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In computer-aided drug discovery (CADD), virtual screening (VS) is used for identifying the drug candidates that are most likely to bind to a molecular target in a large library of compounds. Most VS methods to date have focused on using…

机器学习 · 计算机科学 2022-11-09 Andac Demir , Baris Coskunuzer , Ignacio Segovia-Dominguez , Yuzhou Chen , Yulia Gel , Bulent Kiziltan

Deep neural networks (DNNs) have become one of the enabling technologies in many safety-critical applications, e.g., autonomous driving and medical image analysis. DNN systems, however, suffer from various kinds of threats, such as…

机器学习 · 计算机科学 2020-10-19 Yu Li , Min Li , Bo Luo , Ye Tian , Qiang Xu

Background subtraction is a fundamental task in computer vision with numerous real-world applications, ranging from object tracking to video surveillance. Dynamic backgrounds poses a significant challenge here. Supervised deep…

计算机视觉与模式识别 · 计算机科学 2023-03-07 Fateme Bahri , Nilanjan Ray

Virtual Screening is an essential technique in the early phases of drug discovery, aimed at identifying promising drug candidates from vast molecular libraries. Recently, ligand-based virtual screening has garnered significant attention due…

生物大分子 · 定量生物学 2024-11-22 Gengmo Zhou , Zhen Wang , Feng Yu , Guolin Ke , Zhewei Wei , Zhifeng Gao

Real-world observational data often contain existing or emerging heterogeneous subpopulations that deviate from global patterns. The majority of models tend to overlook these underrepresented groups, leading to inaccurate or even harmful…

机器学习 · 计算机科学 2025-06-13 Tina Behrouzi , Sana Tonekaboni , Rahul G. Krishnan , Anna Goldenberg

Scene Parsing is a crucial step to enable autonomous systems to understand and interact with their surroundings. Supervised deep learning methods have made great progress in solving scene parsing problems, however, come at the cost of…

计算机视觉与模式识别 · 计算机科学 2019-03-26 Keng-Chi Liu , Yi-Ting Shen , Jan P. Klopp , Liang-Gee Chen

We introduce a deep learning architecture for structure-based virtual screening that generates fixed-sized fingerprints of proteins and small molecules by applying learnable atom convolution and softmax operations to each compound…

Despite the high biometric performance, finger-vein recognition systems are vulnerable to presentation attacks (aka., spoofing attacks). In this paper, we present a new and robust approach for detecting presentation attacks on finger-vein…

计算机视觉与模式识别 · 计算机科学 2019-12-04 Jag Mohan Singh , Sushma Venkatesh , Kiran B. Raja , Raghavendra Ramachandra , Christoph Busch

Deep neural networks are gaining increasing popularity for the classic text classification task, due to their strong expressive power and less requirement for feature engineering. Despite such attractiveness, neural text classification…

信息检索 · 计算机科学 2018-09-13 Yu Meng , Jiaming Shen , Chao Zhang , Jiawei Han

This paper addresses the challenge of out-of-distribution (OOD) generalization in graph machine learning, a field rapidly advancing yet grappling with the discrepancy between source and target data distributions. Traditional graph learning…

机器学习 · 计算机科学 2024-08-09 Xin Sun , Liang Wang , Qiang Liu , Shu Wu , Zilei Wang , Liang Wang

Scribble-based weakly-supervised semantic segmentation using sparse scribble supervision is gaining traction as it reduces annotation costs when compared to fully annotated alternatives. Existing methods primarily generate pseudo-labels by…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Xinliang Zhang , Lei Zhu , Hangzhou He , Lujia Jin , Yanye Lu

Although weakly supervised semantic segmentation using only image-level labels (WSSS-IL) is potentially useful, its low performance and implementation complexity still limit its application. The main causes are (a) non-detection and (b)…

计算机视觉与模式识别 · 计算机科学 2023-12-19 Sanghyun Jo , In-Jae Yu , Kyungsu Kim

Semi- and weakly-supervised learning have recently attracted considerable attention in the object detection literature since they can alleviate the cost of annotation needed to successfully train deep learning models. State-of-art…

计算机视觉与模式识别 · 计算机科学 2022-06-20 Akhil Meethal , Marco Pedersoli , Zhongwen Zhu , Francisco Perdigon Romero , Eric Granger

The core of cross-modal matching is to accurately measure the similarity between different modalities in a unified representation space. However, compared to textual descriptions of a certain perspective, the visual modality has more…

计算机视觉与模式识别 · 计算机科学 2023-12-22 Wenzhang Wei , Zhipeng Gui , Changguang Wu , Anqi Zhao , Dehua Peng , Huayi Wu

Deep learning has shown remarkable performance in medical image segmentation. However, despite its promise, deep learning has many challenges in practice due to its inability to effectively transition to unseen domains, caused by the…

计算机视觉与模式识别 · 计算机科学 2024-10-08 Dewei Hu , Hao Li , Han Liu , Jiacheng Wang , Xing Yao , Daiwei Lu , Ipek Oguz

Weakly supervised segmentation methods have gained significant attention due to their ability to reduce the reliance on costly pixel-level annotations during model training. However, the current weakly supervised nuclei segmentation…

图像与视频处理 · 电气工程与系统科学 2025-02-04 Ye Zhang , Yifeng Wang , Zijie Fang , Hao Bian , Linghan Cai , Ziyue Wang , Yongbing Zhang

Simplicity bias is the concerning tendency of deep networks to over-depend on simple, weakly predictive features, to the exclusion of stronger, more complex features. This is exacerbated in real-world applications by limited training data…

机器学习 · 计算机科学 2023-06-07 Rishabh Tiwari , Pradeep Shenoy

Visual autoregressive (AR) generation models have demonstrated strong potential for image generation, yet their next-token-prediction paradigm introduces considerable inference latency. Although speculative decoding (SD) has been proven…

计算机视觉与模式识别 · 计算机科学 2026-05-07 Haotian Dong , Ye Li , Rongwei Lu , Chen Tang , Shu-Tao Xia , Zhi Wang

This study investigates barely-supervised medical image segmentation where only few labeled data, i.e., single-digit cases are available. We observe the key limitation of the existing state-of-the-art semi-supervised solution cross pseudo…

计算机视觉与模式识别 · 计算机科学 2023-08-01 Huimin Wu , Xiaomeng Li , Yiqun Lin , Kwang-Ting Cheng

In this paper, we present a simple yet effective semi-supervised 3D object detector named DDS3D. Our main contributions have two-fold. On the one hand, different from previous works using Non-Maximal Suppression (NMS) or its variants for…

计算机视觉与模式识别 · 计算机科学 2023-03-13 Jingyu Li , Zhe Liu , Jinghua Hou , Dingkang Liang
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