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Improving the ability to predict protein function can potentially facilitate research in the fields of drug discovery and precision medicine. Technically, the properties of proteins are directly or indirectly reflected in their sequence and…

生物大分子 · 定量生物学 2024-11-19 Runze Ma , Chengxin He , Huiru Zheng , Xinye Wang , Haiying Wang , Yidan Zhang , Lei Duan

Classification and identification of wild animals for tracking and protection purposes has become increasingly important with the deterioration of the environment, and technology is the agent of change which augments this process with novel…

计算机视觉与模式识别 · 计算机科学 2022-10-17 Sahil Faizal , Sanjay Sundaresan

Understanding and predicting video content is essential for planning and reasoning in dynamic environments. Despite advancements, unsupervised learning of object representations and dynamics remains challenging. We present VideoPCDNet, an…

计算机视觉与模式识别 · 计算机科学 2025-06-25 Noel José Rodrigues Vicente , Enrique Lehner , Angel Villar-Corrales , Jan Nogga , Sven Behnke

In this work we set out to find a method to classify protein structures using a Deep Learning methodology. Our Artificial Intelligence has been trained to recognize complex biomolecule structures extrapolated from the Protein Data Bank…

机器学习 · 计算机科学 2021-11-04 Damiano Perri , Marco Simonetti , Andrea Lombardi , Noelia Faginas-Lago , Osvaldo Gervasi

While Prover-Verifier Games (PVGs) offer a promising path toward verifiability in nonlinear classification models, they have not yet been applied to complex inputs such as high-dimensional images. Conversely, expressive concept encodings…

Photoplethysmography (PPG) signals encode information about relative changes in blood volume that can be used to assess various aspects of cardiac health non-invasively, e.g.\ to detect atrial fibrillation (AF) or predict blood pressure…

机器学习 · 计算机科学 2025-05-19 Ciaran Bench , Vivek Desai , Mohammad Moulaeifard , Nils Strodthoff , Philip Aston , Andrew Thompson

Proteins perform much of the work in living organisms, and consequently the development of efficient computational methods for protein representation is essential for advancing large-scale biological research. Most current approaches…

定量方法 · 定量生物学 2023-06-09 Francesco Ceccarelli , Lorenzo Giusti , Sean B. Holden , Pietro Liò

We present PredProp, a method for optimization of weights and states in predictive coding networks (PCNs) based on the precision of propagated errors and neural activity. PredProp jointly addresses inference and learning via stochastic…

机器学习 · 计算机科学 2023-05-08 André Ofner , Sebastian Stober

Among steganalysis techniques, detection against motion vector (MV) domain-based video steganography in High Efficiency Video Coding (HEVC) standard remains a hot and challenging issue. For the purpose of improving the detection…

密码学与安全 · 计算机科学 2023-08-15 Jun Li , Minqing Zhang , Ke Niu , Yingnan Zhang , Xiaoyuan Yang

Protein function prediction is a crucial task in bioinformatics, with significant implications for understanding biological processes and disease mechanisms. While the relationship between sequence and function has been extensively…

定量方法 · 定量生物学 2024-09-04 Shania Mitra , Lei Huang , Manolis Kellis

Understanding the dynamic nature of protein structures is essential for comprehending their biological functions. While significant progress has been made in predicting static folded structures, modeling protein motions on microsecond to…

Shotgun proteomics is a high-throughput technology used to identify unknown proteins in a complex mixture. At the heart of this process is a prediction task, the spectrum identification problem, in which each fragmentation spectrum produced…

计算工程、金融与科学 · 计算机科学 2012-10-19 Ajit P. Singh , John Halloran , Jeff A. Bilmes , Katrin Kirchoff , William S. Noble

Partial differential equations (PDEs) play a fundamental role in modeling and simulating problems across a wide range of disciplines. Recent advances in deep learning have shown the great potential of physics-informed neural networks…

机器学习 · 计算机科学 2022-01-31 Pu Ren , Chengping Rao , Yang Liu , Jianxun Wang , Hao Sun

The Computer_Aided Diagnosis (CAD) systems facilitate accurate diagnosis of diseases. The development of CADs by leveraging third generation neural network, namely, Spiking Neural Network (SNN), is essential to utilize of the benefits of…

图像与视频处理 · 电气工程与系统科学 2025-04-28 Mohaddeseh Chegini , Ali Mahloojifar

In material science, image segmentation is of great significance for quantitative analysis of microstructures. Here, we propose a novel Weighted Propagation Convolution Neural Network based on U-Net (WPU-Net) to detect boundary in…

计算机视觉与模式识别 · 计算机科学 2025-07-11 Wei Liu , Jiahao Chen , Chuni Liu , Xiaojuan Ban , Boyuan Ma , Hao Wang , Weihua Xue , Yu Guo

In recent years, the scientific community has focused on the development of CAD tools that could improve bone fractures' classification, mostly based on Convolutional Neural Network (CNN). However, the discerning accuracy of fractures'…

人工智能 · 计算机科学 2021-10-27 Leonardo Tanzi , Andrea Audisio , Giansalvo Cirrincione , Alessandro Aprato , Enrico Vezzetti

The ability to accurately model the fitness landscape of protein sequences is critical to a wide range of applications, from quantifying the effects of human variants on disease likelihood, to predicting immune-escape mutations in viruses…

Machine learning methods such as convolutional neural networks (CNNs) are becoming an integral part of scientific research in many disciplines, spatial vector data often fail to be analyzed using these powerful learning methods because of…

机器学习 · 统计学 2018-09-24 Xiongfeng Yan , Tinghua Ai

The past decade has witnessed great success of deep learning technology in many disciplines, especially in computer vision and image processing. However, deep learning-based video coding remains in its infancy. This paper reviews the…

多媒体 · 计算机科学 2020-03-13 Dong Liu , Yue Li , Jianping Lin , Houqiang Li , Feng Wu

Cancer is a complex disease characterized by uncontrolled cell growth. T cell receptors (TCRs), crucial proteins in the immune system, play a key role in recognizing antigens, including those associated with cancer. Recent advancements in…

机器学习 · 计算机科学 2025-06-12 Taslim Murad , Prakash Chourasia , Sarwan Ali , Imdad Ullah Khan , Murray Patterson