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Cancer survival prediction is a challenging task that involves analyzing of the tumor microenvironment within Whole Slide Image (WSI). Previous methods cannot effectively capture the intricate interaction features among instances within the…

计算机视觉与模式识别 · 计算机科学 2024-10-23 Zekang Yang , Hong Liu , Xiangdong Wang

In machine learning and computer graphics, a fundamental task is the approximation of a probability density function through a well-dispersed collection of samples. Providing a formal metric for measuring the distance between probability…

图形学 · 计算机科学 2024-02-28 Baptiste Genest , Nicolas Courty , David Coeurjolly

Optimal Transport (OT) is a resource allocation problem with applications in biology, data science, economics and statistics, among others. In some of the applications, practitioners have access to samples which approximate the continuous…

Histopathology Whole-Slide Images (WSIs) provide an important tool to assess cancer prognosis in computational pathology (CPATH). While existing survival analysis (SA) approaches have made exciting progress, they are generally limited to…

计算机视觉与模式识别 · 计算机科学 2025-02-12 Pei Liu , Luping Ji , Jiaxiang Gou , Bo Fu , Mao Ye

In online incremental learning, data continuously arrives with substantial distributional shifts, creating a significant challenge because previous samples have limited replay value when learning a new task. Prior research has typically…

机器学习 · 计算机科学 2026-04-17 Quyen Tran , Hai Nguyen , Hoang Phan , Quan Dao , Linh Ngo , Khoat Than , Dinh Phung , Dimitris Metaxas , Trung Le

Optimal Transport (OT) problems are a cornerstone of many applications, but solving them is computationally expensive. To address this problem, we propose UNOT (Universal Neural Optimal Transport), a novel framework capable of accurately…

机器学习 · 计算机科学 2026-02-11 Jonathan Geuter , Gregor Kornhardt , Ingimar Tomasson , Vaios Laschos

The inherent safety alignment of Large Language Models (LLMs) is prone to erosion during fine-tuning, even when using seemingly innocuous datasets. While existing defenses attempt to mitigate this via data selection, they typically rely on…

机器学习 · 计算机科学 2026-01-13 Haozhong Wang , Zhuo Li , Yibo Yang , He Zhao , Hongyuan Zha , Dandan Guo

Histopathology is critical for the diagnosis of many diseases, including cancer. These protocols typically require pathologists to manually evaluate slides under a microscope, which is time-consuming and subjective, leading to interest in…

计算机视觉与模式识别 · 计算机科学 2023-03-07 Kianoush Falahkheirkhah , Alex Lu , David Alvarez-Melis , Grace Huynh

Root-mean-square deviation (RMSD) is widely used to assess structural similarity in systems ranging from flexible ligand conformers to complex molecular cluster configurations. Despite its wide utility, RMSD calculation is often challenged…

生物大分子 · 定量生物学 2025-09-03 Xiaoqi Wei , Xuhang Dai , Yaqi Wu , Yanxiang Zhao , Yingkai Zhang , Zixuan Cang

In this paper, we tackle the inductive semi-supervised learning problem that aims to obtain label predictions for out-of-sample data. The proposed approach, called Optimal Transport Induction (OTI), extends efficiently an optimal transport…

机器学习 · 统计学 2021-12-15 Mourad El Hamri , Younès Bennani , Issam Falih

Optimal transport (OT) is a widely used technique in machine learning, graphics, and vision that aligns two distributions or datasets using their relative geometry. In symmetry-rich settings, however, OT alignments based solely on pairwise…

机器学习 · 计算机科学 2025-09-26 Annabel Ma , Kaiying Hou , David Alvarez-Melis , Melanie Weber

This paper presents a novel two-step approach for the fundamental problem of learning an optimal map from one distribution to another. First, we learn an optimal transport (OT) plan, which can be thought as a one-to-many map between the two…

Optimal Transport (OT) has recently emerged as a powerful framework for learning minimal-displacement maps between distributions. The predominant approach involves a neural parametrization of the Monge formulation of OT, typically assuming…

机器学习 · 计算机科学 2024-07-23 Athina Sotiropoulou , David Alvarez-Melis

Recent studies have shown that Contrastive Language-Image Pre-training (CLIP) models are threatened by targeted data poisoning and backdoor attacks due to massive training image-caption pairs crawled from the Internet. Previous defense…

计算机视觉与模式识别 · 计算机科学 2025-09-24 Tong Zhang , Kuofeng Gao , Jiawang Bai , Leo Yu Zhang , Xin Yin , Zonghui Wang , Shouling Ji , Wenzhi Chen

Many machine learning systems make constrained decisions by optimizing factorized objectives, but the context-specific objective is often treated as fixed. We study contextual decision-weight learning: from logged decisions and proxy…

机器学习 · 计算机科学 2026-05-04 Renjun Hu , Hyun-Soo Ahn

Optimal Transport (OT) problem aims to find a transport plan that bridges two distributions while minimizing a given cost function. OT theory has been widely utilized in generative modeling. In the beginning, OT distance has been used as a…

机器学习 · 计算机科学 2024-03-08 Jaemoo Choi , Jaewoong Choi , Myungjoo Kang

While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable…

计算机视觉与模式识别 · 计算机科学 2025-11-12 Zhenfeng Zhuang , Fangyu Zhou , Liansheng Wang

Optimal transport aligns samples across distributions by minimizing the transportation cost between them, e.g., the geometric distances. Yet, it ignores coherence structure in the data such as clusters, does not handle outliers well, and…

机器学习 · 计算机科学 2023-05-31 Ching-Yao Chuang , Stefanie Jegelka , David Alvarez-Melis

The estimation of origin-destination (OD) matrices is a crucial aspect of Intelligent Transport Systems (ITS). It involves adjusting an initial OD matrix by regressing the current observations like traffic counts of road sections (e.g.,…

人工智能 · 计算机科学 2023-10-10 Zheli Xiong , Defu Lian , Enhong Chen , Gang Chen , Xiaomin Cheng

Recently, Neural Topic Models (NTMs) inspired by variational autoencoders have obtained increasingly research interest due to their promising results on text analysis. However, it is usually hard for existing NTMs to achieve good document…

信息检索 · 计算机科学 2022-06-01 He Zhao , Dinh Phung , Viet Huynh , Trung Le , Wray Buntine