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Synthetic medical data which preserves privacy while maintaining utility can be used as an alternative to real medical data, which has privacy costs and resource constraints associated with it. At present, most models focus on generating…

机器学习 · 计算机科学 2019-11-28 Saloni Dash , Ritik Dutta , Isabelle Guyon , Adrien Pavao , Andrew Yale , Kristin P. Bennett

We introduce the DP-auto-GAN framework for synthetic data generation, which combines the low dimensional representation of autoencoders with the flexibility of Generative Adversarial Networks (GANs). This framework can be used to take in…

机器学习 · 计算机科学 2020-12-11 Uthaipon Tantipongpipat , Chris Waites , Digvijay Boob , Amaresh Ankit Siva , Rachel Cummings

Clinical trials face mounting challenges: fragmented patient populations, slow enrollment, and unsustainable costs, particularly for late phase trials in oncology and rare diseases. While external control arms built from real-world data…

机器学习 · 计算机科学 2025-11-21 Perrine Chassat , Van Tuan Nguyen , Lucas Ducrot , Emilie Lanoy , Agathe Guilloux

Synthetic data has been hailed as the silver bullet for privacy preserving data analysis. If a record is not real, then how could it violate a person's privacy? In addition, deep-learning based generative models are employed successfully to…

机器学习 · 计算机科学 2023-07-14 Benedikt Groß , Gerhard Wunder

Machine learning heavily relies on data, but real-world applications often encounter various data-related issues. These include data of poor quality, insufficient data points leading to under-fitting of machine learning models, and…

High-quality training data is critical to the performance of machine learning models, particularly Large Language Models (LLMs). However, obtaining real, high-quality data can be challenging, especially for smaller organizations and…

机器学习 · 计算机科学 2025-06-24 Cristian Del Gobbo

Electronic Health Records (EHRs) are rich sources of patient-level data, offering valuable resources for medical data analysis. However, privacy concerns often restrict access to EHRs, hindering downstream analysis. Current EHR…

机器学习 · 计算机科学 2024-12-03 Muhang Tian , Bernie Chen , Allan Guo , Shiyi Jiang , Anru R. Zhang

Acquiring large quantities of data and annotations is known to be effective for developing high-performing deep learning models, but is difficult and expensive to do in the healthcare context. Adding synthetic training data using generative…

图像与视频处理 · 电气工程与系统科学 2023-10-06 Menghan Yu , Sourabh Kulhare , Courosh Mehanian , Charles B Delahunt , Daniel E Shea , Zohreh Laverriere , Ishan Shah , Matthew P Horning

Synthetic data generation (SDG) is a promising approach for enabling data sharing in biomedical studies while preserving patient privacy. Yet, state-of-the-art generative models often require large datasets and complex training procedures,…

机器学习 · 计算机科学 2026-01-27 Natalia Espinosa-Dice , Nicholas J. Jackson , Chao Yan , Aaron Lee , Bradley A. Malin

Background: Synthetic data has been proposed as a solution for sharing anonymized versions of sensitive biomedical datasets. Ideally, synthetic data should preserve the structure and statistical properties of the original data, while…

机器学习 · 计算机科学 2024-10-24 Ileana Montoya Perez , Parisa Movahedi , Valtteri Nieminen , Antti Airola , Tapio Pahikkala

Synthetic data from generative models emerges as the privacy-preserving data sharing solution. Such a synthetic data set shall resemble the original data without revealing identifiable private information. Till date, the prior focus on…

机器学习 · 计算机科学 2025-07-23 Chaoyi Zhu , Jiayi Tang , Juan F. Pérez , Marten van Dijk , Lydia Y. Chen

Due to privacy issues and limited amount of publicly available labeled datasets in the domain of medical imaging, we propose an image generation pipeline to synthesize 3D echocardiographic images with corresponding ground truth labels, to…

图像与视频处理 · 电气工程与系统科学 2024-03-11 Cristiana Tiago , Andrew Gilbert , Ahmed S. Beela , Svein Arne Aase , Sten Roar Snare , Jurica Sprem

In this work, we develop a privacy-by-design generative model for synthesizing the activity diary of the travel population using state-of-art deep learning approaches. This proposed approach extends literature on population synthesis by…

机器学习 · 计算机科学 2021-01-01 Godwin Badu-Marfo , Bilal Farooq , Zachary Patterson

Survival analysis studies time-modeling techniques for an event of interest occurring for a population. Survival analysis found widespread applications in healthcare, engineering, and social sciences. However, the data needed to train…

机器学习 · 计算机科学 2023-02-22 Alberto Archetti , Eugenio Lomurno , Francesco Lattari , André Martin , Matteo Matteucci

Synthetic data serves as an alternative in training machine learning models, particularly when real-world data is limited or inaccessible. However, ensuring that synthetic data mirrors the complex nuances of real-world data is a challenging…

机器学习 · 计算机科学 2023-10-27 Lasse Hansen , Nabeel Seedat , Mihaela van der Schaar , Andrija Petrovic

The use of synthetic data in health applications raises privacy concerns, yet the lack of open frameworks for privacy evaluations has slowed its adoption. A major challenge is the absence of accessible benchmark datasets for evaluating…

机器学习 · 计算机科学 2026-01-21 Bing Hu , Yixin Li , Asma Bahamyirou , Helen Chen

Survival analysis, time-to-event analysis, is an important problem in healthcare since it has a wide-ranging impact on patients and palliative care. Many survival analysis methods have assumed that the survival data is centrally available…

机器学习 · 计算机科学 2022-07-13 Md Mahmudur Rahman , Sanjay Purushotham

Recent years have witnessed a surge in the popularity of Machine Learning (ML), applied across diverse domains. However, progress is impeded by the scarcity of training data due to expensive acquisition and privacy legislation. Synthetic…

机器学习 · 计算机科学 2024-02-05 André Bauer , Simon Trapp , Michael Stenger , Robert Leppich , Samuel Kounev , Mark Leznik , Kyle Chard , Ian Foster

Deep learning in cardiac MRI (CMR) is fundamentally constrained by both data scarcity and privacy regulations. This study systematically benchmarks three generative architectures: Denoising Diffusion Probabilistic Models (DDPM), Latent…

计算机视觉与模式识别 · 计算机科学 2026-03-05 Madhura Edirisooriya , Dasuni Kawya , Ishan Kumarasinghe , Isuri Devindi , Mary M. Maleckar , Roshan Ragel , Isuru Nawinne , Vajira Thambawita

Synthetic data has gained significant momentum thanks to sophisticated machine learning tools that enable the synthesis of high-dimensional datasets. However, many generation techniques do not give the data controller control over what…