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Linear regression is arguably the most widely used statistical method. With fixed regressors and correlated errors, the conventional wisdom is to modify the variance-covariance estimator to accommodate the known correlation structure of the…

统计理论 · 数学 2024-10-11 Zifeng Zhang , Peng Ding , Wen Zhou , Haonan Wang

Regression to the Mean and Regression Dilution are often viewed as unrelated issues in the clinical and ecological literatures. In reality, they are different names for the same problem: measurement error in an independent variable that…

定量方法 · 定量生物学 2026-05-13 José F. Fontanari , Mauro Santos

To make informed policy recommendations from observational data, we must be able to discern true treatment effects from random noise and effects due to confounding. Difference-in-Difference techniques which match treated units to control…

统计方法学 · 统计学 2019-09-12 Nicholas Illenberger , Dylan S. Small , Pamela A. Shaw

Real-World Data (RWD), with its large sample sizes and rich clinical detail, offers a compelling alternative to randomized controlled trials (RCTs) for studying treatment effects in diverse and complex patient populations. However, its…

应用统计 · 统计学 2026-05-26 Yifei Xu , Hwiyoung Lee , Zhenyao Ye , Yezhi Pan , Jingsong Zhou , Yun Yang , Chixiang Chen , Shuo Chen

Measurement error is a pervasive issue which renders the results of an analysis unreliable. The measurement error literature contains numerous correction techniques, which can be broadly divided into those which aim to produce exactly…

统计方法学 · 统计学 2021-11-08 Dylan Spicker , Michael P Wallace , Grace Y Yi

The generalization error (risk) of a supervised statistical learning algorithm quantifies its prediction ability on previously unseen data. Inspired by exponential tilting, \citet{li2020tilted} proposed the {\it tilted empirical risk} (TER)…

机器学习 · 统计学 2025-06-10 Gholamali Aminian , Amir R. Asadi , Tian Li , Ahmad Beirami , Gesine Reinert , Samuel N. Cohen

When the regressors of a econometric linear model are nonorthogonal, it is well known that their estimation by ordinary least squares can present various problems that discourage the use of this model. The ridge regression is the most…

统计方法学 · 统计学 2024-07-04 Román Salmerón Gómez , Catalina García García , Guillermo Hortal Reina

Researchers often use linear regression to analyse randomized experiments to improve treatment effect estimation by adjusting for imbalances of covariates in the treatment and control groups. Our work offers a randomization-based inference…

统计理论 · 数学 2022-07-08 Hanzhong Liu , Yuehan Yang

Regression adjustment is broadly applied in randomized trials under the premise that it usually improves the precision of a treatment effect estimator. However, previous work has shown that this is not always true. To further understand…

统计方法学 · 统计学 2022-10-11 Katarzyna Reluga , Ting Ye , Qingyuan Zhao

Empirical risk minimization (ERM) is typically designed to perform well on the average loss, which can result in estimators that are sensitive to outliers, generalize poorly, or treat subgroups unfairly. While many methods aim to address…

机器学习 · 计算机科学 2021-03-18 Tian Li , Ahmad Beirami , Maziar Sanjabi , Virginia Smith

A regression method for proportional, or fractional, data with mixed effects is outlined, designed for analysis of datasets in which the outcomes have substantial weight at the bounds. In such cases a normal approximation is particularly…

统计方法学 · 统计学 2018-05-23 Colman Humphrey , Dan Swingley

This paper investigates the use of regularization priors in the context of treatment effect estimation using observational data where the number of control variables is large relative to the number of observations. First, the phenomenon of…

统计方法学 · 统计学 2016-12-30 P. Richard Hahn , Carlos M. Carvalho , Jingyu He , David Puelz

We argue that randomized controlled trials (RCTs) are special even among settings where average treatment effects are identified by a nonparametric unconfoundedness assumption. This claim follows from two results of Robins and Ritov (1997):…

统计方法学 · 统计学 2021-09-28 P. M. Aronow , James M. Robins , Theo Saarinen , Fredrik Sävje , Jasjeet Sekhon

Linear regression is arguably the most fundamental statistical model; however, the validity of its use in randomized clinical trials, despite being common practice, has never been crystal clear, particularly when stratified or…

统计方法学 · 统计学 2023-02-14 Wei Ma , Fuyi Tu , Hanzhong Liu

P values or risk ratios from multiple, independent studies, observational or randomized, can be computationally combined to provide an overall assessment of a research question in meta-analysis. There is a need to examine the reliability of…

统计方法学 · 统计学 2021-10-28 S. Stanley Young , Warren B. Kindzierski

Random-effects models are central to meta-analysis, yet the between-study variance is often underestimated when the number of studies is small. In such settings, confidence intervals become unduly narrow and fail to attain the nominal…

统计方法学 · 统计学 2025-11-18 Keisuke Hanada , Tomoyuki Sugimoto

Ridge regression (RR) is a regularization technique that penalizes the L2-norm of the coefficients in linear regression. One of the challenges of using RR is the need to set a hyperparameter ($\alpha$) that controls the amount of…

统计方法学 · 统计学 2020-05-08 Ariel Rokem , Kendrick Kay

Regression adjustments are often made to experimental data. Since randomization does not justify the models, bias is likely; nor are the usual variance calculations to be trusted. Here, we evaluate regression adjustments using Neyman's…

应用统计 · 统计学 2008-12-18 David A. Freedman

This article studies the behavior of regularized Tyler estimators (RTEs) of scatter matrices. The key advantages of these estimators are twofold. First, they guarantee by construction a good conditioning of the estimate and second, being a…

信息论 · 计算机科学 2016-04-20 Abla Kammoun , Romain Couillet , Frederic Pascal , Mohamed-Slim Alouini

Matching is a widely used causal inference design that aims to approximate a randomized experiment using observational data by forming matched sets of treated and control units based on similarities in their covariates. Ideally, treated…

统计方法学 · 统计学 2026-04-06 Jianan Zhu , Jeffrey Zhang , Zijian Guo , Siyu Heng
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