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Following their success across many domains, transformers have also proven effective for symbolic regression (SR); however, the internal mechanisms underlying their generation of mathematical operators remain largely unexplored. Although…

机器学习 · 计算机科学 2026-02-04 Arco van Breda , Erman Acar

Advances in large-scale recording technologies now enable simultaneous measurements from multiple brain areas, offering new opportunities to study signal transmission across interacting components of neural circuits. However, neural…

神经元与认知 · 定量生物学 2025-10-27 Qi Xin , Robert E. Kass

In this paper, we propose an easily trained yet powerful representation learning approach with performance highly competitive to deep neural networks in a digital pathology image segmentation task. The method, called sparse coding driven…

计算机视觉与模式识别 · 计算机科学 2020-08-14 Jie Song , Liang Xiao , Mohsen Molaei , Zhichao Lian

Intelligent spectrum management is crucial for improving spectrum efficiency and achieving secure utilization of spectrum resources. However, existing intelligent spectrum management methods, typically based on small-scale models, suffer…

信号处理 · 电气工程与系统科学 2025-12-16 Fuhui Zhou , Chunyu Liu , Hao Zhang , Wei Wu , Qihui Wu , Tony Q. S. Quek , Chan-Byoung Chae

Large language models excel at interpreting complex natural language instructions, enabling them to perform a wide range of tasks. In the life sciences, single-cell RNA sequencing (scRNA-seq) data serves as the "language of cellular…

计算与语言 · 计算机科学 2025-01-16 Yin Fang , Xinle Deng , Kangwei Liu , Ningyu Zhang , Jingyang Qian , Penghui Yang , Xiaohui Fan , Huajun Chen

Although convolutional neural networks (CNNs) have achieved remarkable progress in weakly supervised semantic segmentation (WSSS), the effective receptive field of CNN is insufficient to capture global context information, leading to…

计算机视觉与模式识别 · 计算机科学 2022-03-17 Chunmeng Liu , Enze Xie , Wenjia Wang , Wenhai Wang , Guangyao Li , Ping Luo

We present a framework for modeling superconducting circuits that integrates classical microwave analysis with circuit quantization. Our framework enables the calculation of the lossy eigenmodes of superconducting circuits, and we…

量子物理 · 物理学 2019-03-22 Michael G. Scheer , Maxwell B. Block

The general-purpose nature of Large Language Models (LLMs) presents a significant challenge for domain-specific applications, often leading to out-of-domain (OOD) interactions that undermine the provider's intent. Existing methods for…

人工智能 · 计算机科学 2026-05-13 Elias Shaheen , Avi Mendelson

For large language models (LLMs), sparse autoencoders (SAEs) have been shown to decompose intermediate representations that often are not interpretable directly into sparse sums of interpretable features, facilitating better control and…

Computational modeling of single-cell gene expression is crucial for understanding cellular processes, but generating realistic expression profiles remains a major challenge. This difficulty arises from the count nature of gene expression…

Modern Foundation Models (FMs) are typically trained on corpora spanning a wide range of different data modalities, topics and downstream tasks. Utilizing these models can be very computationally expensive and is out of reach for most…

机器学习 · 计算机科学 2025-06-09 Andrey Zhmoginov , Jihwan Lee , Mark Sandler

Understanding the biological mechanisms of disease is crucial for medicine, and in particular, for drug discovery. AI-powered analysis of genome-scale biological data holds great potential in this regard. The increasing availability of…

Identity, response to external stimuli, and spatial architecture of a living system are central topics of molecular biology. Presently, they are largely seen as a result of the interplay between a gene repertoire and the regulatory…

分子网络 · 定量生物学 2007-05-23 M. Cosentino Lagomarsino , P. Jona , B. Bassetti

Interpreting the internal activations of neural networks can produce more faithful explanations of their behavior, but is difficult due to the complex structure of activation space. Existing approaches to scalable interpretability use…

人工智能 · 计算机科学 2025-12-18 Vincent Huang , Dami Choi , Daniel D. Johnson , Sarah Schwettmann , Jacob Steinhardt

Large-scale pre-trained vision foundation models, such as CLIP, have become de facto backbones for various vision tasks. However, due to their black-box nature, understanding the underlying rules behind these models' predictions and…

计算机视觉与模式识别 · 计算机科学 2023-10-17 Haozhe Chen , Junfeng Yang , Carl Vondrick , Chengzhi Mao

Understanding how 5' untranslated regions (5'UTRs) regulate mRNA translation is critical for controlling protein expression and designing effective therapeutic mRNAs. While recent deep learning models have shown promise in predicting…

定量方法 · 定量生物学 2026-02-27 Yuxi Lin , Yaxue Fang , Zehong Zhang , Zhouwu Liu , Siyun Zhong , Zhongfang Wang , Fulong Yu

In this work, we introduce CellxPert, a scalable multimodal foundation model that unifies single-cell and spatial multi-omics within a common representation space. CellxPert jointly encodes transcriptomic (scRNA-seq),…

基因组学 · 定量生物学 2026-05-05 Andac Demir , Erik W. Anderson , Jeremy L. Jenkins , Srayanta Mukherjee

In recent times, Large Language Models (LLMs) have captured a global spotlight and revolutionized the field of Natural Language Processing. One of the factors attributed to the effectiveness of LLMs is the model architecture used for…

机器学习 · 计算机科学 2023-08-31 Oluwaseyi Ogunfowora , Homayoun Najjaran

The success of a specific neural network architecture is closely tied to the dataset and task it tackles; there is no one-size-fits-all solution. Thus, considerable efforts have been made to quickly and accurately estimate the performances…

机器学习 · 计算机科学 2024-03-22 Dongyeong Hwang , Hyunju Kim , Sunwoo Kim , Kijung Shin

Transformer-based neural decoders have emerged as a promising approach to error correction coding, combining data-driven adaptability with efficient modeling of long-range dependencies. This paper presents a novel decoder architecture that…

信息论 · 计算机科学 2025-09-22 Chin Wa Lau , Xiang Shi , Ziyan Zheng , Haiwen Cao , Nian Guo
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