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Background: Automatic extraction of chemical-disease relations (CDR) from unstructured text is of essential importance for disease treatment and drug development. Meanwhile, biomedical experts have built many highly-structured knowledge…

计算与语言 · 计算机科学 2019-12-24 Huiwei Zhou , Chengkun Lang , Zhuang Liu , Shixian Ning , Yingyu Lin , Lei Du

Fine-tuning pre-trained language models (PLMs) has recently shown a potential to improve knowledge graph completion (KGC). However, most PLM-based methods focus solely on encoding textual information, neglecting the long-tailed nature of…

计算与语言 · 计算机科学 2025-02-03 Youmin Ko , Hyemin Yang , Taeuk Kim , Hyunjoon Kim

The automatic construction of knowledge graphs (KGs) is an important research area in medicine, with far-reaching applications spanning drug discovery and clinical trial design. These applications hinge on the accurate identification of…

计算与语言 · 计算机科学 2025-01-30 Vahan Arsenyan , Spartak Bughdaryan , Fadi Shaya , Kent Small , Davit Shahnazaryan

Retrieval-Augmented Generation (RAG) mitigates hallucinations in Large Language Models (LLMs) by integrating external knowledge. However, conflicts between parametric knowledge and retrieved context pose challenges, particularly when…

计算与语言 · 计算机科学 2025-03-21 Baolong Bi , Shenghua Liu , Yiwei Wang , Yilong Xu , Junfeng Fang , Lingrui Mei , Xueqi Cheng

Knowledge Graph Completion (KGC) has been proposed to improve Knowledge Graphs by filling in missing connections via link prediction or relation extraction. One of the main difficulties for KGC is a low resource problem. Previous approaches…

计算与语言 · 计算机科学 2023-01-26 Ningyu Zhang , Shumin Deng , Zhanlin Sun , Jiaoayan Chen , Wei Zhang , Huajun Chen

Recently, prompt-tuning has achieved promising results for specific few-shot classification tasks. The core idea of prompt-tuning is to insert text pieces (i.e., templates) into the input and transform a classification task into a masked…

计算与语言 · 计算机科学 2023-09-19 Xiang Chen , Ningyu Zhang , Xin Xie , Shumin Deng , Yunzhi Yao , Chuanqi Tan , Fei Huang , Luo Si , Huajun Chen

In many academic settings, medical students start their scientific work already during their studies. Like at our institution, they often work in interdisciplinary teams with more or less experienced (postgraduate) researchers of…

机器学习 · 统计学 2020-12-08 Andreas D. Meid

This paper aims to enhance the few-shot relation classification especially for sentences that jointly describe multiple relations. Due to the fact that some relations usually keep high co-occurrence in the same context, previous few-shot…

计算与语言 · 计算机科学 2020-10-22 Yingyao Wang , Junwei Bao , Guangyi Liu , Youzheng Wu , Xiaodong He , Bowen Zhou , Tiejun Zhao

Clinical text classification requires choosing between specialized fine-tuned models (BERT variants) and general-purpose large language models (LLMs), yet neither dominates across all instances. We introduce Learning to Defer for clinical…

计算与语言 · 计算机科学 2026-04-16 Rishik Kondadadi , John E. Ortega

In Natural Language Processing (NLP), Machine Reading Comprehension (MRC) is the task of answering a question based on a given context. To handle questions in the medical domain, modern language models such as BioBERT, SciBERT and even…

计算与语言 · 计算机科学 2024-12-16 Saptarshi Sengupta , Connor Heaton , Suhan Cui , Soumalya Sarkar , Prasenjit Mitra

Knowledge Tracing (KT) is a critical technique for modeling student knowledge to support personalized learning. However, most KT systems focus on binary correctness prediction and cannot diagnose the underlying conceptual misunderstandings…

计算与语言 · 计算机科学 2026-03-26 Yu-Chen Kang , Yu-Chien Tang , An-Zi Yen

Continually solving new, unsolved tasks is the key to learning diverse behaviors. Through reinforcement learning (RL), we have made massive strides towards solving tasks that have a single goal. However, in the multi-task domain, where an…

机器学习 · 计算机科学 2020-06-18 Yunzhi Zhang , Pieter Abbeel , Lerrel Pinto

In clinical treatment, identifying potential adverse reactions of drugs can help assist doctors in making medication decisions. In response to the problems in previous studies that features are high-dimensional and sparse, independent…

定量方法 · 定量生物学 2024-07-30 Yufeng Li , Wenchao Zhao , Bo Dang , Xu Yan , Weimin Wang , Min Gao , Mingxuan Xiao

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Much of biomedical and healthcare data is encoded in discrete, symbolic form such as text and medical codes. There is a wealth of expert-curated biomedical domain knowledge stored in knowledge bases and ontologies, but the lack of reliable…

人工智能 · 计算机科学 2020-06-25 David Chang , Ivana Balazevic , Carl Allen , Daniel Chawla , Cynthia Brandt , Richard Andrew Taylor

In real-world clinical settings, data distributions evolve over time, with a continuous influx of new, limited disease cases. Therefore, class incremental learning is of great significance, i.e., deep learning models are required to learn…

计算机视觉与模式识别 · 计算机科学 2024-09-13 Yifei Yao , Hanrong Zhang

Accurate and explainable health event predictions are becoming crucial for healthcare providers to develop care plans for patients. The availability of electronic health records (EHR) has enabled machine learning advances in providing these…

机器学习 · 计算机科学 2021-05-18 Chang Lu , Chandan K. Reddy , Prithwish Chakraborty , Samantha Kleinberg , Yue Ning

This paper proposes a knowledge-enhanced disease diagnosis method based on a prompt learning framework. The method retrieves structured knowledge from external knowledge graphs related to clinical cases, encodes it, and injects it into the…

计算与语言 · 计算机科学 2024-09-17 Zhang Zheng

Motivation: Phenotype concept recognition (CR) is a fundamental task in biomedical text mining. However, existing methods either require ontology-specific training, making them struggle to generalize across diverse text styles and evolving…

计算与语言 · 计算机科学 2026-04-06 Yicheng Tao , Yuanhao Huang , Yiqun Wang , Xin Luo , Jie Liu

Diabetic retinopathy (DR) is a leading cause of vision loss worldwide, and early diagnosis through automated retinal image analysis can significantly reduce the risk of blindness. This paper presents a robust deep learning framework for…

计算机视觉与模式识别 · 计算机科学 2025-07-30 Faisal Ahmed