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Sepsis is a life-threatening condition defined by end-organ dysfunction due to a dysregulated host response to infection. Although the Surviving Sepsis Campaign has launched and has been releasing sepsis treatment guidelines to unify and…

机器学习 · 计算机科学 2024-11-20 Hyewon Jeong , Siddharth Nayak , Taylor Killian , Sanjat Kanjilal

Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…

机器学习 · 计算机科学 2025-02-07 Michelle M. Li , Kexin Huang , Marinka Zitnik

Reinforcement Learning in Healthcare is typically concerned with narrow self-contained tasks such as sepsis prediction or anesthesia control. However, previous research has demonstrated the potential of generalist models (the prime example…

机器学习 · 计算机科学 2024-05-28 Vadim Liventsev , Tobias Fritz

Deep learning methods exhibit promising performance for predictive modeling in healthcare, but two important challenges remain: -Data insufficiency:Often in healthcare predictive modeling, the sample size is insufficient for deep learning…

机器学习 · 计算机科学 2017-04-04 Edward Choi , Mohammad Taha Bahadori , Le Song , Walter F. Stewart , Jimeng Sun

Sepsis-induced acute respiratory failure (ARF) is a serious complication with a poor prognosis. This paper presents a deep representation learningbased phenotyping method to identify distinct groups of clinical trajectories of septic…

信号处理 · 电气工程与系统科学 2024-05-07 Alan Wu , Tilendra Choudhary , Pulakesh Upadhyaya , Ayman Ali , Philip Yang , Rishikesan Kamaleswaran

Sepsis is a leading cause of mortality in intensive care units (ICUs) and costs hospitals billions annually. Treating a septic patient is highly challenging, because individual patients respond very differently to medical interventions and…

机器学习 · 计算机科学 2017-05-24 Aniruddh Raghu , Matthieu Komorowski , Leo Anthony Celi , Peter Szolovits , Marzyeh Ghassemi

We propose a representation learning framework for medical diagnosis domain. It is based on heterogeneous network-based model of diagnostic data as well as modified metapath2vec algorithm for learning latent node representation. We compare…

机器学习 · 计算机科学 2020-01-24 Karol Antczak

Tailoring treatment for individual patients is crucial yet challenging in order to achieve optimal healthcare outcomes. Recent advances in reinforcement learning offer promising personalized treatment recommendations; however, they rely…

机器学习 · 计算机科学 2023-07-06 Simin Ma , Junghwan Lee , Nicoleta Serban , Shihao Yang

Recent recommender system advancements have focused on developing sequence-based and graph-based approaches. Both approaches proved useful in modeling intricate relationships within behavioral data, leading to promising outcomes in…

信息检索 · 计算机科学 2024-03-18 Vladimir Baikalov , Evgeny Frolov

Objective: Sepsis is a life-threatening condition caused by severe infection leading to acute organ dysfunction. This study proposes a data-driven metric and a continuous reward function to optimize personalized heparin therapy in surgical…

机器学习 · 计算机科学 2025-12-15 Jiang Liu , Yujie Li , Chan Zhou , Yihao Xie , Qilong Sun , Xin Shu , Peiwei Li , Chunyong Yang , Yiziting Zhu , Jiaqi Zhu , Yuwen Chen , Bo An , Hao Wu , Bin Yi

In the domain of semi-supervised learning, the current approaches insufficiently exploit the potential of considering inter-instance relationships among (un)labeled data. In this work, we address this limitation by providing an approach for…

机器学习 · 计算机科学 2023-10-17 Boshko Koloski , Nada Lavrač , Senja Pollak , Blaž Škrlj

Learning-based methods have become increasingly popular for solving vehicle routing problems due to their near-optimal performance and fast inference speed. Among them, the combination of deep reinforcement learning and graph representation…

机器学习 · 计算机科学 2024-05-22 Zhenwei Wang , Ruibin Bai , Fazlullah Khan , Ender Ozcan , Tiehua Zhang

Objective: Epilepsy is a chronic neurological disorder characterized by the occurrence of spontaneous seizures, which affects about one percent of the world's population. Most of the current seizure detection approaches strongly rely on…

信号处理 · 电气工程与系统科学 2020-02-04 Xiang Zhang , Lina Yao , Manqing Dong , Zhe Liu , Yu Zhang , Yong Li

Machine learning on graphs is an important and ubiquitous task with applications ranging from drug design to friendship recommendation in social networks. The primary challenge in this domain is finding a way to represent, or encode, graph…

社会与信息网络 · 计算机科学 2018-04-11 William L. Hamilton , Rex Ying , Jure Leskovec

In recent years, healthcare professionals are increasingly emphasizing on personalized and evidence-based patient care through the exploration of prognostic pathways. To study this, structured clinical variables from Electronic Health…

计算与语言 · 计算机科学 2025-09-16 Sudeshna Jana , Tirthankar Dasgupta , Lipika Dey

The disease trajectory for clinical sepsis, in terms of temporal cytokine and phenotypic dynamics, can be interpreted as a random dynamical system. The ability to make accurate predictions about patient state from clinical measurements has…

定量方法 · 定量生物学 2020-07-30 Dale Larie , Gary An , Chase Cockrell

Graphs or networks are a very convenient way to represent data with lots of interaction. Recently, Machine Learning on Graph data has gained a lot of traction. In particular, vertex classification and missing edge detection have very…

机器学习 · 计算机科学 2020-09-07 Simon Brandeis , Adrian Jarret , Pierre Sevestre

Evidence-based or data-driven dynamic treatment regimes are essential for personalized medicine, which can benefit from offline reinforcement learning (RL). Although massive healthcare data are available across medical institutions, they…

机器学习 · 统计学 2024-01-30 Doudou Zhou , Yufeng Zhang , Aaron Sonabend-W , Zhaoran Wang , Junwei Lu , Tianxi Cai

Sepsis is a deadly condition affecting many patients in the hospital. Recent studies have shown that patients diagnosed with sepsis have significant mortality and morbidity, resulting from the body's dysfunctional host response to…

机器学习 · 计算机科学 2022-12-14 Ronald Moore , Rishikesan Kamaleswaran

Reinforcement learning (RL) is a promising approach to generate treatment policies for sepsis patients in intensive care. While retrospective evaluation metrics show decreased mortality when these policies are followed, studies with…

机器学习 · 计算机科学 2024-04-11 Unnseo Park , Venkatesh Sivaraman , Adam Perer