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This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

机器学习 · 计算机科学 2025-11-07 Anzhuo Xie , Wei-Chen Chang

The data available in Electronic Health Records (EHRs) provides the opportunity to transform care, and the best way to provide better care for one patient is through learning from the data available on all other patients. Temporal modelling…

计算与语言 · 计算机科学 2021-07-08 Zeljko Kraljevic , Anthony Shek , Daniel Bean , Rebecca Bendayan , James Teo , Richard Dobson

Predicting the incidence of complex chronic conditions such as heart failure is challenging. Deep learning models applied to rich electronic health records may improve prediction but remain unexplainable hampering their wider use in medical…

The early detection and prediction of cardiovascular diseases are crucial for reducing the severe morbidity and mortality associated with these conditions worldwide. A multi-headed self-attention mechanism, widely used in natural language…

Background: Electronic Health Records hold detailed longitudinal information about each patient's health status and general clinical history, a large portion of which is stored within the unstructured text. Existing approaches focus mostly…

Electronic Health Records (EHR) systematically organize patient health data through standardized medical codes, serving as a comprehensive and invaluable source for predictive modeling. Graph neural networks (GNNs) have demonstrated…

机器学习 · 计算机科学 2025-08-29 Haiyan Wang , Ye Yuan

To overcome the limitations of manual administrative coding in geriatric Cardiovascular Risk Management, this study introduces an automated classification framework leveraging unstructured Electronic Health Records (EHRs). Using a dataset…

Today, despite decades of developments in medicine and the growing interest in precision healthcare, vast majority of diagnoses happen once patients begin to show noticeable signs of illness. Early indication and detection of diseases,…

Transformer-based deep learning models have shown promise for disease risk prediction using electronic health records(EHRs), but modeling temporal dependencies remains a key challenge due to irregular visit intervals and lack of uniform…

机器学习 · 计算机科学 2025-11-10 Daniel S. Lee , Mayra S. Haedo-Cruz , Chen Jiang , Oshin Miranda , LiRong Wang

Understanding disease similarity is critical for advancing diagnostics, drug discovery, and personalized treatment strategies. We present PhenoGnet, a novel graph-based contrastive learning framework designed to predict disease similarity…

基因组学 · 定量生物学 2025-09-18 Ranga Baminiwatte , Kazi Jewel Rana , Aaron J. Masino

Identifying causative genes from patient phenotypes remains a significant challenge in precision medicine, with important implications for the diagnosis and treatment of genetic disorders. We propose a novel graph-based approach for…

机器学习 · 计算机科学 2025-06-17 Kamilia Zaripova , Ege Özsoy , Nassir Navab , Azade Farshad

Background: Artificial intelligence enabled electrocardiography (AI-ECG) has demonstrated the ability to detect diverse pathologies, but most existing models focus on single disease identification, neglecting comorbidities and future risk…

信号处理 · 电气工程与系统科学 2026-01-19 Jun Li , Hongling Zhu , Yujie Xiao , Qinghao Zhao , Yalei Ke , Gongzheng Tang , Guangkun Nie , Deyun Zhang , Jin Li , Canqing Yu , Shenda Hong

We hypothesize that large language models (LLMs) based on the transformer architecture can enable automated detection of clinical phenotype terms, including terms not documented in the HPO. In this study, we developed two types of models:…

定量方法 · 定量生物学 2023-11-10 Jingye Yang , Cong Liu , Wendy Deng , Da Wu , Chunhua Weng , Yunyun Zhou , Kai Wang

The widespread application of Electronic Health Records (EHR) data in the medical field has led to early successes in disease risk prediction using deep learning methods. These methods typically require extensive data for training due to…

机器学习 · 计算机科学 2024-11-28 Shibo Li , Hengliang Cheng , Weihua Li

Accurate extraction of breast cancer patients' phenotypes is important for clinical decision support and clinical research. Current models do not take full advantage of cancer domain-specific corpus, whether pre-training Bidirectional…

信息检索 · 计算机科学 2022-03-10 Sicheng Zhou , Liwei Wang , Nan Wang , Hongfang Liu , Rui Zhang

In this work, we propose a multi-task recurrent neural network with attention mechanism for predicting cardiovascular events from electronic health records (EHRs) at different time horizons. The proposed approach is compared to a standard…

A crucial step within secondary analysis of electronic health records (EHRs) is to identify the patient cohort under investigation. While EHRs contain medical billing codes that aim to represent the conditions and treatments patients may…

Electrocardiogram (ECG), a non-invasive and affordable tool for cardiac monitoring, is highly sensitive in detecting acute heart attacks. However, due to the lengthy nature of ECG recordings, numerous machine learning methods have been…

信号处理 · 电气工程与系统科学 2025-03-04 Yue Wang , Xu Cao , Yaojun Hu , Haochao Ying , Hongxia Xu , Ruijia Wu , James Matthew Rehg , Jimeng Sun , Jian Wu , Jintai Chen

Phenotyping electronic health records (EHR) focuses on defining meaningful patient groups (e.g., heart failure group and diabetes group) and identifying the temporal evolution of patients in those groups. Tensor factorization has been an…

Cardiovascular diseases (CVDs) remain a leading cause of mortality worldwide, underscoring the importance of accurate and scalable diagnostic systems. Electrocardiogram (ECG) analysis is central to detecting cardiac abnormalities, yet…

机器学习 · 计算机科学 2025-09-12 Md. Sajeebul Islam Sk. , Md Jobayer , Md Mehedi Hasan Shawon , Md. Golam Raibul Alam
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