算机科学 2023-08-17 Alice Othmani , Muhammad Muzammel

Early diagnosis of Alzheimer's Disease (AD) faces multiple data-related challenges, including high variability in patient data, limited access to specialized diagnostic tests, and overreliance on single-type indicators. These challenges are…

定量方法 · 定量生物学 2025-03-05 Yizong Xing , Dhita Putri Pratama , Yuke Wang , Yufan Zhang , Brian E. Chapman

This paper proposes a modeling framework for dynamic topic evolution based on temporal large language models. The method first uses a large language model to obtain contextual embeddings of text and then introduces a temporal decay function…

计算与语言 · 计算机科学 2025-11-04 Di Wu , Shuaidong Pan

The early signs of cognitive decline are often noticeable in conversational speech, and identifying those signs is crucial in dealing with later and more serious stages of neurodegenerative diseases. Clinical detection is costly and…

Non-autoregressive models greatly improve decoding speed over typical sequence-to-sequence models, but suffer from degraded performance. Infilling and iterative refinement models make up some of this gap by editing the outputs of a…

音频与语音处理 · 电气工程与系统科学 2020-10-28 Ethan A. Chi , Julian Salazar , Katrin Kirchhoff