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Multiple instance learning (MIL) stands as a powerful approach in weakly supervised learning, regularly employed in histological whole slide image (WSI) classification for detecting tumorous lesions. However, existing mainstream MIL methods…

图像与视频处理 · 电气工程与系统科学 2024-07-08 Wenhui Zhu , Xiwen Chen , Peijie Qiu , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang

We address the problem of \emph{instance label stability} in multiple instance learning (MIL) classifiers. These classifiers are trained only on globally annotated images (bags), but often can provide fine-grained annotations for image…

计算机视觉与模式识别 · 计算机科学 2017-03-16 Veronika Cheplygina , Lauge Sørensen , David M. J. Tax , Marleen de Bruijne , Marco Loog

Multi-instance learning (MIL) has a wide range of applications due to its distinctive characteristics. Although many state-of-the-art algorithms have achieved decent performances, a plurality of existing methods solve the problem only in…

机器学习 · 统计学 2015-12-04 Hanqiang Song , Zhuotun Zhu , Xinggang Wang

Continual learning is essential for medical image classification systems to adapt to dynamically evolving clinical environments. The integration of multimodal information can significantly enhance continual learning of image classes.…

计算机视觉与模式识别 · 计算机科学 2025-08-06 Jiantao Tan , Peixian Ma , Kanghao Chen , Zhiming Dai , Ruixuan Wang

Multiple instance learning (MIL) problem is currently solved from either bag-classification or instance-classification perspective, both of which ignore important information contained in some instances and result in limited performance.…

计算机视觉与模式识别 · 计算机科学 2024-08-12 Yingfan Ma , Xiaoyuan Luo , Mingzhi Yuan , Xinrong Chen , Manning Wang

Multiple Instance Learning (MIL) plays a significant role in computational pathology, enabling weakly supervised analysis of Whole Slide Image (WSI) datasets. The field of WSI analysis is confronted with a severe long-tailed distribution…

计算机视觉与模式识别 · 计算机科学 2025-03-04 Xitong Ling , Yifeng Ping , Jiawen Li , Jing Peng , Yuxuan Chen , Minxi Ouyang , Yizhi Wang , Yonghong He , Tian Guan , Xiaoping Liu , Lianghui Zhu

The current medical standard for setting an oral cancer (OC) diagnosis is histological examination of a tissue sample from the oral cavity. This process is time consuming and more invasive than an alternative approach of acquiring a brush…

图像与视频处理 · 电气工程与系统科学 2022-02-07 Nadezhda Koriakina , Nataša Sladoje , Vladimir Bašić , Joakim Lindblad

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Timely and accurate lymphoma diagnosis is essential for guiding cancer treatment. Standard diagnostic practice combines hematoxylin and eosin (HE)-stained whole slide images with immunohistochemistry, flow cytometry, and molecular genetic…

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

计算机视觉与模式识别 · 计算机科学 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

Multi-instance learning (MIL) is a widely-applied technique in practical applications that involve complex data structures. MIL can be broadly categorized into two types: traditional methods and those based on deep learning. These…

人工智能 · 计算机科学 2023-04-25 Yu-Xuan Zhang , Zhengchun Zhou , Xingxing He , Avik Ranjan Adhikary , Bapi Dutta

Learning representations for individual instances when only bag-level labels are available is a fundamental challenge in multiple instance learning (MIL). Recent works have shown promising results using contrastive self-supervised learning…

计算机视觉与模式识别 · 计算机科学 2023-07-13 Kangning Liu , Weicheng Zhu , Yiqiu Shen , Sheng Liu , Narges Razavian , Krzysztof J. Geras , Carlos Fernandez-Granda

Multiple instance learning (MIL) can reduce the need for costly annotation in tasks such as semantic segmentation by weakening the required degree of supervision. We propose a novel MIL formulation of multi-class semantic segmentation…

计算机视觉与模式识别 · 计算机科学 2015-04-16 Deepak Pathak , Evan Shelhamer , Jonathan Long , Trevor Darrell

Continual learning (CL) refers to a machine learning paradigm that learns continuously without forgetting previously acquired knowledge. Thereby, major difficulty in CL is catastrophic forgetting of preceding tasks, caused by shifts in data…

机器学习 · 计算机科学 2023-03-08 Stella Ho , Ming Liu , Lan Du , Longxiang Gao , Yong Xiang

Leukemia, the cancer of blood cells, originates in the blood-forming cells of the bone marrow. In Chronic Myeloid Leukemia (CML) conditions, the cells partially become mature that look like normal white blood cells but do not resist…

基因组学 · 定量生物学 2023-02-09 Madiha Hameed , Muhammad Bilal , Tuba Majid , Abdul Majid , Asifullah Khan

Whole slide image (WSI) assessment is a challenging and crucial step in cancer diagnosis and treatment planning. WSIs require high magnifications to facilitate sub-cellular analysis. Precise annotations for patch- or even pixel-level…

计算机视觉与模式识别 · 计算机科学 2023-11-20 Simon Holdenried-Krafft , Peter Somers , Ivonne A. Montes-Majarro , Diana Silimon , Cristina Tarín , Falko Fend , Hendrik P. A. Lensch

Continual learning (CL) aims to empower machine learning models to learn continually from new data, while building upon previously acquired knowledge without forgetting. As models have evolved from small to large pre-trained architectures,…

机器学习 · 计算机科学 2026-03-31 Dianzhi Yu , Xinni Zhang , Yankai Chen , Aiwei Liu , Yifei Zhang , Philip S. Yu , Irwin King

Multi-Instance Learning (MIL) has shown impressive performance for histopathology whole slide image (WSI) analysis using bags or pseudo-bags. It involves instance sampling, feature representation, and decision-making. However, existing…

计算机视觉与模式识别 · 计算机科学 2024-03-14 Tingting Zheng , Kui Jiang , Hongxun Yao

Being able to learn on weakly labeled data, and provide interpretability, are two of the main reasons why attention-based deep multiple instance learning (ABMIL) methods have become particularly popular for classification of…

计算机视觉与模式识别 · 计算机科学 2022-03-09 Axel Andersson , Nadezhda Koriakina , Nataša Sladoje , Joakim Lindblad

Multiple Instance Learning (MIL) has demonstrated promise in Whole Slide Image (WSI) classification. However, a major challenge persists due to the high computational cost associated with processing these gigapixel images. Existing methods…

计算机视觉与模式识别 · 计算机科学 2023-12-05 Hongyi Wang , Luyang Luo , Fang Wang , Ruofeng Tong , Yen-Wei Chen , Hongjie Hu , Lanfen Lin , Hao Chen