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Understanding disease similarity is critical for advancing diagnostics, drug discovery, and personalized treatment strategies. We present PhenoGnet, a novel graph-based contrastive learning framework designed to predict disease similarity…

基因组学 · 定量生物学 2025-09-18 Ranga Baminiwatte , Kazi Jewel Rana , Aaron J. Masino

While there have been many studies on hardware acceleration for deep learning on images, there has been a rather limited focus on accelerating deep learning applications involving graphs. The unique characteristics of graphs, such as the…

机器学习 · 计算机科学 2021-11-12 Atefeh Sohrabizadeh , Yuze Chi , Jason Cong

Leveraging knowledge from electronic health records (EHRs) to predict a patient's condition is essential to the effective delivery of appropriate care. Clinical notes of patient EHRs contain valuable information from healthcare…

计算与语言 · 计算机科学 2023-05-18 Nayeon Kim , Yinhua Piao , Sun Kim

With the arrival of the big data era, more and more data are becoming readily available in various real-world applications and those data are usually highly heterogeneous. Taking computational medicine as an example, we have both Electronic…

机器学习 · 计算机科学 2019-05-08 Xi Sheryl Zhang , Jingyuan Chou , Fei Wang

Cardiovascular diseases are a leading cause of death and disability worldwide. Electrocardiogram (ECG) is critical for diagnosing and monitoring cardiac health, but obtaining large-scale annotated ECG datasets is labor-intensive and…

信号处理 · 电气工程与系统科学 2025-09-22 Mingsheng Cai , Jiuming Jiang , Wenhao Huang , Che Liu , Rossella Arcucci

Link prediction is a key aspect of graph machine learning, with applications as diverse as disease prediction, social network recommendations, and drug discovery. It involves predicting new links that may form between network nodes. Despite…

机器学习 · 计算机科学 2023-09-12 Haohui Lu , Shahadat Uddin

Heterogeneous graph neural networks (HGNNs) have powerful capability to embed rich structural and semantic information of a heterogeneous graph into node representations. Existing HGNNs inherit many mechanisms from graph neural networks…

机器学习 · 计算机科学 2023-09-04 Xiaocheng Yang , Mingyu Yan , Shirui Pan , Xiaochun Ye , Dongrui Fan

Heterogeneity is a fundamental characteristic of cancer. To accommodate heterogeneity, subgroup identification has been extensively studied and broadly categorized into unsupervised and supervised analysis. Compared to unsupervised…

统计方法学 · 统计学 2026-02-25 Xing Qin , Xu Liu , Shuangge Ma , Mengyun Wu

Heterogeneous graph neural network (HGNN) is a very popular technique for the modeling and analysis of heterogeneous graphs. Most existing HGNN-based approaches are supervised or semi-supervised learning methods requiring graphs to be…

机器学习 · 计算机科学 2023-11-17 Cuiying Huo , Dongxiao He , Yawen Li , Di Jin , Jianwu Dang , Weixiong Zhang , Witold Pedrycz , Lingfei Wu

Real-world graph data environments intrinsically exist noise (e.g., link and structure errors) that inevitably disturb the effectiveness of graph representation and downstream learning tasks. For homogeneous graphs, the latest works use…

机器学习 · 计算机科学 2024-12-25 Xiong Zhang , Cheng Xie , Haoran Duan , Beibei Yu

Cardiovascular disease (CVD) remains the foremost cause of mortality worldwide, underscoring the urgent need for intelligent and data-driven diagnostic tools. Traditional predictive models often struggle to generalize across heterogeneous…

人工智能 · 计算机科学 2026-01-27 Rajan Das Gupta , Xiaobin Wu , Xun Liu , Jiaqi He

Accurate multi-label classification of electrocardiogram (ECG) signals remains challenging due to the coexistence of multiple cardiac conditions, pronounced class imbalance, and long-range temporal dependencies in multi-lead recordings.…

机器学习 · 计算机科学 2026-01-28 Alireza Jafari , Fatemeh Jafari

Prediction the conversion to early-stage dementia is critical for mitigating its progression but remains challenging due to subtle cognitive impairments and structural brain changes. Traditional T1-weighted magnetic resonance imaging…

计算机视觉与模式识别 · 计算机科学 2024-06-28 Yilin Leng , Wenju Cui , Bai Chen , Xi Jiang , Shuangqing Chen , Jian Zheng

Graph similarity learning refers to calculating the similarity score between two graphs, which is required in many realistic applications, such as visual tracking, graph classification, and collaborative filtering. As most of the existing…

机器学习 · 计算机科学 2022-07-13 Di Jin , Luzhi Wang , Yizhen Zheng , Xiang Li , Fei Jiang , Wei Lin , Shirui Pan

Predicting patient mortality is an important and challenging problem in the healthcare domain, especially for intensive care unit (ICU) patients. Electronic health notes serve as a rich source for learning patient representations, that can…

计算与语言 · 计算机科学 2019-10-16 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu , Yuan Luo

We present a machine learning pipeline and model that uses the entire uncurated EHR for prediction of in-hospital mortality at arbitrary time intervals, using all available chart, lab and output events, without the need for pre-processing…

机器学习 · 计算机科学 2019-09-18 Jacob Deasy , Pietro Liò , Ari Ercole

In this paper, we present XST-GCNN (eXplainable Spatio-Temporal Graph Convolutional Neural Network), a novel architecture for processing heterogeneous and irregular Multivariate Time Series (MTS) data. Our approach captures temporal and…

机器学习 · 计算机科学 2024-11-05 Óscar Escudero-Arnanz , Cristina Soguero-Ruiz , Antonio G. Marques

Learning a similarity metric has gained much attention recently, where the goal is to learn a function that maps input patterns to a target space while preserving the semantic distance in the input space. While most related work focused on…

计算机视觉与模式识别 · 计算机科学 2019-05-03 Guixiang Ma , Nesreen K. Ahmed , Ted Willke , Dipanjan Sengupta , Michael W. Cole , Nicholas B. Turk-Browne , Philip S. Yu

Score-based graph generative models (SGGMs) have proven effective in critical applications such as drug discovery and protein synthesis. However, their theoretical behavior, particularly regarding convergence, remains underexplored. Unlike…

机器学习 · 计算机科学 2025-08-21 Junwei Su , Chuan Wu

Graph neural networks (GNNs) have been developed to model the relationship between regions of interest (ROIs) in brains and have shown significant improvement in detecting brain diseases. However, most of these frameworks do not consider…

机器学习 · 计算机科学 2025-06-23 Falih Gozi Febrinanto , Adonia Simango , Chengpei Xu , Jingjing Zhou , Jiangang Ma , Sonika Tyagi , Feng Xia