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Cryo-electron microscopy (cryo-EM) allows for the high-resolution reconstruction of 3D structures of proteins and other biomolecules. Successful reconstruction of both shape and movement greatly helps understand the fundamental processes of…

计算机视觉与模式识别 · 计算机科学 2023-10-12 Xinhang Liu , Yan Zeng , Yifan Qin , Hao Li , Jiakai Zhang , Lan Xu , Jingyi Yu

Characterizing materials with electron micrographs is a crucial task in fields such as semiconductors and quantum materials. The complex hierarchical structure of micrographs often poses challenges for traditional classification methods. In…

计算机视觉与模式识别 · 计算机科学 2024-08-27 Sakhinana Sagar Srinivas , Geethan Sannidhi , Venkataramana Runkana

Understanding charts requires models to jointly reason over geometric visual patterns, structured numerical data, and natural language -- a capability where current vision-language models (VLMs) remain limited. We introduce ChartNet, a…

Electromagnetic (EM) sensing is a wide-spread contactless examination technique in science, engineering and military. However, conventional sensing systems are mostly lack of intelligence, which not only require expensive hardware and…

信号处理 · 电气工程与系统科学 2019-12-06 Hao-Yang Li , Han-Ting Zhao , Meng-Lin Wei , Heng-Xin Ruan , Ya Shuang , Tie Jun Cui , Lianlin Li

The promise of large-scale, high-resolution datasets from Electron Microscopy (EM) and X-ray Microtomography (XRM) lies in their ability to reveal neural structures and synaptic connectivity, which is critical for understanding the brain.…

This paper introduces M$^{3}$-20M, a large-scale Multi-Modal Molecule dataset that contains over 20 million molecules, with the data mainly being integrated from existing databases and partially generated by large language models. Designed…

定量方法 · 定量生物学 2025-03-18 Siyuan Guo , Lexuan Wang , Chang Jin , Jinxian Wang , Han Peng , Huayang Shi , Wengen Li , Jihong Guan , Shuigeng Zhou

While recent multimodal large language models (MLLMs) have advanced automated ECG interpretation, they still face two key limitations: (1) insufficient multimodal synergy between time series signals and visual ECG representations, and (2)…

计算与语言 · 计算机科学 2025-10-21 Xiang Lan , Feng Wu , Kai He , Qinghao Zhao , Shenda Hong , Mengling Feng

Significant advancements in Large Multimodal Models (LMMs) have enabled them to tackle complex problems involving visual-mathematical reasoning. However, their ability to identify geometric elements remains underexplored. To address this…

计算机视觉与模式识别 · 计算机科学 2024-12-18 Chao Zhang , Jiamin Tang , Jing Xiao

Cryo-Electron Microscopy (cryo-EM) has emerged as a key technology to determine the structure of proteins, particularly large protein complexes and assemblies in recent years. A key challenge in cryo-EM data analysis is to automatically…

生物大分子 · 定量生物学 2023-04-04 Nabin Giri , Raj S. Roy , Jianlin Cheng

Recently, a growing interest has been seen in deep learning-based semantic segmentation. UNet, which is one of deep learning networks with an encoder-decoder architecture, is widely used in medical image segmentation. Combining multi-scale…

图像与视频处理 · 电气工程与系统科学 2020-04-21 Huimin Huang , Lanfen Lin , Ruofeng Tong , Hongjie Hu , Qiaowei Zhang , Yutaro Iwamoto , Xianhua Han , Yen-Wei Chen , Jian Wu

Automated experimentation with real time data analysis in scanning transmission electron microscopy (STEM) often require end-to-end framework. The four-dimensional scanning transmission electron microscopy (4D-STEM) with high-throughput…

计算机视觉与模式识别 · 计算机科学 2025-08-26 Mingyu Liu , Zian Mao , Zhu Liu , Haoran Zhang , Jintao Guo , Xiaoya He , Xi Huang , Shufen Chu , Chun Cheng , Jun Ding , Yujun Xie

Over the past decade, cryogenic electron microscopy (cryo-EM) has emerged as a primary method for determining near-native, near-atomic resolution 3D structures of biological macromolecules. In order to meet increasing demand for cryo-EM,…

图像与视频处理 · 电气工程与系统科学 2022-01-19 Paul T. Kim , Alex J. Noble , Anchi Cheng , Tristan Bepler

Transmission Electron Microscopy (TEM) is a powerful tool for imaging material structure and characterizing material chemistry. Recent advances in data collection technology for TEM have enabled high-volume and high-resolution data…

计算机视觉与模式识别 · 计算机科学 2021-08-24 Josh Kacher , Yao Xie , Sven P. Voigt , Shixiang Zhu , Henry Yuchi , Jordan Key , Surya R. Kalidindi

Transductive few-shot learning has recently triggered wide attention in computer vision. Yet, current methods introduce key hyper-parameters, which control the prediction statistics of the test batches, such as the level of class balance,…

计算机视觉与模式识别 · 计算机科学 2025-04-14 Long Zhou , Fereshteh Shakeri , Aymen Sadraoui , Mounir Kaaniche , Jean-Christophe Pesquet , Ismail Ben Ayed

A unified and versatile LiDAR segmentation model with strong robustness and generalizability is desirable for safe autonomous driving perception. This work presents M3Net, a one-of-a-kind framework for fulfilling multi-task, multi-dataset,…

计算机视觉与模式识别 · 计算机科学 2024-05-03 Youquan Liu , Lingdong Kong , Xiaoyang Wu , Runnan Chen , Xin Li , Liang Pan , Ziwei Liu , Yuexin Ma

In light of globalized hardware supply chains, the assurance of hardware components has gained significant interest, particularly in cryptographic applications and high-stakes scenarios. Identifying metal lines on scanning electron…

密码学与安全 · 计算机科学 2026-03-18 Christian Gehrmann , Jonas Ricker , Simon Damm , Deruo Cheng , Julian Speith , Yiqiong Shi , Asja Fischer , Christof Paar

Cryo-EM is a transformational paradigm in molecular biology where computational methods are used to infer 3D molecular structure at atomic resolution from extremely noisy 2D electron microscope images. At the forefront of research is how to…

定量方法 · 定量生物学 2025-06-12 Shayan Shekarforoush , David B. Lindell , Marcus A. Brubaker , David J. Fleet

Electron microscopy (EM) images exhibit anisotropic axial resolution due to the characteristics inherent to the imaging modality, presenting challenges in analysis and downstream tasks.In this paper, we propose a diffusion-model-based…

计算机视觉与模式识别 · 计算机科学 2023-08-04 Kyungryun Lee , Won-Ki Jeong

Differentiating signals from the background in micrographs is a critical initial step for cryogenic electron microscopy (cryo-EM), yet it remains laborious due to low signal-to-noise ratio (SNR), the presence of contaminants and densely…

图像与视频处理 · 电气工程与系统科学 2025-09-30 Szu-Chi Chung , Po-Cheng Chou

A single-particle cryo-electron microscopy (cryo-EM) measurement, called a micrograph, consists of multiple two-dimensional tomographic projections of a three-dimensional (3-D) molecular structure at unknown locations, taken under unknown…

图像与视频处理 · 电气工程与系统科学 2026-03-10 Shay Kreymer , Amit Singer , Tamir Bendory