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We present a simple, modular graph-based convolutional neural network that takes structural information from protein-ligand complexes as input to generate models for activity and binding mode prediction. Complex structures are generated by…

生物大分子 · 定量生物学 2020-02-26 Joseph A. Morrone , Jeffrey K. Weber , Tien Huynh , Heng Luo , Wendy D. Cornell

In convolutional neural networks (CNNs), padding plays a pivotal role in preserving spatial dimensions throughout the layers. Traditional padding techniques do not explicitly distinguish between the actual image content and the padded…

计算机视觉与模式识别 · 计算机科学 2023-11-20 Juho Kim

As a representative of a new generation of biometrics, vein identification technology offers a high level of security and convenience.Convolutional neural networks (CNNs), a prominent class of deep learning architectures, have been…

计算机视觉与模式识别 · 计算机科学 2024-10-15 Xin Jin , Hongyu Zhu , Mounîm A. El Yacoubi , Haiyang Li , Hongchao Liao , Huafeng Qin , Yun Jiang

As an important part of linear perspective, vanishing points (VPs) provide useful clues for mapping objects from 2D photos to 3D space. Existing methods are mainly focused on extracting structural features such as lines or contours and then…

计算机视觉与模式识别 · 计算机科学 2020-06-11 Yin-Bo Liu , Ming Zeng , Qing-Hao Meng

This paper presents PreVIous, a methodology to predict the performance of convolutional neural networks (CNNs) in terms of throughput and energy consumption on vision-enabled devices for the Internet of Things. CNNs typically constitute a…

计算机视觉与模式识别 · 计算机科学 2020-03-18 Delia Velasco-Montero , Jorge Fernández-Berni , Ricardo Carmona-Galán , Ángel Rodríguez-Vázquez

Systematic identification of protein function is a key problem in current biology. Most traditional methods fail to identify functionally equivalent proteins if they lack similar sequences, structural data or extensive manual annotations.…

基因组学 · 定量生物学 2016-03-08 Dan Ofer

Deep convolutional neural networks (CNNs) have delivered superior performance in many computer vision tasks. In this paper, we propose a novel deep fully convolutional network model for accurate salient object detection. The key…

计算机视觉与模式识别 · 计算机科学 2017-08-08 Pingping Zhang , Dong Wang , Huchuan Lu , Hongyu Wang , Baocai Yin

Cell-level dense prediction is central to computational pathology, but remains challenging due to fine-grained histological structures, strong domain shifts, and costly dense annotations. Existing ViT-based pathology foundation models rely…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Weiming Chen , Xitong Ling , Zhenyang Cai , Xidong Wang , Jiawen Li , Tian Guan , Benyou Wang , Yonghong He

Recently developed deep learning techniques have significantly improved the accuracy of various speech and image recognition systems. In this paper we adapt some of these techniques for protein secondary structure prediction. We first train…

机器学习 · 计算机科学 2016-11-07 Akosua Busia , Jasmine Collins , Navdeep Jaitly

Deep convolutional neural networks are used to address many computer vision problems, including video prediction. The task of video prediction requires analyzing the video frames, temporally and spatially, and constructing a model of how…

计算机视觉与模式识别 · 计算机科学 2018-10-17 Niloofar Azizi , Hafez Farazi , Sven Behnke

Motivation: In recent years, protein function prediction has broken through the bottleneck of sequence features, significantly improving prediction accuracy using high-precision protein structures predicted by AlphaFold2. While…

机器学习 · 计算机科学 2025-04-01 Beibei Wang , Boyue Cui , Shiqu Chen , Xuan Wang , Yadong Wang , Junyi Li

As proteins with similar structures often have similar functions, analysis of protein structures can help predict protein functions and is thus important. We consider the problem of protein structure classification, which computationally…

机器学习 · 统计学 2019-10-08 Hongyu Guo , Khalique Newaz , Scott Emrich , Tijana Milenkovic , Jun Li

The black-box nature of Convolutional Neural Networks (CNNs) and their reliance on large datasets limit their use in complex domains with limited labeled data. Physics-Guided Neural Networks (PGNNs) have emerged to address these limitations…

计算机视觉与模式识别 · 计算机科学 2024-09-04 Kishor Datta Gupta , Marufa Kamal , Rakib Hossain Rifat , Mohd Ariful Haque , Roy George

Deep convolutional neural networks (CNNs) have proven highly effective for visual recognition, where learning a universal representation from activations of convolutional layer plays a fundamental problem. In this paper, we present Fisher…

计算机视觉与模式识别 · 计算机科学 2016-11-30 Zhaofan Qiu , Ting Yao , Tao Mei

Emerging deep-learning (DL)-based techniques have significant potential to revolutionize biomedical imaging. However, one outstanding challenge is the lack of reliability assessment in the DL predictions, whose errors are commonly revealed…

图像与视频处理 · 电气工程与系统科学 2019-05-07 Yujia Xue , Shiyi Cheng , Yunzhe Li , Lei Tian

Predicting protein properties, functions and localizations are important tasks in bioinformatics. Recent progress in machine learning offers an opportunities for improving existing methods. We developed a new approach called ProtBoost,…

定量方法 · 定量生物学 2024-12-09 Alexander Chervov , Anton Vakhrushev , Sergei Fironov , Loredana Martignetti

This paper has proposed a new baseline deep learning model of more benefits for image classification. Different from the convolutional neural network(CNN) practice where filters are trained by back propagation to represent different…

计算机视觉与模式识别 · 计算机科学 2021-08-13 Yifei Li , Kuangyan Song , Yiming Sun , Liao Zhu

Background and objective: Uncertainty quantification is a pivotal field that contributes to realizing reliable and robust systems. It becomes instrumental in fortifying safe decisions by providing complementary information, particularly…

图像与视频处理 · 电气工程与系统科学 2024-03-19 Jamil Fayyad , Shadi Alijani , Homayoun Najjaran

Deep neural networks (DNNs) have been showed to be highly vulnerable to imperceptible adversarial perturbations. As a complementary type of adversary, patch attacks that introduce perceptible perturbations to the images have attracted the…

计算机视觉与模式识别 · 计算机科学 2023-07-04 Zhaoyu Chen , Bo Li , Shuang Wu , Shouhong Ding , Wenqiang Zhang

Many applications of machine learning methods involve an iterative protocol in which data are collected, a model is trained, and then outputs of that model are used to choose what data to consider next. For example, one data-driven approach…