中文
相关论文

相关论文: Hyperbolic Genome Embeddings

200 篇论文

Sequence modelling approaches for epigenetic profile prediction have recently expanded in terms of sequence length, model size, and profile diversity. However, current models cannot infer on many experimentally feasible tissue and assay…

基因组学 · 定量生物学 2023-08-24 Jacob Deasy , Ron Schwessinger , Ferran Gonzalez , Stephen Young , Kim Branson

Learning hyperbolic embeddings for knowledge graph (KG) has gained increasing attention due to its superiority in capturing hierarchies. However, some important operations in hyperbolic space still lack good definitions, making existing…

机器学习 · 计算机科学 2023-02-09 Wentao Shi , Junkang Wu , Xuezhi Cao , Jiawei Chen , Wenqiang Lei , Wei Wu , Xiangnan He

Recently, Graph Convolution Network (GCN) based methods have achieved outstanding performance for recommendation. These methods embed users and items in Euclidean space, and perform graph convolution on user-item interaction graphs.…

信息检索 · 计算机科学 2021-08-11 Liping Wang , Fenyu Hu , Shu Wu , Liang Wang

Learning embeddings of entities and relations existing in knowledge bases allows the discovery of hidden patterns in data. In this work, we examine the geometrical space's contribution to the task of knowledge base completion. We focus on…

计算与语言 · 计算机科学 2019-08-20 Prodromos Kolyvakis , Alexandros Kalousis , Dimitris Kiritsis

Hyperbolic spaces, which have the capacity to embed tree structures without distortion owing to their exponential volume growth, have recently been applied to machine learning to better capture the hierarchical nature of data. In this…

机器学习 · 计算机科学 2021-03-18 Ryohei Shimizu , Yusuke Mukuta , Tatsuya Harada

Knowledge hypergraphs generalize knowledge graphs using hyperedges to connect multiple entities and depict complicated relations. Existing methods either transform hyperedges into an easier-to-handle set of binary relations or view…

机器学习 · 计算机科学 2024-12-18 Mengfan Li , Xuanhua Shi , Chenqi Qiao , Teng Zhang , Hai Jin

Embedded topic models are able to learn interpretable topics even with large and heavy-tailed vocabularies. However, they generally hold the Euclidean embedding space assumption, leading to a basic limitation in capturing hierarchical…

信息检索 · 计算机科学 2022-10-20 Yishi Xu , Dongsheng Wang , Bo Chen , Ruiying Lu , Zhibin Duan , Mingyuan Zhou

In genome-scale constraint-based metabolic models, gene deletion strategies are essential for achieving growth-coupled production, where cell growth and target metabolite synthesis occur simultaneously. Despite the inherently networked…

定量方法 · 定量生物学 2026-04-10 Ziwei Yang , Takeyuki Tamura

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

基因组学 · 定量生物学 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

Hyperbolic representation learning has been widely used to extract implicit hierarchies within data, and recently it has found its way to the open-world classification task of Generalized Category Discovery (GCD). However, prior hyperbolic…

机器学习 · 计算机科学 2026-02-06 Mohamad Dalal , Thomas B. Moeslund , Joakim Bruslund Haurum

In practice, many medical datasets have an underlying taxonomy defined over the disease label space. However, existing classification algorithms for medical diagnoses often assume semantically independent labels. In this study, we aim to…

计算机视觉与模式识别 · 计算机科学 2022-09-14 Zhen Yu , Toan Nguyen , Yaniv Gal , Lie Ju , Shekhar S. Chandra , Lei Zhang , Paul Bonnington , Victoria Mar , Zhiyong Wang , Zongyuan Ge

The application of deep learning methods, particularly foundation models, in biological research has surged in recent years. These models can be text-based or trained on underlying biological data, especially omics data of various types.…

人工智能 · 计算机科学 2024-12-06 Yoav Kan-Tor , Michael Morris Danziger , Eden Zohar , Matan Ninio , Yishai Shimoni

Due to its geometric properties, hyperbolic space can support high-fidelity embeddings of tree- and graph-structured data, upon which various hyperbolic networks have been developed. Existing hyperbolic networks encode geometric priors not…

机器学习 · 计算机科学 2023-03-14 Tao Yu , Christopher De Sa

Natural language text exhibits hierarchical structure in a variety of respects. Ideally, we could incorporate our prior knowledge of this hierarchical structure into unsupervised learning algorithms that work on text data. Recent work by…

计算与语言 · 计算机科学 2018-06-13 Bhuwan Dhingra , Christopher J. Shallue , Mohammad Norouzi , Andrew M. Dai , George E. Dahl

We introduce hyperbolic attention networks to endow neural networks with enough capacity to match the complexity of data with hierarchical and power-law structure. A few recent approaches have successfully demonstrated the benefits of…

Electroencephalography (EEG)-based brain-computer interfaces facilitate direct communication with a computer, enabling promising applications in human-computer interactions. However, their utility is currently limited because EEG decoding…

机器学习 · 计算机科学 2026-02-10 Shanglin Li , Shiwen Chu , Okan Koç , Yi Ding , Qibin Zhao , Motoaki Kawanabe , Ziheng Chen

Recently, there has been a rising surge of momentum for deep representation learning in hyperbolic spaces due to theirhigh capacity of modeling data like knowledge graphs or synonym hierarchies, possessing hierarchical structure. We refer…

机器学习 · 计算机科学 2021-02-18 Wei Peng , Tuomas Varanka , Abdelrahman Mostafa , Henglin Shi , Guoying Zhao

Foundation models pre-trained on massive datasets, including large language models (LLMs), vision-language models (VLMs), and large multimodal models, have demonstrated remarkable success in diverse downstream tasks. However, recent studies…

机器学习 · 计算机科学 2025-07-25 Neil He , Hiren Madhu , Ngoc Bui , Menglin Yang , Rex Ying

Large language models (LLMs) have achieved remarkable success and demonstrated superior performance across various tasks, including natural language processing (NLP), weather forecasting, biological protein folding, text generation, and…

人工智能 · 计算机科学 2025-12-09 Sarang Patil , Zeyong Zhang , Yiran Huang , Tengfei Ma , Mengjia Xu

Gene expression datasets offer insights into gene regulation mechanisms, biochemical pathways, and cellular functions. Additionally, comparing gene expression profiles between disease and control patients can deepen the understanding of…

机器学习 · 计算机科学 2025-03-27 Rita T. Sousa , Heiko Paulheim