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Societies worldwide are rapidly entering a super-aged era, making elderly health a pressing concern. The aging population is increasing the burden on national economies and households. Dementia cases are rising significantly with this…

人工智能 · 计算机科学 2025-06-03 Chanwoo Park , Anna Seo Gyeong Choi , Sunghye Cho , Chanwoo Kim

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease affecting 50 million people worldwide. Low-cost, accurate identification of key markers of AD is crucial for timely diagnosis and intervention. Language impairment is one…

计算与语言 · 计算机科学 2025-05-27 Tingyu Mo , Jacqueline C. K. Lam , Victor O. K. Li , Lawrence Y. L. Cheung

The main objective of this paper is to propose an approach for developing an Artificial Intelligence (AI)-powered Language Assessment (LA) tool. Such tools can be used to assess language impairments associated with dementia in older adults.…

计算与语言 · 计算机科学 2022-09-27 Mahboobeh Parsapoor , Muhammad Raisul Alam , Alex Mihailidis

Major Depressive Disorder is one of the leading causes of disability worldwide, yet its diagnosis still depends largely on subjective clinical assessments. Integrating Artificial Intelligence (AI) holds promise for developing objective,…

人工智能 · 计算机科学 2026-05-01 Dorsa Macky Aleagha , Payam Zohari , Mostafa Haghir Chehreghani

Speech, language, and communication deficits are present in most neurodegenerative syndromes. They enable the early detection, diagnosis, treatment planning, and monitoring of neurocognitive disease progression as part of traditional…

计算与语言 · 计算机科学 2023-12-07 Charalambos Themistocleous , Kyrana Tsapkini , Dimitrios Kokkinakis

In the past decade, there has been a surge in research examining the use of voice and speech analysis as a means of detecting neurodegenerative diseases such as Alzheimer's. Many studies have shown that certain acoustic features can be used…

音频与语音处理 · 电气工程与系统科学 2023-07-20 Vrindha M. K. , Geethu V. , Anurenjan P. R. , Deepak S. , Sreeni K. G.

Speech is a scalable and non-invasive biomarker for early mental health screening. However, widely used depression datasets like DAIC-WOZ exhibit strong coupling between linguistic sentiment and diagnostic labels, encouraging models to…

计算与语言 · 计算机科学 2026-01-05 Yuxin Li , Xiangyu Zhang , Yifei Li , Zhiwei Guo , Haoyang Zhang , Eng Siong Chng , Cuntai Guan

Introduction: We present a screening method for early dementia using features based on sound objects as voice biomarkers. Methods: The final dataset used for machine learning models consisted of 266 observations, with a distribution of 186…

Speech is usually used for constructing an automatic Alzheimer's dementia (AD) detection system, as the acoustic and linguistic abilities show a decline in people living with AD at the early stages. However, speech includes not only…

音频与语音处理 · 电气工程与系统科学 2024-10-11 Yilin Pan , Yanpei Shi , Yijia Zhang , Mingyu Lu

Alzheimer's disease is estimated to affect around 50 million people worldwide and is rising rapidly, with a global economic burden of nearly a trillion dollars. This calls for scalable, cost-effective, and robust methods for detection of…

音频与语音处理 · 电气工程与系统科学 2020-09-03 Utkarsh Sarawgi , Wazeer Zulfikar , Nouran Soliman , Pattie Maes

Early detection of cognitive decline is crucial for enabling interventions that can slow neurodegenerative disease progression. Traditional diagnostic approaches rely on labor-intensive clinical assessments, which are impractical for…

计算与语言 · 计算机科学 2025-09-04 Kristin Qi , Youxiang Zhu , Caroline Summerour , John A. Batsis , Xiaohui Liang

Mild Cognitive Impairment (MCI) is an early stage of Alzheimer's disease (AD), a form of neurodegenerative disorder. Early identification of MCI is crucial for delaying its progression through timely interventions. Existing research has…

音频与语音处理 · 电气工程与系统科学 2024-10-18 Kristin Qi , Jiatong Shi , Caroline Summerour , John A. Batsis , Xiaohui Liang

Automatic Speech Understanding (ASU) aims at human-like speech interpretation, providing nuanced intent, emotion, sentiment, and content understanding from speech and language (text) content conveyed in speech. Typically, training a robust…

声音 · 计算机科学 2024-04-30 Tiantian Feng , Xuan Shi , Rahul Gupta , Shrikanth S. Narayanan

Alzheimer's Disease (AD) is nowadays the most common form of dementia, and its automatic detection can help to identify symptoms at early stages, so that preventive actions can be carried out. Moreover, non-intrusive techniques based on…

计算与语言 · 计算机科学 2020-11-21 Mireia Farrús , Joan Codina-Filbà

Early identification of stroke symptoms is essential for enabling timely intervention and improving patient outcomes, particularly in prehospital settings. This study presents a fast, non-invasive multimodal deep learning framework for…

计算机视觉与模式识别 · 计算机科学 2026-03-19 Ngoc-Khai Hoang , Thi-Nhu-Mai Nguyen , Huy-Hieu Pham

This study addresses the TAUKADIAL challenge, focusing on the classification of speech from people with Mild Cognitive Impairment (MCI) and neurotypical controls. We conducted three experiments comparing five machine-learning methods:…

神经元与认知 · 定量生物学 2024-08-30 Cong Zhang , Wenxing Guo , Hongsheng Dai

Automatic detection and severity assessment of dysarthria are crucial for delivering targeted therapeutic interventions to patients. While most existing research focuses primarily on speech modality, this study introduces a novel approach…

人工智能 · 计算机科学 2025-04-29 Anuprabha M , Krishna Gurugubelli , V Kesavaraj , Anil Kumar Vuppala

Speech-based analysis offers a scalable and non-invasive approach for detecting cognitive decline, yet progress has been constrained by the limited availability of clinically validated datasets collected under realistic conditions. We…

Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

神经元与认知 · 定量生物学 2025-04-24 Zhenguang Zhong , Zhixuan Wang

We jointly model longitudinal values of a psychometric test and diagnosis of dementia. The model is based on a continuous-time latent process representing cognitive ability. The link between the latent process and the observations is…

统计理论 · 数学 2007-06-13 Julien Ganiayre , Daniel Commenges , Luc Letenneur