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We study the problem of the self-assembly of nanoparticles (NPs) into finite mesoscopic structures with a programmed local morphology and complex overall shape. Our proposed building blocks are NPs directionally-functionalized with DNA. The…

软凝聚态物质 · 物理学 2013-11-04 Jonathan D. Halverson , Alexei V. Tkachenko

DNA is an ideal candidate to organize matter on the nanoscale, primarily due to the specificity and complexity of DNA based interactions. Recent advances in this direction include the self-assembly of colloidal crystals using DNA grafted…

软凝聚态物质 · 物理学 2009-11-13 Nicholas A. Licata , Alexei V. Tkachenko

Recent advancements in microbiology have motivated the study of the production of nanostructures with applications such as biomedical computing and molecular robotics. One way to construct these structures is to construct branched DNA…

DNA nanostructures with programmable shape and interactions can be used as building blocks for the self-assembly of crystalline materials with prescribed nanoscale features, holding a vast technological potential. Structural rigidity and…

软凝聚态物质 · 物理学 2019-01-30 Ryan A. Brady , William T. Kaufhold , Nicholas J. Brooks , Vito Foderà , Lorenzo Di Michele

The field of complex self-assembly is moving toward the design of multi-particle structures consisting of thousands of distinct building blocks. To exploit the potential benefits of structures with such `addressable complexity,' we need to…

软凝聚态物质 · 物理学 2015-06-02 William M. Jacobs , Aleks Reinhardt , Daan Frenkel

The design space for a self-assembled multicomponent objects ranges from a solution in which every building block is unique to one with the minimum number of distinct building blocks that unambiguously define the target structure. Using a…

软凝聚态物质 · 物理学 2023-03-13 Joakim Bohlin , Andrew J. Turberfield , Ard A. Louis , Petr Šulc

The development of novel strategies for self-assembly in the field of nanotechnology has witnessed remarkable progress in recent years. Here, we present a DNA-driven programmable self-assembly to fabricate the targeted nanophotonic…

光学 · 物理学 2023-07-21 Zeynep Senel , Ruby Phul , Ahmet Faruk Yazıcı , Akrema , Emirhan Taze , Talha Erdem

Experiments have reached a monumental capacity for designing and synthesizing microscopic particles for self-assembly, making it possible to precisely control particle concentrations, shapes, and interactions. However, more physical insight…

Molecular electronics and other technologies whose components comprise individual molecules have been pursued for half a century because the molecular scale represents the limit of miniaturisation of objects whose structure is tuneable for…

DNA nanotechnology uses predictable interactions of nucleic acids to precisely engineer complex nanostructures. Characterizing these self-assembled structures at the single-structure level is crucial for validating their design and…

生物物理 · 物理学 2025-10-21 Wangwei Dong , Zezhou Liu , Ruiyao Liu , Deborah Kuchnir Fygenson , Walter Reisner

The field of DNA nanotechnology has made it possible to assemble, with high yields, different structures that have actionable properties. For example, researchers have created components that can be actuated. An exciting next step is to…

机器学习 · 计算机科学 2021-02-01 Emma Benjaminson , Rebecca E. Taylor , Matthew Travers

Nearly thirty years after its inception, the field of DNA-programmed colloidal self-assembly has begun to realize its initial promise. In this review, we summarize recent developments in designing effective interactions and understanding…

软凝聚态物质 · 物理学 2025-05-08 William M. Jacobs , W. Benjamin Rogers

In recent years significant attention has been attracted to proposals which utilize DNA for nanotechnological applications. Potential applications of these ideas range from the programmable self-assembly of colloidal crystals, to biosensors…

软凝聚态物质 · 物理学 2008-05-02 Nicholas A. Licata

DNA-coated particles are promising as building blocks for functional and finite-sized assemblies because they can be programmed with orthogonal interactions owing to the sequence-specific hybridization of DNA strands. To fully exploit this…

软凝聚态物质 · 物理学 2026-04-17 T. C. M. Stevens , A. van der Sluis , I. K. Voets , P. G. Moerman

We introduce allostery-mimetic building blocks model for self-assembly of 3D structures. We represent the building blocks as patchy particles, where each binding site (patch) can be irreversibly activated or deactivated by binding of the…

计算物理 · 物理学 2024-03-19 Joshua Evans , Petr Šulc

Structural DNA nanotechnology has advanced to the extent that extremely complex structures can be designed. Much of this advancement has been due to the development of automated DNA design and simulation tools. Typically, the tools (e.g.…

生物大分子 · 定量生物学 2021-12-01 Durham Smith , Grigory Tikhomirov

The large-scale search for high-performing candidate 2D materials is limited to calculating a few simple descriptors, usually with first-principles density functional theory calculations. In this work, we alleviate this issue by extending…

材料科学 · 物理学 2020-07-07 Victor Venturi , Holden Parks , Zeeshan Ahmad , Venkatasubramanian Viswanathan

Autonomous materials discovery with desired properties is one of the ultimate goals for materials science, and the current studies have been focusing mostly on high-throughput screening based on density functional theory calculations and…

At the cutting edge of materials science, matter is designed to self-organize into structures that perform a wide range of functions. The past two decades have witnessed major innovations in the versatility of building blocks, ranging from…

软凝聚态物质 · 物理学 2022-09-26 Angus McMullen , Maitane Muñoz Basagoiti , Zorana Zeravcic , Jasna Brujic

Manufacturing of microstructures using a microfluidic device is a largely empirical effort due to the multi-physical nature of the fabrication process. As such, models are desired that will predict microstructure performance characteristics…

计算工程、金融与科学 · 计算机科学 2024-03-05 Nicholus R. Clinkinbeard , Reza Montazami , Nicole N. Hashemi
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