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Although multi-instance learning (MIL) has succeeded in pathological image classification, it faces the challenge of high inference costs due to the need to process thousands of patches from each gigapixel whole slide image (WSI). To…

计算机视觉与模式识别 · 计算机科学 2025-08-08 Jiuyang Dong , Jiahan Li , Junjun Jiang , Kui Jiang , Yongbing Zhang

Studies estimate that there will be 266,120 new cases of invasive breast cancer and 40,920 breast cancer induced deaths in the year of 2018 alone. Despite the pervasiveness of this affliction, the current process to obtain an accurate…

计算机视觉与模式识别 · 计算机科学 2018-07-06 Siddhant Rao

The success of automated medical image analysis depends on large-scale and expert-annotated training sets. Unsupervised domain adaptation (UDA) has been raised as a promising approach to alleviate the burden of labeled data collection.…

计算机视觉与模式识别 · 计算机科学 2023-07-28 Jianan Fan , Dongnan Liu , Hang Chang , Heng Huang , Mei Chen , Weidong Cai

Multiple Instance Learning (MIL) has been widely applied in pathology towards solving critical problems such as automating cancer diagnosis and grading, predicting patient prognosis, and therapy response. Deploying these models in a…

计算机视觉与模式识别 · 计算机科学 2022-10-18 Syed Ashar Javed , Dinkar Juyal , Harshith Padigela , Amaro Taylor-Weiner , Limin Yu , Aaditya Prakash

Feature extraction techniques are crucial in medical image classification; however, classical feature extractors, in addition to traditional machine learning classifiers, often exhibit significant limitations in providing sufficient…

计算机视觉与模式识别 · 计算机科学 2025-10-01 Oscar Ramos-Soto , Jorge Ramos-Frutos , Ezequiel Perez-Zarate , Diego Oliva , Sandra E. Balderas-Mata

Histopathological prognostication of neoplasia including most tumor grading systems are based upon a number of criteria. Probably the most important is the number of mitotic figures which are most commonly determined as the mitotic count…

计算机视觉与模式识别 · 计算机科学 2020-01-06 Marc Aubreville , Christof A. Bertram , Robert Klopfleisch , Andreas Maier

High-quality annotated data plays a crucial role in achieving accurate segmentation. However, such data for medical image segmentation are often scarce due to the time-consuming and labor-intensive nature of manual annotation. To address…

计算机视觉与模式识别 · 计算机科学 2025-12-23 Zhanwei Li , Liang Li , Jiawan Zhang

Histopathological images are essential for medical diagnosis and treatment planning, but interpreting them accurately using machine learning can be challenging due to variations in tissue preparation, staining and imaging protocols. Domain…

计算机视觉与模式识别 · 计算机科学 2023-11-01 Vaibhav Khamankar , Sutanu Bera , Saumik Bhattacharya , Debashis Sen , Prabir Kumar Biswas

Preparing and scanning histopathology slides consists of several steps, each with a multitude of parameters. The parameters can vary between pathology labs and within the same lab over time, resulting in significant variability of the…

计算机视觉与模式识别 · 计算机科学 2018-01-11 Maxime W. Lafarge , Josien P. W. Pluim , Koen A. J. Eppenhof , Pim Moeskops , Mitko Veta

Anomaly detection aims to identify samples that deviate from the nominal data distribution and is central to many safety-critical applications. However, developing effective anomaly detection methods for categorical, mixed-type, and…

机器学习 · 计算机科学 2026-05-29 Lixing Zhang , Yuchen Liang , Liyan Xie

Multi-class cell nuclei detection is a fundamental prerequisite in the diagnosis of histopathology. It is critical to efficiently locate and identify cells with diverse morphology and distributions in digital pathological images. Most…

计算机视觉与模式识别 · 计算机科学 2023-10-24 Junjia Huang , Haofeng Li , Xiang Wan , Guanbin Li

Medical image segmentation poses challenges due to domain gaps, data modality variations, and dependency on domain knowledge or experts, especially for low- and middle-income countries (LMICs). Whereas for humans, given a few exemplars…

计算机视觉与模式识别 · 计算机科学 2024-10-28 Chen Xu , Qiming Huang , Yuqi Hou , Jiangxing Wu , Fan Zhang , Hyung Jin Chang , Jianbo Jiao

We present a summary of the domain adaptive cascade R-CNN method for mitosis detection of digital histopathology images. By comprehensive data augmentation and adapting existing popular detection architecture, our proposed method has…

图像与视频处理 · 电气工程与系统科学 2021-09-30 Xi Long , Ying Cheng , Xiao Mu , Lian Liu , Jingxin Liu

Background: Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide. Accurate survival prediction is essential for treatment stratification, yet existing pathology foundation models often overlook…

计算机视觉与模式识别 · 计算机科学 2026-04-15 Hikmat Khan , Usama Sajjad , Metin N. Gurcan , Anil Parwani , Wendy L. Frankel , Wei Chen , Muhammad Khalid Khan Niazi

Medical image analysis relies on accurate segmentation, and benefits from controllable synthesis (of new training images). Yet both tasks of the cyclical pipeline face spatial imbalance: lesions occupy small regions against vast…

计算机视觉与模式识别 · 计算机科学 2026-03-06 Anugunj Naman , Ayushman Singh , Gaibo Zhang , Yaguang Zhang

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

计算机视觉与模式识别 · 计算机科学 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr

Retinal artery/vein (A/V) classification is a critical technique for diagnosing diabetes and cardiovascular diseases. Although deep learning based methods achieve impressive results in A/V classification, their performances usually degrade…

计算机视觉与模式识别 · 计算机科学 2021-06-21 Chenxin Li , Yunlong Zhang , Zhehan Liang , Wenao Ma , Yue Huang , Xinghao Ding

The rapid evolution of malware variants requires robust classification methods to enhance cybersecurity. While Large Language Models (LLMs) offer potential for generating malware descriptions to aid family classification, their utility is…

密码学与安全 · 计算机科学 2025-05-01 Ivan Montoya Sanchez , Shaswata Mitra , Aritran Piplai , Sudip Mittal

Accurate delineation of individual cells in microscopy videos is essential for studying cellular dynamics, yet separating touching or overlapping instances remains a persistent challenge. Although foundation-model for segmentation such as…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Thomas Mendelson , Joshua Francois , Galit Lahav , Tammy Riklin-Raviv

Unsupervised domain adaptation object detection (UDAOD) research on Detection Transformer(DETR) mainly focuses on feature alignment and existing methods can be divided into two kinds, each of which has its unresolved issues. One-stage…

计算机视觉与模式识别 · 计算机科学 2024-01-19 Weixi Weng , Chun Yuan