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Docking-based virtual screening (VS process) selects ligands with potential pharmacological activities from millions of molecules using computational docking methods, which greatly could reduce the number of compounds for experimental…

定量方法 · 定量生物学 2021-10-26 Wei Ma , Qin Xie , Jianhang Zhang , Shiliang Li , Youjun Xu , Xiaobing Deng , Weilin Zhang

Many promising applications of supervised machine learning face hurdles in the acquisition of labeled data in sufficient quantity and quality, creating an expensive bottleneck. To overcome such limitations, techniques that do not depend on…

The task of weakly supervised temporal action localization targets at generating temporal boundaries for actions of interest, meanwhile the action category should also be classified. Pseudo-label-based methods, which serve as an effective…

计算机视觉与模式识别 · 计算机科学 2023-04-18 Jingqiu Zhou , Linjiang Huang , Liang Wang , Si Liu , Hongsheng Li

Deep regression is an important problem with numerous applications. These range from computer vision tasks such as age estimation from photographs, to medical tasks such as ejection fraction estimation from echocardiograms for disease…

计算机视觉与模式识别 · 计算机科学 2023-02-16 Weihang Dai , Xiaomeng Li , Kwang-Ting Cheng

Dynamic convolution achieves better performance for efficient CNNs at the cost of negligible FLOPs increase. However, the performance increase can not match the significantly expanded number of parameters, which is the main bottleneck in…

计算机视觉与模式识别 · 计算机科学 2023-05-29 Shwai He , Chenbo Jiang , Daize Dong , Liang Ding

Recently, deep learning(DL) methods have been proposed for the low-dose computed tomography(LdCT) enhancement, and obtain good trade-off between computational efficiency and image quality. Most of them need large number of pre-collected…

计算机视觉与模式识别 · 计算机科学 2018-08-09 Mingrui Geng , Yun Deng , Qian Zhao , Qi Xie , Dong Zeng , Dong Zeng , Wangmeng Zuo , Deyu Meng

Detecting fraudulent activities in financial and e-commerce transaction networks is crucial. One effective method for this is Densest Subgraph Discovery (DSD). However, deploying DSD methods in production systems faces substantial…

数据库 · 计算机科学 2025-04-15 Jiaxin Jiang , Siyuan Yao , Yuchen Li , Qiange Wang , Bingsheng He , Min Chen

Fast screening of drug molecules based on the ligand binding affinity is an important step in the drug discovery pipeline. Graph neural fingerprint is a promising method for developing molecular docking surrogates with high throughput and…

A lack of understanding of human biology creates a hurdle for the development of precision medicines. To overcome this hurdle we need to better understand the potential synergy between a given investigational treatment (vs. placebo or…

应用统计 · 统计学 2017-08-17 Jia Jia , Qi Tang , Wangang Xie , Richard Rode

Automated nodule segmentation is essential for computer-assisted diagnosis in ultrasound images. Nevertheless, most existing methods depend on precise pixel-level annotations by medical professionals, a process that is both costly and…

计算机视觉与模式识别 · 计算机科学 2024-07-19 Xingyue Zhao , Peiqi Li , Xiangde Luo , Meng Yang , Shi Chang , Zhongyu Li

High-throughput phenotypic screens generate vast microscopy image datasets that push the limits of generative models due to their large dimensionality. Despite the growing popularity of general-purpose models trained on natural images for…

定量方法 · 定量生物学 2025-10-24 Télio Cropsal , Rocío Mercado

Weakly supervised point cloud semantic segmentation methods that require 1\% or fewer labels, hoping to realize almost the same performance as fully supervised approaches, which recently, have attracted extensive research attention. A…

计算机视觉与模式识别 · 计算机科学 2022-09-19 Tianfang Sun , Zhizhong Zhang , Xin Tan , Yanyun Qu , Yuan Xie , Lizhuang Ma

Visual detection of Micro Air Vehicles (MAVs) has attracted increasing attention in recent years due to its important application in various tasks. The existing methods for MAV detection assume that the training set and testing set have the…

机器人学 · 计算机科学 2024-03-26 Yin Zhang , Jinhong Deng , Peidong Liu , Wen Li , Shiyu Zhao

Unsupervised visible-infrared person re-identification (UVI-ReID) has recently gained great attention due to its potential for enhancing human detection in diverse environments without labeling. Previous methods utilize intra-modality…

计算机视觉与模式识别 · 计算机科学 2024-04-11 Yexin Liu , Weiming Zhang , Athanasios V. Vasilakos , Lin Wang

Recently, One-stage Weakly Supervised Semantic Segmentation (WSSS) with image-level labels has gained increasing interest due to simplification over its cumbersome multi-stage counterpart. Limited by the inherent ambiguity of Class…

计算机视觉与模式识别 · 计算机科学 2024-03-19 Yuanchen Wu , Xichen Ye , Kequan Yang , Jide Li , Xiaoqiang Li

Existing deepfake detection methods heavily rely on static labeled datasets. However, with the proliferation of generative models, real-world scenarios are flooded with massive amounts of unlabeled fake face data from unknown sources. This…

计算机视觉与模式识别 · 计算机科学 2025-11-26 Zhiqiang Yang , Renshuai Tao , Chunjie Zhang , guodong yang , Xiaolong Zheng , Yao Zhao

Medical vision foundation models remain limited in downstream tasks, particularly volumetric medical image segmentation. While fine-tuning on labeled target-domain data improves performance, existing approaches typically rely on randomly…

图像与视频处理 · 电气工程与系统科学 2026-05-07 Jin Yang , Daniel S. Marcus , Aristeidis Sotiras

Low signal-to-noise ratio videos -- such as those from underwater sonar, ultrasound, and microscopy -- pose significant challenges for computer vision models, particularly when paired clean imagery is unavailable. We present Spatiotemporal…

计算机视觉与模式识别 · 计算机科学 2025-10-14 Suzanne Stathatos , Michael Hobley , Pietro Perona , Markus Marks

This paper is concerned with self-supervised learning for small models. The problem is motivated by our empirical studies that while the widely used contrastive self-supervised learning method has shown great progress on large model…

计算机视觉与模式识别 · 计算机科学 2021-04-19 Zhiyuan Fang , Jianfeng Wang , Lijuan Wang , Lei Zhang , Yezhou Yang , Zicheng Liu

Weakly supervised semantic segmentation (WSSS) aims to produce pixel-wise class predictions with only image-level labels for training. To this end, previous methods adopt the common pipeline: they generate pseudo masks from class activation…

计算机视觉与模式识别 · 计算机科学 2022-08-09 Sungpil Kho , Pilhyeon Lee , Wonyoung Lee , Minsong Ki , Hyeran Byun