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In the field of lung cancer research, particularly in the analysis of overall survival (OS), artificial intelligence (AI) serves crucial roles with specific aims. Given the prevalent issue of missing data in the medical domain, our primary…

机器学习 · 计算机科学 2026-03-13 Camillo Maria Caruso , Valerio Guarrasi , Sara Ramella , Paolo Soda

In our study, we introduce a novel hybrid ensemble model that synergistically combines LSTM, BiLSTM, CNN, GRU, and GloVe embeddings for the classification of gene mutations in cancer. This model was rigorously tested using Kaggle's…

定量方法 · 定量生物学 2024-05-21 Sanad Aburass , Osama Dorgham , Jamil Al Shaqsi

AI computation in healthcare faces significant challenges when clinical datasets are limited and heterogeneous. Integrating datasets from multiple sources and different equipments is critical for effective AI computation but is complicated…

信号处理 · 电气工程与系统科学 2025-04-07 Baozhuo Su , Qingli Dou , Kang Liu , Zhengxian Qu , Jerry Deng , Ting Tan , Yanan Gu

Positron emission tomography (PET) combined with computed tomography (CT) imaging is routinely used in cancer diagnosis and prognosis by providing complementary information. Automatically segmenting tumors in PET/CT images can significantly…

图像与视频处理 · 电气工程与系统科学 2024-03-29 Jinpeng Lu , Jingyun Chen , Linghan Cai , Songhan Jiang , Yongbing Zhang

As large language models (LLMs) achieve strong performance on traditional benchmarks, there is an urgent need for more challenging evaluation frameworks that probe deeper aspects of semantic understanding. We introduce SAGE (Semantic…

人工智能 · 计算机科学 2025-09-26 Samarth Goel , Reagan J. Lee , Kannan Ramchandran

Morphological attributes from histopathological images and molecular profiles from genomic data are important information to drive diagnosis, prognosis, and therapy of cancers. By integrating these heterogeneous but complementary data, many…

机器学习 · 计算机科学 2022-02-28 Kaiwen Tan , Weixian Huang , Xiaofeng Liu , Jinlong Hu , Shoubin Dong

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

计算机视觉与模式识别 · 计算机科学 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

Traditional object detection methods face performance degradation challenges in complex scenarios such as low-light conditions and heavy occlusions due to a lack of high-level semantic understanding. To address this, this paper proposes an…

计算机视觉与模式识别 · 计算机科学 2025-09-25 Yunqing Hu , Zheming Yang , Chang Zhao , Wen Ji

In recent years, deep learning (DL) models have demonstrated remarkable achievements on non-trivial tasks such as speech recognition and natural language understanding. One of the significant contributors to its success is the proliferation…

机器学习 · 计算机科学 2022-12-13 Praveen Joshi , Mohammed Hasanuzzaman , Chandra Thapa , Haithem Afli , Ted Scully

There exists unexplained diverse variation within the predefined colon cancer stages using only features either from genomics or histopathological whole slide images as prognostic factors. Unraveling this variation will bring about improved…

定量方法 · 定量生物学 2022-12-15 Olalekan Ogundipe , Zeyneb Kurt , Wai Lok Woo

Accurate prediction of synthetic lethality (SL) is important for guiding the development of cancer drugs and therapies. SL prediction faces significant challenges in the effective fusion of heterogeneous multi-source data. Existing…

The variability in EEG signals between different individuals poses a significant challenge when implementing brain-computer interfaces (BCI). Commonly proposed solutions to this problem include deep learning models, due to their increased…

信号处理 · 电气工程与系统科学 2023-12-01 Stylianos Bakas , Siegfried Ludwig , Dimitrios A. Adamos , Nikolaos Laskaris , Yannis Panagakis , Stefanos Zafeiriou

The significant variability in cell size and shape continues to pose a major obstacle in computer-assisted cancer detection on gigapixel Whole Slide Images (WSIs), due to cellular heterogeneity. Current CNN-Transformer hybrids use static…

图像与视频处理 · 电气工程与系统科学 2026-03-24 Gia Huy Thai , Hoang-Nguyen Vu , Anh-Minh Phan , Quang-Thinh Ly , Tram Dinh , Thi-Ngoc-Truc Nguyen , Nhat Ho

The application of machine learning in medicine and healthcare has led to the creation of numerous diagnostic and prognostic models. However, despite their success, current approaches generally issue predictions using data from a single…

机器学习 · 计算机科学 2025-05-13 Fergus Imrie , Stefan Denner , Lucas S. Brunschwig , Klaus Maier-Hein , Mihaela van der Schaar

HONeYBEE (Harmonized ONcologY Biomedical Embedding Encoder) is an open-source framework that integrates multimodal biomedical data for oncology applications. It processes clinical data (structured and unstructured), whole-slide images,…

机器学习 · 计算机科学 2025-08-28 Aakash Tripathi , Asim Waqas , Matthew B. Schabath , Yasin Yilmaz , Ghulam Rasool

Accurate characterisation of visual attributes such as spiculation, lobulation, and calcification of lung nodules is critical in cancer management. The characterisation of these attributes is often subjective, which may lead to high inter-…

图像与视频处理 · 电气工程与系统科学 2022-06-13 Xiaohang Fu , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

Clinical risk prediction models often underperform in real-world settings due to poor calibration, limited transportability, and subgroup disparities. These challenges are amplified in high-dimensional multimodal cancer datasets…

机器学习 · 计算机科学 2026-02-26 Toktam Khatibi

Cancer survival prediction is important for developing personalized treatments and inducing disease-causing mechanisms. Multi-omics data integration is attracting widespread interest in cancer research for providing information for…

基因组学 · 定量生物学 2022-07-12 Xing Wu , Qiulian Fang

Multimodal Machine Learning offers a holistic view of a patient's status, integrating structured and unstructured data from electronic health records (EHR). We propose a framework to predict metastasis risk one month prior to diagnosis,…

机器学习 · 计算机科学 2026-04-01 Franco Rugolon , Korbinian Randl , Braslav Jovanovic , Ioanna Miliou , Panagiotis Papapetrou

Multimodal learning enhances the performance of various machine learning tasks by leveraging complementary information across different modalities. However, existing methods often learn multimodal representations that retain substantial…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Tong Zhang , Shu Shen , C. L. Philip Chen