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Trial-based economic evaluations are typically performed on cross-sectional variables, derived from the responses for only the completers in the study, using methods that ignore the complexities of utility and cost data (e.g. skewness and…

统计方法学 · 统计学 2018-05-21 Andrea Gabrio , Michael J. Daniels , Gianluca Baio

Clustering is a crucial task in various domains of knowledge, including medicine, epidemiology, genomics, environmental science, economics, and visual sciences, among others. Methodologies for inferring the number of clusters have often…

统计方法学 · 统计学 2025-05-26 Clara Grazian

Death among subjects is common in observational studies evaluating the causal effects of interventions among geriatric or severely ill patients. High mortality rates complicate the comparison of the prevalence of adverse events (AEs)…

统计方法学 · 统计学 2024-10-08 Anthony Sisti , Andrew Zullo , Roee Gutman

The regression discontinuity (RD) design is a popular approach to causal inference in non-randomized studies. This is because it can be used to identify and estimate causal effects under mild conditions. Specifically, for each subject, the…

统计方法学 · 统计学 2014-02-11 George Karabatsos , Stephen G. Walker

An important issue in joint modelling for outcomes and longitudinal risk factors in cohort studies is to have an accurate assessment of events. Events determined based on ICD-9 codes can be very inaccurate, in particular for cardiovascular…

统计方法学 · 统计学 2025-06-25 Mirajul Islam , Michael J. Daniels , Donald Lloyd-Jones , Juned Siddique

The SAVVY project aims to improve the analyses of adverse events (AEs) in clinical trials through the use of survival techniques appropriately dealing with varying follow-up times and competing events (CEs). This paper summarizes key…

应用统计 · 统计学 2024-02-28 Kaspar Rufibach , Jan Beyersmann , Tim Friede , Claudia Schmoor , Regina Stegherr

This work is concerned with nonparametric goodness-of-fit testing in the context of nonlinear inverse problems with random observations. Bayesian posterior distributions based upon a Gaussian process prior distribution are proven to…

统计理论 · 数学 2026-02-11 Remo Kretschmann , Han Cheng Lie

Analyses of adverse events (AEs) are an important aspect of the evaluation of experimental therapies. The SAVVY (Survival analysis for AdVerse events with Varying follow-up times) project aims to improve the analyses of AE data in clinical…

We introduce a new method for estimating the mean of an outcome variable within groups when researchers only observe the average of the outcome and group indicators across a set of aggregation units, such as geographical areas. Existing…

统计方法学 · 统计学 2026-05-01 Cory McCartan , Shiro Kuriwaki

Bayesian field theory denotes a nonparametric Bayesian approach for learning functions from observational data. Based on the principles of Bayesian statistics, a particular Bayesian field theory is defined by combining two models: a…

数据分析、统计与概率 · 物理学 2007-05-23 J. C. Lemm

We study a nonparametric Bayesian approach to linear inverse problems under discrete observations. We use the discrete Fourier transform to convert our model into a truncated Gaussian sequence model, that is closely related to the classical…

统计理论 · 数学 2018-10-31 Shota Gugushvili , Aad van der Vaart , Dong Yan

In recurrent event studies, panel binary data arise when subjects are observed at discrete time points and only the recurrent event status within each observation window is recorded. Such data frequently occur in longitudinal studies due to…

统计方法学 · 统计学 2025-03-18 Pavithra Hariharan , P. G. Sankaran

The Tweedie Compound Poisson-Gamma model is routinely used for modeling non-negative continuous data with a discrete probability mass at zero. Mixed models with random effects account for the covariance structure related to the grouping…

机器学习 · 统计学 2019-02-05 Yaodong Yang , Rui Luo , Yuanyuan Liu

Nested error regression models are useful tools for analysis of grouped data, especially in the case of small area estimation. This paper suggests a nested error regression model using uncertain random effects in which the random effect in…

统计方法学 · 统计学 2017-02-28 Shonosuke Sugasawa , Tatsuya Kubokawa

In observational studies, contingency tables provide a simple and intuitive approach to study associations between categorical variables. However, any test of association in contingency tables may be biased due to unmeasured confounders.…

统计方法学 · 统计学 2025-10-10 Elaine K. Chiu , Hyunseung Kang

This paper proposes the asymmetric linear double autoregression, which jointly models the conditional mean and conditional heteroscedasticity characterized by asymmetric effects. A sufficient condition is established for the existence of a…

统计方法学 · 统计学 2021-04-22 Songhua Tan , Qianqian Zhu

Unmeasured confounding bias threatens the validity of observational studies. While sensitivity analyses and study designs have been proposed to address this issue, they often overlook the growing availability of auxiliary data. Using…

统计方法学 · 统计学 2024-10-22 Jie Kate Hu , Dafne Zorzetto , Francesca Dominici

A Bayesian multivariate model with a structured covariance matrix for multi-way nested data is proposed. This flexible modeling framework allows for positive and for negative associations among clustered observations, and generalizes the…

统计方法学 · 统计学 2024-08-27 Stef Baas , Richard J. Boucherie , Jean-Paul Fox

Comparing competing mathematical models of complex natural processes is a shared goal among many branches of science. The Bayesian probabilistic framework offers a principled way to perform model comparison and extract useful metrics for…

Functional concurrent, or varying-coefficient, regression models are commonly used in biomedical and clinical settings to investigate how the relation between an outcome and observed covariate varies as a function of another covariate. In…

统计方法学 · 统计学 2024-10-10 Mingrui Liang , Matthew D. Koslovsky , Emily T. Hebert , Darla E. Kendzor , Marina Vannucci