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The segmentation of optic disc(OD) and optic cup(OC) from fundus images is an important fundamental task for glaucoma diagnosis. In the clinical practice, it is often necessary to collect opinions from multiple experts to obtain the final…

图像与视频处理 · 电气工程与系统科学 2022-06-15 Junde Wu , Huihui Fang , Fangxin Shang , Zhaowei Wang , Dalu Yang , Wenshuo Zhou , Yehui Yang , Yanwu Xu

Choroid is the vascular layer of the eye, which is directly related to the incidence and severity of many ocular diseases. Optical Coherence Tomography (OCT) is capable of imaging both the cross-sectional view of retina and choroid, but the…

计算机视觉与模式识别 · 计算机科学 2019-12-12 Huihong Zhang , Jianlong Yang , Kang Zhou , Zhenjie Chai , Jun Cheng , Shenghua Gao , Jiang Liu

Retinal imaging has emerged as a powerful, non-invasive modality for detecting and quantifying biomarkers of systemic diseases-ranging from diabetes and hypertension to Alzheimer's disease and cardiovascular disorders but current insights…

图像与视频处理 · 电气工程与系统科学 2025-05-28 Tariq M Khan , Toufique Ahmed Soomro , Imran Razzak

The task of automatically segmenting 3-D surfaces representing boundaries of objects is important for quantitative analysis of volumetric images, and plays a vital role in biomedical image analysis. Recently, graph-based methods with a…

计算机视觉与模式识别 · 计算机科学 2018-01-10 Abhay Shah , Michael Abramoff , Xiaodong Wu

Optical Coherence Tomography allows ophthalmologist to obtain cross-section imaging of eye retina. Assisted with digital image analysis methods, effective disease detection could be performed. Various methods exist to extract feature from…

计算机视觉与模式识别 · 计算机科学 2018-09-11 Kuntoro Adi Nugroho

This study introduces a groundbreaking optical coherence tomography (OCT) imaging system dedicated for high-throughput screening applications using ex vivo tissue culture. Leveraging OCT's non-invasive, high-resolution capabilities, the…

Quantification of intra-retinal boundaries in optical coherence tomography (OCT) is a crucial task for studying and diagnosing neurological and ocular diseases. Since manual segmentation of layers is usually a time consuming task and relay…

计算机视觉与模式识别 · 计算机科学 2015-02-17 Mahdi Salarian

Glaucoma is a chronic eye disease that leads to irreversible vision loss. The cup to disc ratio (CDR) plays an important role in the screening and diagnosis of glaucoma. Thus, the accurate and automatic segmentation of optic disc (OD) and…

计算机视觉与模式识别 · 计算机科学 2018-02-13 Huazhu Fu , Jun Cheng , Yanwu Xu , Damon Wing Kee Wong , Jiang Liu , Xiaochun Cao

Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in…

The quality of diabetic retinopathy (DR) screening relies on the ability to correctly grade severity; however, many deep-learning (DL) classifiers cannot be easily interpreted in the clinical context. This study presents a methodology that…

计算机视觉与模式识别 · 计算机科学 2026-04-28 Pir Bakhsh Khokhar , Carmine Gravino , Fabio Palomba , Sule Yildirim Yayilgan , Sarang Shaikh

Optical Coherence Tomography (OCT) layer segmentation faces challenges due to annotation scarcity and heterogeneous label granularities across datasets. While semi-supervised learning helps alleviate label scarcity, existing methods…

计算机视觉与模式识别 · 计算机科学 2026-04-08 Yizhou Fang , Jian Zhong , Li Lin , Xiaoying Tang

Despite significant advances in artificial intelligence (AI) for computer vision, its application in medical imaging has been limited by the burden and limits of expert-generated labels. We used images from optical coherence tomography…

计算机视觉与模式识别 · 计算机科学 2018-02-27 Cecilia S. Lee , Ariel J. Tyring , Yue Wu , Sa Xiao , Ariel S. Rokem , Nicolaas P. Deruyter , Qinqin Zhang , Adnan Tufail , Ruikang K. Wang , Aaron Y. Lee

Objective: Glaucoma is the second leading cause of blindness worldwide. Glaucomatous progression can be easily monitored by analyzing the degeneration of retinal ganglion cells (RGCs). Many researchers have screened glaucoma by measuring…

图像与视频处理 · 电气工程与系统科学 2020-11-22 Hina Raja , Taimur Hassan , Muhammad Usman Akram , Naoufel Werghi

We present a cascade deep neural network to segment retinal vessels in volumetric optical coherence tomography (OCT). Two types of knowledge are infused into the network for confining the searching regions. (1) Histology. The retinal…

图像与视频处理 · 电气工程与系统科学 2019-10-22 Liyang Fang , Jianlong Yang , Lei Mou , Huihong Zhang , Zhenjie Chai , Zhi Chen , Jiang Liu

Diseases are currently managed by grading systems, where patients are stratified by grading systems into stages that indicate patient risk and guide clinical management. However, these broad categories typically lack prognostic value, and…

Age-related macular degeneration (AMD) and choroidal neovascularization (CNV)-related conditions are leading causes of vision loss worldwide, with optical coherence tomography (OCT) serving as a cornerstone for early detection and…

计算机视觉与模式识别 · 计算机科学 2026-02-26 Erfan Nourbakhsh , Nasrin Sanjari , Ali Nourbakhsh

A major cause of irreversible visual impairment is angle-closure glaucoma, which can be screened through imagery from Anterior Segment Optical Coherence Tomography (AS-OCT). Previous computational diagnostic techniques address this…

计算机视觉与模式识别 · 计算机科学 2018-09-11 Huazhu Fu , Yanwu Xu , Stephen Lin , Damon Wing Kee Wong , Baskaran Mani , Meenakshi Mahesh , Tin Aung , Jiang Liu

The performance of diagnostic Computer-Aided Design (CAD) systems for retinal diseases depends on the quality of the retinal images being screened. Thus, many studies have been developed to evaluate and assess the quality of such retinal…

图像与视频处理 · 电气工程与系统科学 2024-09-17 Saif Khalid , Hatem A. Rashwan , Saddam Abdulwahab , Mohamed Abdel-Nasser , Facundo Manuel Quiroga , Domenec Puig

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

图像与视频处理 · 电气工程与系统科学 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

Recent studies suggest that early stages of diabetic retinopathy (DR) can be diagnosed by monitoring vascular changes in the deep vascular complex. In this work, we investigate a novel method for automated DR grading based on optical…

图像与视频处理 · 电气工程与系统科学 2022-12-22 Linus Kreitner , Ivan Ezhov , Daniel Rueckert , Johannes C. Paetzold , Martin J. Menten