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Graph-based Retrieval-Augmented Generation (RAG) methods have significantly enhanced the performance of large language models (LLMs) in domain-specific tasks. However, existing RAG methods do not adequately utilize the naturally inherent…

计算与语言 · 计算机科学 2025-09-29 Haoyu Huang , Yongfeng Huang , Junjie Yang , Zhenyu Pan , Yongqiang Chen , Kaili Ma , Hongzhi Chen , James Cheng

Rare diseases affect hundreds of millions of people worldwide but are hard to detect since they have extremely low prevalence rates (varying from 1/1,000 to 1/200,000 patients) and are massively underdiagnosed. How do we reliably detect…

机器学习 · 计算机科学 2019-12-02 Limeng Cui , Siddharth Biswal , Lucas M. Glass , Greg Lever , Jimeng Sun , Cao Xiao

Large reasoning models (LRMs) have shown significant progress in test-time scaling through chain-of-thought prompting. Current approaches like search-o1 integrate retrieval augmented generation (RAG) into multi-step reasoning processes but…

计算与语言 · 计算机科学 2026-01-21 Kaiwen Wei , Rui Shan , Dongsheng Zou , Jianzhong Yang , Bi Zhao , Junnan Zhu , Jiang Zhong

Rare disease diagnosis requires matching variant-bearing genes to complex patient phenotypes across large and heterogeneous evidence sources. This process remains time-intensive in current clinical interpretation pipelines. To overcome…

基因组学 · 定量生物学 2026-03-09 Jaeyeon Lee , Lin Yao , Hyun-Hwan Jeong , Zhandong Liu

Large language models (LLMs) have significantly advanced the field of natural language generation. However, they frequently generate unverified outputs, which compromises their reliability in critical applications. In this study, we propose…

计算与语言 · 计算机科学 2025-02-18 Alexandru Lecu , Adrian Groza , Lezan Hawizy

Here we present a holistic approach for data exploration on dense knowledge graphs as a novel approach with a proof-of-concept in biomedical research. Knowledge graphs are increasingly becoming a vital factor in knowledge mining and…

人工智能 · 计算机科学 2019-12-16 Jens Dörpinghaus , Alexander Apke , Vanessa Lage-Rupprecht , Andreas Stefan

Retrieval-Augmented Generation (RAG) significantly improves the factuality of Large Language Models (LLMs), yet standard pipelines often lack mechanisms to verify inter- mediate reasoning, leaving them vulnerable to hallucinations in…

计算与语言 · 计算机科学 2026-03-12 Eeham Khan , Luis Rodriguez , Marc Queudot

We present SparseAttnNet, a new hierarchical attention-driven framework for efficient image classification that adaptively selects and processes only the most informative pixels from images. Traditional convolutional neural networks…

图像与视频处理 · 电气工程与系统科学 2025-05-13 Elad Yoshai , Dana Yagoda-Aharoni , Eden Dotan , Natan T. Shaked

Retrieval-Augmented Generation (RAG) enables large language models (LLMs) to access broader knowledge sources, yet factual inconsistencies persist due to noise in retrieved documents-even with advanced retrieval methods. We demonstrate that…

计算与语言 · 计算机科学 2025-06-04 Yongjian Li , HaoCheng Chu , Yukun Yan , Zhenghao Liu , Shi Yu , Zheni Zeng , Ruobing Wang , Sen Song , Zhiyuan Liu , Maosong Sun

We combine conditioning techniques with sparse grid quadrature rules to develop a computationally efficient method to approximate marginal, but not necessarily univariate, posterior quantities, yielding approximate Bayesian inference via…

统计计算 · 统计学 2019-04-17 Joshua Hewitt , Jennifer A. Hoeting

Recent studies in medical question answering (Medical QA) have actively explored the integration of large language models (LLMs) with biomedical knowledge graphs (KGs) to improve factual accuracy. However, most existing approaches still…

计算与语言 · 计算机科学 2026-01-15 Chaerin Lee , Sohee Park , Hyunsik Na , Daseon Choi

Routinely collected clinical blood tests are an emerging molecular data source for large-scale biomedical research but inherently feature irregular sampling and informative observation. Traditional approaches rely on imputation, which can…

定量方法 · 定量生物学 2025-03-20 Andrea Zerio , Maya Bechler-Speicher , Tine Jess , Aleksejs Sazonovs

This paper describes a novel hierarchical attention network for reading comprehension style question answering, which aims to answer questions for a given narrative paragraph. In the proposed method, attention and fusion are conducted…

计算与语言 · 计算机科学 2019-08-14 Wei Wang , Ming Yan , Chen Wu

With the development of deep convolutional neural networks, medical image segmentation has achieved a series of breakthroughs in recent years. However, the high-performance convolutional neural networks always mean numerous parameters and…

计算机视觉与模式识别 · 计算机科学 2022-08-30 Wenxuan Zou , Muyi Sun

In this paper, we investigate the retrieval-augmented generation (RAG) based on Knowledge Graphs (KGs) to improve the accuracy and reliability of Large Language Models (LLMs). Recent approaches suffer from insufficient and repetitive…

计算与语言 · 计算机科学 2024-04-22 Xinke Jiang , Ruizhe Zhang , Yongxin Xu , Rihong Qiu , Yue Fang , Zhiyuan Wang , Jinyi Tang , Hongxin Ding , Xu Chu , Junfeng Zhao , Yasha Wang

The integration of diverse clinical modalities such as medical imaging and the tabular data extracted from patients' Electronic Health Records (EHRs) is a crucial aspect of modern healthcare. Integrative analysis of multiple sources can…

计算机视觉与模式识别 · 计算机科学 2025-04-22 Daniel Duenias , Brennan Nichyporuk , Tal Arbel , Tammy Riklin Raviv

Informative gradients are often lost in large batch updates. We propose a robust mechanism to reinforce the sparse components within a random batch of data points. A finite queue of online gradients is used to determine their expected…

机器学习 · 计算机科学 2024-04-29 Irfan Mohammad Al Hasib

Motivation: Biomedical knowledge graphs (KGs) are crucial for drug discovery and disease understanding, yet their completion and reasoning are challenging. Knowledge Embedding (KE) methods capture global semantics but struggle with dynamic…

人工智能 · 计算机科学 2025-07-23 Yitong Lin , Jiaying He , Jiahe Chen , Xinnan Zhu , Jianwei Zheng , Tao Bo

The combination of machine learning (ML) and sparsity-promoting techniques is enabling direct extraction of governing equations from data, revolutionizing computational modeling in diverse fields of science and engineering. The discovered…

系统与控制 · 电气工程与系统科学 2026-05-12 Mohammad Amin Basiri , Sina Khanmohammadi

Intensive Care Units (ICU) require comprehensive patient data integration for enhanced clinical outcome predictions, crucial for assessing patient conditions. Recent deep learning advances have utilized patient time series data, and fusion…

机器学习 · 计算机科学 2023-11-14 Samyak Jain , Manuel Burger , Gunnar Rätsch , Rita Kuznetsova