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Early and accurate identification of parkinsonian syndromes (PS) involving presynaptic degeneration from non-degenerative variants such as Scans Without Evidence of Dopaminergic Deficit (SWEDD) and tremor disorders, is important for…

应用统计 · 统计学 2017-03-07 R. Prashanth , Sumantra Dutta Roy , Pravat K. Mandal , Shantanu Ghosh

Epilepsy is a neurological disorder classified as the second most serious neurological disease known to humanity, after stroke. Localization of the epileptogenic zone is an important step for epileptic patient treatment, which starts with…

Early and accurate detection of Parkinson's disease (PD) is a crucial diagnostic challenge carrying immense clinical significance, for effective treatment regimens and patient management. For instance, a group of subjects termed SWEDD who…

图像与视频处理 · 电气工程与系统科学 2025-06-24 R. Prashanth

In this study we focus on the diagnosis of Parkinson's Disease (PD) based on electroencephalogram (EEG) signals. We propose a new approach inspired by the functioning of the brain that uses the dynamics, frequency and temporal content of…

系统与控制 · 电气工程与系统科学 2023-03-31 Houssem Meghnoudj , Bogdan Robu , Mazen Alamir

Parkinson's disease is a common neurological disease, entailing a multitude of motor deficiency symptoms. In this project, we developed a device with an uploaded edge machine learning algorithm that can detect the onset of freezing of gait…

信号处理 · 电气工程与系统科学 2022-11-15 Purnoor Ghuman , Tyama Lyall , Usama Mahboob , Alia Aamir , Xilin Liu

Parkinsons disease (PD) diagnosis is challenging due to subtle early clinical signs. F-DOPA PET is commonly used for early PD diagnosis. We explore the potential of machine-learning (ML) based EEG features extracted from single-channel EEG…

神经元与认知 · 定量生物学 2023-08-08 Lior Molcho , Neta B. Maimon , Neomi Hezi , Talya Zeimer , Nathan Intrator , Tanya Gurevich

Parkinson's disease (PD) is a common neurodegenerative disease with a high degree of heterogeneity in its clinical features, rate of progression, and change of variables over time. In this work, we present a novel data-driven, network-based…

应用统计 · 统计学 2020-07-01 Sanjukta Krishnagopal , Rainer Von Coelln , Lisa M. Shulman , Michelle Girvan

One of the symptoms observed in the early stages of Parkinson's Disease (PD) is speech impairment. Speech disorders can be used to detect this disease before it degenerates. This work analyzes speech features and machine learning approaches…

音频与语音处理 · 电气工程与系统科学 2021-11-22 Adedolapo Aishat Toye , Suryaprakash Kompalli

PPINtonus is a system for the early detection of Parkinson's Disease (PD) utilizing deep-learning tonal analysis, providing a cost-effective and accessible alternative to traditional neurological examinations. Partnering with the…

音频与语音处理 · 电气工程与系统科学 2024-06-06 Varun Reddy

Parkinson's Disease PD is a progressive neurodegenerative disorder that affects motor and cognitive functions with early diagnosis being critical for effective clinical intervention Electroencephalography EEG offers a noninvasive and…

Background: Parkinson's disease (PD) is a prevalent long-term neurodegenerative disease. Though the diagnostic criteria of PD are relatively well defined, the current medical imaging diagnostic procedures are expertise-demanding, and thus…

定量方法 · 定量生物学 2019-02-27 Jiahang Xu , Fangyang Jiao , Yechong Huang , Xinzhe Luo , Qian Xu , Ling Li , Xueling Liu , Chuantao Zuo , Ping Wu , Xiahai Zhuang

At present, the vast majority of human subjects with neurological disease are still diagnosed through in-person assessments and qualitative analysis of patient data. In this paper, we propose to use Topological Data Analysis (TDA) together…

机器学习 · 计算机科学 2020-05-07 Afra Nawar , Farhan Rahman , Narayanan Krishnamurthi , Anirudh Som , Pavan Turaga

Background and Objective: Parkinson's disease (PD) is the second most common progressive neurological condition after Alzheimer's, characterized by motor and non-motor symptoms. Developing a method to diagnose the condition in its beginning…

机器学习 · 计算机科学 2022-10-05 Paria Ghaheri , Hamid Nasiri , Ahmadreza Shateri , Arman Homafar

We present a probabilistic programmed deep kernel learning approach to personalized, predictive modeling of neurodegenerative diseases. Our analysis considers a spectrum of neural and symbolic machine learning approaches, which we assess…

机器学习 · 计算机科学 2021-01-13 Alexander Lavin

Parkinson's Disease (PD) is a degenerative neurological disorder that impairs motor and non-motor functions, significantly reducing quality of life and increasing mortality risk. Early and accurate detection of PD progression is vital for…

机器学习 · 计算机科学 2024-12-31 Abhinav Roy , Bhavesh Gyanchandani , Aditya Oza , Abhishek Sharma

Genome-Wide Association Studies (GWAS) help identify genetic variations in people with diseases such as Parkinson's disease (PD), which are less common in those without the disease. Thus, GWAS data can be used to identify genetic variations…

基因组学 · 定量生物学 2023-04-07 Ali Amelia , Lourdes Pena-Castillo , Hamid Usefi

Diagnosing Parkinson's disease is a complex task that requires the evaluation of several motor and non-motor symptoms. During diagnosis, gait abnormalities are among the important symptoms that physicians should consider. However, gait…

机器学习 · 计算机科学 2020-05-19 Imanne El Maachi , Guillaume-Alexandre Bilodeau , Wassim Bouachir

Understanding how individuals with Parkinson's disease (PD) describe cognitive experiences in their daily lives can offer valuable insights into disease-related cognitive and emotional changes. However, extracting such information from…

计算与语言 · 计算机科学 2025-11-13 Varada Khanna , Nilay Bhatt , Ikgyu Shin , Sule Tinaz , Yang Ren , Hua Xu , Vipina K. Keloth

Parkinson's disease (PD) is commonly characterized by several motor symptoms, such as bradykinesia, akinesia, rigidity, and tremor. The analysis of patients' fine motor control, particularly handwriting, is a powerful tool to support PD…

计算机视觉与模式识别 · 计算机科学 2021-01-26 Moises Diaz , Momina Moetesum , Imran Siddiqi , Gennaro Vessio

The rapid emergence of highly adaptable and reusable artificial intelligence (AI) models is set to revolutionize the medical field, particularly in the diagnosis and management of Parkinson's disease (PD). Currently, there are no effective…

机器学习 · 计算机科学 2025-02-18 Aite Zhao , Yongcan Liu , Xinglin Yu , Xinyue Xing