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Modern single-cell flow and mass cytometry technologies measure the expression of several proteins of the individual cells within a blood or tissue sample. Each profiled biological sample is thus represented by a set of hundreds of…

机器学习 · 计算机科学 2022-06-29 Siyuan Shan , Vishal Baskaran , Haidong Yi , Jolene Ranek , Natalie Stanley , Junier Oliva

Convolutional Neural Networks (CNN) have recently seen tremendous success in various computer vision tasks. However, their application to problems with high dimensional input and output, such as high-resolution image and video segmentation…

计算机视觉与模式识别 · 计算机科学 2020-07-09 Keegan Lensink , Bas Peters , Eldad Haber

Electronic Health Records have become popular sources of data for secondary research, but their use is hampered by the amount of effort it takes to overcome the sparsity, irregularity, and noise that they contain. Modern learning…

应用统计 · 统计学 2025-02-28 Jacek M. Bajor , Diego A. Mesa , Travis J. Osterman , Thomas A. Lasko

Most real-world datasets consist of a natural hierarchy between classes or an inherent label structure that is either already available or can be constructed cheaply. However, most existing representation learning methods ignore this…

机器学习 · 计算机科学 2024-12-03 Aditya Sinha , Siqi Zeng , Makoto Yamada , Han Zhao

Deploying accurate event detection on resource-constrained devices is challenged by the trade-off between performance and computational cost. While Early-Exit (EE) networks offer a solution through adaptive computation, they often fail to…

Knowledge graphs have emerged as fundamental structures for representing complex relational data across scientific and enterprise domains. However, existing embedding methods face critical limitations when modeling diverse relationship…

人工智能 · 计算机科学 2025-11-17 Jugal Gajjar , Kaustik Ranaware , Kamalasankari Subramaniakuppusamy , Vaibhav Gandhi

Neuro-encoded expression programming(NEEP) that aims to offer a novel continuous representation of combinatorial encoding for genetic programming methods is proposed in this paper. Genetic programming with linear representation uses…

神经与进化计算 · 计算机科学 2021-04-12 Aftab Anjum , Fengyang Sun , Lin Wang , Jeff Orchard

Learning the representation of data with hierarchical structures in the hyperbolic space attracts increasing attention in recent years. Due to the constant negative curvature, the hyperbolic space resembles tree metrics and captures the…

机器学习 · 计算机科学 2022-02-21 Huiru Xiao , Caigao Jiang , Yangqiu Song , James Zhang , Junwu Xiong

The immense increase in the generation of genomic scale data poses an unmet analytical challenge, due to a lack of established methodology with the required flexibility and power. We propose a first principled approach to statistical…

Diffusion generative models (DMs) have achieved promising results in image and graph generation. However, real-world graphs, such as social networks, molecular graphs, and traffic graphs, generally share non-Euclidean topologies and hidden…

机器学习 · 计算机科学 2024-01-04 Lingfeng Wen , Xuan Tang , Mingjie Ouyang , Xiangxiang Shen , Jian Yang , Daxin Zhu , Mingsong Chen , Xian Wei

Obtaining continuous representations of structural data such as directed acyclic graphs (DAGs) has gained attention in machine learning and artificial intelligence. However, embedding complex DAGs in which both ancestors and descendants of…

机器学习 · 计算机科学 2019-05-16 Ryota Suzuki , Ryusuke Takahama , Shun Onoda

Human motion taxonomies serve as high-level hierarchical abstractions that classify how humans move and interact with their environment. They have proven useful to analyse grasps, manipulation skills, and whole-body support poses. Despite…

机器人学 · 计算机科学 2024-09-17 Noémie Jaquier , Leonel Rozo , Miguel González-Duque , Viacheslav Borovitskiy , Tamim Asfour

Since the completion of the human genome sequencing project in 2001, significant progress has been made in areas such as gene regulation editing and protein structure prediction. However, given the vast amount of genomic data, the segments…

其他定量生物学 · 定量生物学 2025-01-29 Wang Liang

In semi-supervised learning, methods that rely on confidence learning to generate pseudo-labels have been widely proposed. However, increasing research finds that when faced with noisy and biased data, the model's representation network is…

计算机视觉与模式识别 · 计算机科学 2024-04-29 Yanbiao Ma , Licheng Jiao , Fang Liu , Lingling Li , Shuyuan Yang , Xu Liu

Recent research in representation learning has shown that hierarchical data lends itself to low-dimensional and highly informative representations in hyperbolic space. However, even if hyperbolic embeddings have gathered attention in image…

计算机视觉与模式识别 · 计算机科学 2023-09-20 Gabriel Moreira , Manuel Marques , João Paulo Costeira , Alexander Hauptmann

Representation learning over temporal networks has drawn considerable attention in recent years. Efforts are mainly focused on modeling structural dependencies and temporal evolving regularities in Euclidean space which, however,…

社会与信息网络 · 计算机科学 2023-01-31 Menglin Yang , Min Zhou , Marcus Kalander , Zengfeng Huang , Irwin King

Precision oncology requires accurate molecular insights, yet obtaining these directly from genomics is costly and time-consuming for broad clinical use. Predicting complex molecular features and patient prognosis directly from routine…

计算机视觉与模式识别 · 计算机科学 2025-06-25 Cheng Jin , Fengtao Zhou , Yunfang Yu , Jiabo Ma , Yihui Wang , Yingxue Xu , Huajun Zhou , Hao Jiang , Luyang Luo , Luhui Mao , Zifan He , Xiuming Zhang , Jing Zhang , Ronald Chan , Herui Yao , Hao Chen

Proteins perform much of the work in living organisms, and consequently the development of efficient computational methods for protein representation is essential for advancing large-scale biological research. Most current approaches…

定量方法 · 定量生物学 2023-06-09 Francesco Ceccarelli , Lorenzo Giusti , Sean B. Holden , Pietro Liò

Hyperbolic neural networks have emerged as a powerful tool for modeling hierarchical data structures prevalent in real-world datasets. Notably, residual connections, which facilitate the direct flow of information across layers, have been…

机器学习 · 计算机科学 2025-01-14 Neil He , Menglin Yang , Rex Ying

Representation learning has become an invaluable approach for learning from symbolic data such as text and graphs. However, while complex symbolic datasets often exhibit a latent hierarchical structure, state-of-the-art methods typically…

人工智能 · 计算机科学 2017-05-29 Maximilian Nickel , Douwe Kiela