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Breast cancer is one of the leading cancers for women in developed countries including India. It is the second most common cause of cancer death in women. The high incidence of breast cancer in women has increased significantly in the last…

数据库 · 计算机科学 2012-05-10 Shweta Kharya

We discuss a shift in perspective from traditional approaches to breast cancer risk prediction: modelling families rather than individuals as unit of analysis. By investigating the latent familial risk underlying breast cancer diagnoses, we…

应用统计 · 统计学 2025-08-25 Maria Veronica Vinattieri , Marco Bonetti , Kamila Czene

The development of accessible screening tools for early cancer detection in dogs represents a significant challenge in veterinary medicine. Routine laboratory data offer a promising, low-cost source for such tools, but their utility is…

机器学习 · 计算机科学 2025-12-11 Shumin Li

Breast cancer patients may experience relapse or death after surgery during the follow-up period, leading to dependent censoring of relapse. This phenomenon, known as semi-competing risk, imposes challenges in analyzing treatment effects on…

统计方法学 · 统计学 2024-07-03 Tonghui Yu , Mengjiao Peng , Yifan Cui , Elynn Chen , Chixiang Chen

Understanding the factors that explain differences in survival times is an important issue for establishing policies to improve national health systems. Motivated by breast cancer data arising from the Surveillance Epidemiology and End…

应用统计 · 统计学 2015-05-13 Haiming Zhou , Timothy Hanson , Alejandro Jara , Jiajia Zhang

Recently, several classifiers that combine primary tumor data, like gene expression data, and secondary data sources, such as protein-protein interaction networks, have been proposed for predicting outcome in breast cancer. In these…

机器学习 · 计算机科学 2013-10-15 C. Staiger , S. Cadot , R. Kooter , M. Dittrich , T. Mueller , G. W. Klau , L. F. A. Wessels

Often, a community becomes alarmed when high rates of cancer are noticed, and residents suspect that the cancer cases could be caused by a known source of hazard. In response, the CDC recommends that departments of health perform a…

统计方法学 · 统计学 2018-12-12 Rachel C. Nethery , Yue Yang , Anna J. Brown , Francesca Dominici

Accurate estimation of cancer mortality rates and the comparison across cancer sites, populations or time periods is crucial to public health, as identification of vulnerable groups who suffer the most from these diseases may lead to…

统计方法学 · 统计学 2014-01-31 Martina Fu , David Todem , Wenjiang J. Fu , Shuangge Ma

This study investigates the interplay among social demographics, built environment characteristics, and environmental hazard exposure features in determining community level cancer prevalence. Utilizing data from five Metropolitan…

机器学习 · 计算机科学 2023-06-26 Chenyue Liu , Ali Mostafavi

Correctly assessing the malignancy of breast lesions identified during ultrasound examinations is crucial for effective clinical decision-making. However, the current "golden standard" relies on manual BI-RADS scoring by clinicians, often…

机器学习 · 计算机科学 2024-08-29 Alek Fröhlich , Thiago Ramos , Gustavo Cabello , Isabela Buzatto , Rafael Izbicki , Daniel Tiezzi

Non-muscle-invasive bladder cancer (NMIBC) is a relentless challenge in oncology, with recurrence rates soaring as high as 70-80%. Each recurrence triggers a cascade of invasive procedures, lifelong surveillance, and escalating healthcare…

机器学习 · 计算机科学 2025-05-02 Saram Abbas , Naeem Soomro , Rishad Shafik , Rakesh Heer , Kabita Adhikari

We propose a new methodology for selecting and ranking covariates associated with a variable of interest in a context of high-dimensional data under dependence but few observations. The methodology successively intertwines the clustering of…

With medical tests becoming increasingly available, concerns about over-testing and over-treatment dramatically increase. Hence, it is important to understand the influence of testing on treatment selection in general practice. Most…

统计方法学 · 统计学 2020-08-11 Yun Li , Irina Bondarenko , Michael R. Elliott , Timothy P. Hofer , Jeremy M. G. Taylor

Strategies to prevent cancer and diagnose it early when it is most treatable are needed to reduce the public health burden from rising disease incidence. Risk assessment is playing an increasingly important role in targeting individuals in…

应用统计 · 统计学 2020-03-09 Adam R Brentnall , Jack Cuzick

Motivated by the pressing need for suicide prevention through improving behavioral healthcare, we use medical claims data to study the risk of subsequent suicide attempts for patients who were hospitalized due to suicide attempts and later…

应用统计 · 统计学 2023-05-09 Wenjie Wang , Chongliang Luo , Robert H. Aseltine , Fei Wang , Jun Yan , Kun Chen

Breast Cancer is the most common cancer among women, which is also visible in men, and accounts for more than 1 in 10 new cancer diagnoses each year. It is also the second most common cause of women who die from cancer. Hence, it…

图像与视频处理 · 电气工程与系统科学 2023-10-17 Kanan Mahammadli , Abdullah Burkan Bereketoglu , Ayse Gul Kabakci

BACKGROUND: Breast cancer has emerged as one of the most prevalent cancers among women leading to a high mortality rate. Due to the heterogeneous nature of breast cancer, there is a need to identify differentially expressed genes associated…

机器学习 · 计算机科学 2021-11-30 Sheetal Rajpal , Ankit Rajpal , Manoj Agarwal , Naveen Kumar

Mammographic breast density, a parameter used to describe the proportion of breast tissue fibrosis, is widely adopted as an evaluation characteristic of the likelihood of breast cancer incidence. In this study, we present a radiomics…

计算机视觉与模式识别 · 计算机科学 2018-09-28 Jingxu Xu , Cheng Li , Yongjin Zhou , Lisha Mou , Hairong Zheng , Shanshan Wang

Despite initial success, cancer therapies often fail due to the emergence of drug-resistant cells. In this study, we use a mathematical model to investigate how cancer evolves over time, specifically focusing on the state of the tumor when…

概率论 · 数学 2023-08-01 Kevin Leder , Zicheng Wang

Multi-gene panel testing allows many cancer susceptibility genes to be tested quickly at a lower cost making such testing accessible to a broader population. Thus, more patients carrying pathogenic germline mutations in various…

统计方法学 · 统计学 2023-06-13 Thanthirige Lakshika M. Ruberu , Danielle Braun , Giovanni Parmigiani , Swati Biswas