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Cohort studies of the onset of a disease often encounter left-truncation on the event time of interest in addition to right-censoring due to variable enrollment times of study participants. Analysis of such event time data can be biased if…

统计方法学 · 统计学 2025-04-11 Spencer Matthews , Bin Nan

Time-to-event outcomes are commonly used as primary endpoints in randomized clinical trials. Despite this, relatively little work incorporates baseline covariate information while also accounting for stratified randomization, a common form…

统计方法学 · 统计学 2026-05-01 Raphael C. Kim , Brian Gilbert , Ramin Zabih , Michele Santacatterina , Ivan Diaz

This paper provides guidance for researchers with some mathematical background on the conduct of time-to-event analysis in observational studies based on intensity (hazard) models. Discussions of basic concepts like time axis, event…

Convergence results for averages of independent replications of counting processes are established in a $p$-variation setting and under certain assumptions. Such convergence results can be combined with functional differentiability results…

概率论 · 数学 2019-03-12 Morten Overgaard

Massive sized survival datasets are becoming increasingly prevalent with the development of the healthcare industry. Such datasets pose computational challenges unprecedented in traditional survival analysis use-cases. A popular way for…

统计方法学 · 统计学 2023-05-09 Nir Keret , Malka Gorfine

We aim to develop a tool for understanding how the mental health of youth aged less than 18 years evolve over time through administrative records of mental health related emergency department (MHED) visits in two decades. Administrative…

统计方法学 · 统计学 2024-07-16 Yi Xiong , Joan Hu , Rhonda Rosychuk

The life course perspective in criminology has become prominent last years, offering valuable insights into various patterns of criminal offending and pathways. The study of criminal trajectories aims to understand the beginning,…

统计方法学 · 统计学 2024-08-30 Alisson C. C. Silva , Fábio N. Demarqui , Bráulio F. Silva , Marcos O. Prates

Although increasingly used as a data resource for assembling cohorts, electronic health records (EHRs) pose many analytic challenges. In particular, a patient's health status influences when and what data are recorded, generating sampling…

统计方法学 · 统计学 2020-04-28 Yifei Sun , Charles E. McCulloch , Kieren A. Marr , Chiung-Yu Huang

Digital monitoring studies collect real-time high frequency data via mobile sensors in the subjects' natural environment. This data can be used to model the impact of changes in physiology on recurrent event outcomes such as smoking, drug…

统计方法学 · 统计学 2022-04-15 Walter Dempsey

Event of the same type occurring several times for one individual (recurrent events) are present in various domains (industrial systems reliability, episodes of unemployment, political conflicts, chronic diseases episodes). Analysis of such…

应用统计 · 统计学 2024-01-24 Génia Babykina , Vincent Vandewalle

We propose a novel approach to estimate the Cox model with temporal covariates. Our new approach treats the temporal covariates as arising from a longitudinal process which is modeled jointly with the event time. Different from the…

统计方法学 · 统计学 2018-02-05 Xiaoqi Zhang , Xiaobing Zhao , Yanqiao Zheng

Leveraging external or historical data to improve the efficiency of randomized clinical trials without introducing bias or inflating the Type I error rate remains challenging. Recent work on externally trained prognostic scores, such as…

统计方法学 · 统计学 2026-05-28 Junyi Zhou , Qing Liu , May Mo , Amy Xia

The conditional survival function of a time-to-event outcome subject to censoring and truncation is a common target of estimation in survival analysis. This parameter may be of scientific interest and also often appears as a nuisance in…

统计方法学 · 统计学 2024-08-20 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

This paper presents a stochastic model predictive controller (SMPC) for linear time-invariant systems in the presence of additive disturbances. The distribution of the disturbance is unknown and is assumed to have a bounded support. A…

系统与控制 · 电气工程与系统科学 2022-10-03 Hotae Lee , Monimoy Bujarbaruah , Francesco Borrelli

We present new estimators for the statistical analysis of the dependence of the mean gap time length between consecutive recurrent events, on a set of explanatory random variables and in the presence of right censoring. The dependence is…

应用统计 · 统计学 2021-09-10 Ioana Schiopu-Kratina , Hai Yan Liu , Mayer Alvo , Pierre-Jerome Bergeron

Time-to-event endpoints are frequently used as outcomes in oncology and other disease areas where the outcome of interest may not be observed within a predetermined period. Although many analytical methods address the challenges of…

统计方法学 · 统计学 2026-04-14 Chen-Yen Lin , Susan Halabi , Taehwa Choi

Interval-censored data arise frequently in scientific studies, where the event of interest is known only to occur within a specific time interval. In such studies, functional covariates taking the form of continuous curves or spatial…

统计方法学 · 统计学 2026-05-18 Yangjianchen Xu , Peijun Sang

Medical studies that depend on electronic health records (EHR) data are often subject to measurement error, as the data are not collected to support research questions under study. These data errors, if not accounted for in study analyses,…

统计方法学 · 统计学 2020-03-10 Eric J. Oh , Bryan E. Shepherd , Thomas Lumley , Pamela A. Shaw

Time-to-event models are a popular tool to analyse data where the outcome variable is the time to the occurrence of a specific event of interest. Here we focus on the analysis of time-to-event outcomes that are either intrisically discrete…

应用统计 · 统计学 2017-04-14 Moritz Berger , Matthias Schmid

Diverse analysis approaches have been proposed to distinguish data missing due to death from nonresponse, and to summarize trajectories of longitudinal data truncated by death. We demonstrate how these analysis approaches arise from…

统计方法学 · 统计学 2010-01-18 Brenda F. Kurland , Laura L. Johnson , Brian L. Egleston , Paula H. Diehr