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Propensity scores are commonly used to reduce the confounding bias in non-randomized observational studies for estimating the average treatment effect. An important assumption underlying this approach is that all confounders that are…

统计方法学 · 统计学 2022-08-02 Youfei Yu , Jiacong Du , Min Zhang , Zhenke Wu , Andrew M. Ryan , Bhramar Mukherjee

The development of molecular diagnostic tools to achieve individualized medicine requires identifying predictive biomarkers associated with subgroups of individuals who might receive beneficial or harmful effects from different available…

统计方法学 · 统计学 2020-01-20 Shonosuke Sugasawa , Hisashi Noma

Current methods for detecting spurious correlations rely on analyzing dataset statistics or error patterns, leaving many harmful shortcuts invisible when counterexamples are absent. We introduce BEE (Bridging Explainability and Embeddings),…

Treatment specific survival curves are an important tool to illustrate the treatment effect in studies with time-to-event outcomes. In non-randomized studies, unadjusted estimates can lead to biased depictions due to confounding. Multiple…

统计方法学 · 统计学 2023-04-25 Robin Denz , Renate Klaaßen-Mielke , Nina Timmesfeld

The family-wise error rate (FWER) has been widely used in genome-wide association studies. With the increasing availability of functional genomics data, it is possible to increase the detection power by leveraging these genomic functional…

统计方法学 · 统计学 2020-12-25 Huijuan Zhou , Xianyang Zhang , Jun Chen

In the high dimensional regression analysis when the number of predictors is much larger than the sample size, an important question is to select the important variable which are relevant to the response variable of interest. Variable…

统计方法学 · 统计学 2023-01-09 Pengsheng Ji , Zhigen Zhao

The knockoff-based multiple testing setup of Barber & Candes (2015) for variable selection in multiple regression where sample size is as large as the number of explanatory variables is considered. The method of Benjamini & Hochberg (1995)…

统计方法学 · 统计学 2021-08-20 Sanat K. Sarkar , Cheng Yong Tang

Frequentist statistical methods, such as hypothesis testing, are standard practice in papers that provide benchmark comparisons. Unfortunately, these methods have often been misused, e.g., without testing for their statistical test…

统计方法学 · 统计学 2021-05-18 David Issa Mattos , Jan Bosch , Helena Holmström Olsson

Matching is a widely used causal inference design that aims to approximate a randomized experiment using observational data by forming matched sets of treated and control units based on similarities in their covariates. Ideally, treated…

统计方法学 · 统计学 2026-04-06 Jianan Zhu , Jeffrey Zhang , Zijian Guo , Siyu Heng

We study a large-scale one-sided multiple testing problem in which test statistics follow normal distributions with unit variance, and the goal is to identify signals with positive mean effects. A conventional approach is to compute…

统计方法学 · 统计学 2026-05-15 Kwangok Seo , Johan Lim , Hyungwon Choi , Jaesik Jeong

Automatic metrics are now central to evaluating text-to-image models, often substituting for human judgment in benchmarking and large-scale filtering. However, it remains unclear whether these metrics truly prioritize semantic correctness…

计算机视觉与模式识别 · 计算机科学 2026-01-13 Subhadeep Roy , Gagan Bhatia , Steffen Eger

The most popular multiple testing procedures are stepwise procedures based on $P$-values for individual test statistics. Included among these are the false discovery rate (FDR) controlling procedures of Benjamini--Hochberg [J. Roy. Statist.…

统计理论 · 数学 2009-06-18 Arthur Cohen , Harold B. Sackrowitz , Minya Xu

Valid statistical inference is challenging when the sample is subject to unknown selection bias. Data integration can be used to correct for selection bias when we have a parallel probability sample from the same population with some common…

统计方法学 · 统计学 2023-07-24 Zhonglei Wang , Shu Yang , Jae Kwang Kim

Propensity score methods are an important tool to help reduce confounding in non-experimental studies. Most propensity score methods assume that covariates are measured without error. However, covariates are often measured with error, which…

统计方法学 · 统计学 2017-06-08 Hwanhee Hong , David A. Aaby , Juned Siddique , Elizabeth A. Stuart

Ultra high-throughput sequencing of transcriptomes (RNA-Seq) has enabled the accurate estimation of gene expression at individual isoform level. However, systematic biases introduced during the sequencing and mapping processes as well as…

统计方法学 · 统计学 2013-10-02 Hui Jiang , Julia Salzman

A new approach for Bayesian model averaging (BMA) and selection is proposed, based on the mixture model approach for hypothesis testing in Kaniav et al., 2014. Inheriting from the good properties of this approach, it extends BMA to cases…

统计方法学 · 统计学 2018-08-02 Merlin Keller , Kaniav Kamary

Abstract Publication bias has been a problem facing meta-analysts. Methods adjusting for publication bias have been proposed in the literature. Comparative studies for methods adjusting for publication bias are found in the literature, but…

应用统计 · 统计学 2024-10-10 Osama Almalik

Many biological assays are employed in virology to quantify parameters of interest. Two such classes of assays, virus quantification assays (VQA) and infectivity assays (IA), aim to estimate the number of viruses present in a solution, and…

定量方法 · 定量生物学 2018-08-01 Bhaven Mistry , Maria R. D'Orsogna , Tom Chou

Considerable interest has recently been focused on studying multiple phenotypes simultaneously in both epidemiological and genomic studies, either to capture the multidimensionality of complex disorders or to understand shared etiology of…

统计方法学 · 统计学 2015-11-26 Denis Agniel , Katherine P. Liao , Tianxi Cai

AB testing aids business operators with their decision making, and is considered the gold standard method for learning from data to improve digital user experiences. However, there is usually a gap between the requirements of practitioners,…