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Renal pathology, as the gold standard of kidney disease diagnosis, requires doctors to analyze a series of tissue slices stained by H&E staining and special staining like Masson, PASM, and PAS, respectively. These special staining methods…

图像与视频处理 · 电气工程与系统科学 2023-09-19 Tao Ma , Chao Zhang , Min Lu , Lin Luo

Infrared and visible image fusion is a powerful technique that combines complementary information from different modalities for downstream semantic perception tasks. Existing learning-based methods show remarkable performance, but are…

计算机视觉与模式识别 · 计算机科学 2023-08-09 Zhu Liu , Jinyuan Liu , Benzhuang Zhang , Long Ma , Xin Fan , Risheng Liu

Pathology foundation models learn morphological representations through self-supervised pretraining on large-scale whole-slide images, yet they do not explicitly capture the underlying molecular state of the tissue. Spatial transcriptomics…

计算机视觉与模式识别 · 计算机科学 2026-03-10 Minsoo Lee , Jonghyun Kim , Juseung Yun , Sunwoo Yu , Jongseong Jang

Image registration under domain shift remains a fundamental challenge in computer vision and medical imaging: when source and target images exhibit systematic intensity differences, the brightness constancy assumption underlying…

计算机视觉与模式识别 · 计算机科学 2026-01-23 Jiahao Qin , Yiwen Wang

The hemorrhagic lesion segmentation plays a critical role in ophthalmic diagnosis, directly influencing early disease detection, treatment planning, and therapeutic efficacy evaluation. However, the task faces significant challenges due to…

计算机视觉与模式识别 · 计算机科学 2025-02-14 Zesheng Li , Minwen Liao , Haoran Chen , Yan Su , Chengchang Pan , Honggang Qi

Sensitivity to staining variation remains a major barrier to deploying computational pathology (CPath) models as hematoxylin and eosin (H&E) staining varies across laboratories, requiring systematic assessment of how this variability…

Hepatocellular carcinoma (HCC) is a common type of liver cancer whose early-stage diagnosis is a common challenge, mainly due to the manual assessment of hematoxylin and eosin-stained whole slide images, which is a time-consuming process…

图像与视频处理 · 电气工程与系统科学 2025-03-03 Ajinkya Deshpande , Deep Gupta , Ankit Bhurane , Nisha Meshram , Sneha Singh , Petia Radeva

Medical practitioners use a number of diagnostic tests to make a reliable diagnosis. Traditionally, Haematoxylin and Eosin (H&E) stained glass slides have been used for cancer diagnosis and tumor detection. However, recently a variety of…

图像与视频处理 · 电气工程与系统科学 2023-12-27 Abubakr Shafique , Morteza Babaie , Ricardo Gonzalez , H. R. Tizhoosh

Registration of serial whole-slide histopathological images (WSIs) is critical for enabling direct comparison across diverse stains and for preparing paired datasets in artificial intelligence (AI) workflows such as virtual staining and…

计算机视觉与模式识别 · 计算机科学 2025-09-04 Zeyu Liu , Shengwei Ding

Neural networks have changed the way machines interpret the world. At their core, they learn by following gradients, adjusting their parameters step by step until they identify the most discriminant patterns in the data. This process gives…

计算机视觉与模式识别 · 计算机科学 2025-11-03 Samarup Bhattacharya , Anubhab Bhattacharya , Abir Chakraborty

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

计算机视觉与模式识别 · 计算机科学 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

We present a scalable and efficient framework for the inference of spatially-varying parameters of continuum materials from image observations of their deformations. Our goal is the nondestructive identification of arbitrary damage,…

数值分析 · 数学 2024-08-21 Joseph Kirchhoff , Dingcheng Luo , Thomas O'Leary-Roseberry , Omar Ghattas

Accurate histopathological diagnosis often requires multiple differently stained tissue sections, a process that is time-consuming, labor-intensive, and environmentally taxing due to the use of multiple chemical stains. Recently, virtual…

计算机视觉与模式识别 · 计算机科学 2025-09-18 Jiabo MA , Wenqiang Li , Jinbang Li , Ziyi Liu , Linshan Wu , Fengtao Zhou , Li Liang , Ronald Cheong Kin Chan , Terence T. W. Wong , Hao Chen

Offline Handwritten Mathematical Expression Recognition (HMER) is a major area in the field of mathematical expression recognition. Offline HMER is often viewed as a much harder problem as compared to online HMER due to a lack of temporal…

计算机视觉与模式识别 · 计算机科学 2022-08-23 Ujjwal Thakur , Anuj Sharma

Many medical and biological protocols for analyzing individual biological cells involve morphological evaluation based on cell staining, designed to enhance imaging contrast and enable clinicians and biologists to differentiate between…

Recent studies have explored using pretrained Vision Foundation Models (VFMs) such as DINO for generative autoencoders, showing strong generative performance. Unfortunately, existing approaches often suffer from limited reconstruction…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Hun Chang , Byunghee Cha , Jong Chul Ye

We propose an unsupervised method using self-clustering convolutional adversarial autoencoders to classify prostate tissue as tumor or non-tumor without any labeled training data. The clustering method is integrated into the training of the…

计算机视觉与模式识别 · 计算机科学 2018-04-20 Wouter Bulten , Geert Litjens

Virtual stain transfer leverages computer-assisted technology to transform the histochemical staining patterns of tissue samples into other staining types. However, existing methods often lose detailed pathological information due to the…

计算机视觉与模式识别 · 计算机科学 2026-04-07 Haiyan Wei , Hangrui Xu , Bingxu Zhu , Yulian Geng , Aolei Liu , Wenfei Yin , Jian Liu

Three-dimensional X-ray histology techniques offer a non-invasive alternative to conventional 2D histology, enabling volumetric imaging of biological tissues without the need for physical sectioning or chemical staining. However, the…

图像与视频处理 · 电气工程与系统科学 2025-09-12 Sarah C. Irvine , Christian Lucas , Diana Krüger , Bianca Guedert , Julian Moosmann , Berit Zeller-Plumhoff

Staining is essential in cell imaging and medical diagnostics but poses significant challenges, including high cost, time consumption, labor intensity, and irreversible tissue alterations. Recent advances in deep learning have enabled…

计算机视觉与模式识别 · 计算机科学 2025-04-15 Ziwang Xu , Lanqing Guo , Satoshi Tsutsui , Shuyan Zhang , Alex C. Kot , Bihan Wen