相关论文: A comprehensive study on the characterization of l…
Significance: Quantitative measurement of blood oxygen saturation (sO$_2$) with photoacoustic (PA) imaging is one of the most sought after goals of quantitative PA imaging research due to its wide range of biomedical applications. Aim: A…
One of the main applications of photoacoustic (PA) imaging is the recovery of functional tissue properties, such as blood oxygenation (sO2). This is typically achieved by linear spectral unmixing of relevant chromophores from multispectral…
Multispectral photoacoustic (PA) imaging is a prime modality to monitor hemodynamics and changes in blood oxygenation (sO2). Although sO2 changes can be an indicator of brain activity both in normal and in pathological conditions, PA…
Spectroscopic photoacoustic (sPA) imaging can potentially estimate blood oxygenation saturation (sO2) in vivo noninvasively. However, quantitatively accurate results require accurate optical fluence estimates. Robust modeling in…
Optoacoustic (OA) imaging is a promising modality for quantifying blood oxygen saturation (sO$_2$) in various biomedical applications - in diagnosis, monitoring of organ function or even tumor treatment planning. We present an accurate and…
Several centimeters below the skin lie multiple biomarkers, such as glucose, oxygenation, and blood flow. Monitoring these biomarkers regularly and in a non-invasive manner would enable early insight into metabolic status and vascular…
A new approach for continuous and non-invasive monitoring of the glucose concentration in human epidermis has been suggested recently. This method is based on photoacoustic (PA) analysis of human interstitial fluid. The measurement can be…
A photoacoustic (PA) sensor for spectroscopic measurements of NO$_2$-N$_2$ at ambient pressure and temperature is demonstrated. The PA sensor is pumped resonantly by a nanosecond pulsed single-mode mid-infrared (MIR) optical parametric…
Photoacoustic (PA) imaging combines the high optical absorption contrast of optical imaging with the deep tissue penetration of ultrasound detection, offering great potential for functional imaging and disease diagnosis. However, current PA…
Significance: A path is described to increase the sensitivity and accuracy of body-worn devices used to monitor patient health. This path supports improved health management. A wavelength-choice algorithm developed at Mayo demonstrates that…
Anemia is a prevalent hematological disorder that requires frequent hemoglobin monitoring for early diagnosis and effective management. Conventional hemoglobin assessment relies on invasive blood sampling, limiting its suitability for…
Photoacoustic tomography (PAT) is intrinsically sensitive to blood oxygen saturation (sO2) in vivo. However, making accurate sO2 measurements without knowledge of tissue- and instrumentation-related correction factors is extremely…
This paper presents a practical guide to prepare inorganic solutions that mimic the photoacoustic properties of whole blood at specific levels of oxygenation in the range of 700 nm to 850 nm, both in terms of optical absorption properties…
Glycated hemoglobin (HbA1c) is the most important factor in diabetes control. Since HbA1c reflects the average blood glucose level over the preceding three months, it is unaffected by the patient's activity level or diet before the test.…
Continuous and noninvasive monitoring of blood pressure has numerous clinical and fitness applications. Current methods of continuous measurement of blood pressure are either invasive and/or require expensive equipment. Therefore, we…
We suggest a low cost, non invasive healthcare system that measures haemoglobin levels in patients and can be used as a preliminary diagnostic test for anaemia. A combination of image processing, machine learning and deep learning…
Non-invasive imaging of deep blood vessels for mapping hemodynamics remains an open quest in biomedical optical imaging. Although pure optical imaging techniques offer rich optical contrast of blood and have been reported to measure blood…
Optical imaging of blood flow yields critical functional insights into the circulatory system, but its clinical implementation has typically been limited to shallow depths (~1 millimeter) due to light scattering in biological tissue. Here,…
A numerical investigation of two-laser photoassociation (PA) spectroscopy on spin-polarized metastable helium (He*) atoms is presented within the context of experimental observation of the least-bound energy level in the scattering…
A photoacoustic (PA) sensor based on higher order acoustic modes is demonstrated. The PA sensor is designed to enhance the gas-detection performance and simultaneously suppress ambient noise sources (e.g. flow noise, electrical noise and…