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Invertible flow-based generative models are an effective method for learning to generate samples, while allowing for tractable likelihood computation and inference. However, the invertibility requirement restricts models to have the same…

机器学习 · 计算机科学 2020-02-21 Abhishek Kumar , Ben Poole , Kevin Murphy

Stepped-wedge cluster randomized trials (SW-CRTs) evaluate interventions rolled out across clusters over time. Standard analyses typically use immediate-treatment (IT) models, which assume effects begin at crossover and remain constant…

统计方法学 · 统计学 2026-04-21 Yongdong Ouyang , Monica Taljaard , James P. Hughes , Fan Li

High-dimensional longitudinal data have become increasingly prevalent in recent studies, and penalized generalized estimating equations (GEEs) are often used to model such data. However, the desirable properties of the GEE method can break…

统计方法学 · 统计学 2025-01-03 Yue Ma , Haofeng Wang , Xuejun Jiang

We study system design problems stated as parameterized stochastic programs with a chance-constraint set. We adopt a Bayesian approach that requires the computation of a posterior predictive integral which is usually intractable. In…

机器学习 · 统计学 2020-01-07 Prateek Jaiswal , Harsha Honnappa , Vinayak A. Rao

In cancer research, profiling studies have been extensively conducted, searching for genes/SNPs associated with prognosis. Cancer is a heterogeneous disease. Examining similarity and difference in the genetic basis of multiple subtypes of…

统计方法学 · 统计学 2013-04-18 Jin Liu , Jian Huang , Yawei Zhang , Qing Lan , Nathaniel Rothman , Tongzhang Zheng , Shuangge Ma

Clustered Federated Multitask Learning (CFL) was introduced as an efficient scheme to obtain reliable specialized models when data is imbalanced and distributed in a non-i.i.d. (non-independent and identically distributed) fashion amongst…

分布式、并行与集群计算 · 计算机科学 2021-08-20 Abdullatif Albaseer , Mohamed Abdallah , Ala Al-Fuqaha , Aiman Erbad

Stratification in both the design and analysis of randomized clinical trials is common. Despite features in automated randomization systems to re-confirm the stratifying variables, incorrect values of these variables may be entered. These…

统计方法学 · 统计学 2023-07-24 Neal Thomas

Federated Learning (FL) typically aggregates client model parameters using a weighting approach determined by sample proportions. However, this naive weighting method may lead to unfairness and degradation in model performance due to…

机器学习 · 计算机科学 2023-11-13 Mingwei Xu , Xiaofeng Cao , Ivor W. Tsang , James T. Kwok

In Randomised Controlled Trials (RCT) with treatment non-compliance, instrumental variable approaches are used to estimate complier average causal effects. We extend these approaches to cost-effectiveness analyses, where methods need to…

统计方法学 · 统计学 2016-12-02 Karla DiazOrdaz , Angelo Franchini , Richard Grieve

Generalized estimating equations (GEE) are of great importance in analyzing clustered data without full specification of multivariate distributions. A recent approach jointly models the mean, variance, and correlation coefficients of…

统计方法学 · 统计学 2025-01-13 Zhenyu Xu , Jason P. Fine , Wenling Song , Jun Yan

The statistical efficiency of randomized clinical trials can be improved by incorporating information from baseline covariates (i.e., pre-treatment patient characteristics). This can be done in the design stage using stratified (permutated…

统计方法学 · 统计学 2025-02-04 Zhiwei Zhang

The diversity in disease profiles and therapeutic approaches between hospitals and health professionals underscores the need for patient-centric personalized strategies in healthcare. Alongside this, similarities in disease progression…

机器学习 · 计算机科学 2025-05-23 Navid Seidi , Satyaki Roy , Sajal K. Das , Ardhendu Tripathy

Statistical learning with a large number of rare binary features is commonly encountered in analyzing electronic health records (EHR) data, especially in the modeling of disease onset with prior medical diagnoses and procedures. Dealing…

机器学习 · 计算机科学 2024-02-28 Jianmin Chen , Robert H. Aseltine , Fei Wang , Kun Chen

Stability selection is a versatile framework for structure estimation and variable selection in high-dimensional setting, primarily grounded in frequentist principles. In this paper, we propose an enhanced methodology that integrates…

统计方法学 · 统计学 2026-05-05 Mahdi Nouraie , Connor Smith , Samuel Muller

In this work we provide a simple estimation procedure for a general frailty model for analysis of prospective correlated failure times. Rigorous large-sample theory for the proposed estimators of both the regression coefficient vector and…

统计理论 · 数学 2007-06-13 Malka Gorfine , David M. Zucker , Li Hsu

The stochastic approximation EM algorithm (SAEM) is described for the estimation of item and person parameters given test data coded as dichotomous or ordinal variables. The method hinges upon the eigenanalysis of missing variables sampled…

统计方法学 · 统计学 2020-01-01 Eugene Geis

Generative models excel at synthesizing high-fidelity samples from complex data distributions, but they often violate hard constraints arising from physical laws or task specifications. A common remedy is to project intermediate samples…

机器学习 · 计算机科学 2025-09-30 Jinhao Liang , Yixuan Sun , Anirban Samaddar , Sandeep Madireddy , Ferdinando Fioretto

We consider continuous-time sparse stochastic processes from which we have only a finite number of noisy/noiseless samples. Our goal is to estimate the noiseless samples (denoising) and the signal in-between (interpolation problem). By…

机器学习 · 计算机科学 2015-06-11 Arash Amini , Ulugbek S. Kamilov , Emrah Bostan , Michael Unser

This paper compares six different parameter estimation methods for shared frailty models via a series of simulation studies. A shared frailty model is a survival model that incorporates a random effect term, where the frailties are common…

统计方法学 · 统计学 2023-11-21 Tingxuan Wu , Cindy Feng , Longhai Li

We provide in this paper a fully adaptive penalized procedure to select a covariance among a collection of models observing i.i.d replications of the process at fixed observation points. For this we generalize previous results of Bigot and…

统计理论 · 数学 2012-03-05 Rolando Biscay , Hélène Lescornel , Jean-Michel Loubes