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White matter hyperintensities (WMH) are radiological markers of small vessel disease and neurodegeneration, whose accurate segmentation and spatial localization are crucial for diagnosis and monitoring. While multimodal MRI offers…

图像与视频处理 · 电气工程与系统科学 2025-06-30 Julia Machnio , Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

In life sciences, the experts generally use empirical knowledge to recode variables, choose interactions and perform selection by classical approach. The aim of this work is to perform automatic learning algorithm for variables selection…

机器学习 · 统计学 2015-11-05 Bienvenue Kouwayè , Noël Fonton , Fabrice Rossi

Malaria is a serious infectious disease that is responsible for over half million deaths yearly worldwide. The major cause of these mortalities is late or inaccurate diagnosis. Manual microscopy is currently considered as the dominant…

机器学习 · 统计学 2017-08-18 Arash Mehrjou

Plasmodium spp. are the protozoan parasites responsible for malaria. Plasmodium spp. synthesise a biocrystal, hemozoin, which can be observed under cross-polarised light. These birefringent crystals can be seen due to different refractive…

医学物理 · 物理学 2023-04-28 Fraser Eadie , Matthew P Gibbins , Graham Gibson , Matthias Marti , Akhil Kallepalli

Malaria remains a major public health concern in Ethiopia, particularly in the Amhara Region, where seasonal and unpredictable transmission patterns make prevention and control challenging. Accurately forecasting malaria outbreaks is…

其他定量生物学 · 定量生物学 2025-10-03 Kassahun Azezew , Amsalu Tesema , Bitew Mekuria , Ayenew Kassie , Animut Embiale , Ayodeji Olalekan Salau , Tsega Asresa

Coarse-grain Lagrangian methods, such as Dissipative Particle Dynamics ( Hoogerbrugge et al., EPL, 1992), are suitable for describing mesoscopic fluid systems that include thermal fluctuations. However, the realistic simulation of liquids…

软凝聚态物质 · 物理学 2026-03-13 Giuseppe Colella , Allan D. Mackie , James P. Larentzos , Fernando Bresme , Josep Bonet Avalos

Multimodal imaging has shown great potential in cancer research by concurrently providing anatomical, functional, and molecular information in live, intact animals. During preclinical imaging of small animals like mice, anesthesia is…

医学物理 · 物理学 2024-10-11 Wenxuan Xue , Yuxuan Liang , Mengzhou Li , Shan Gao , Xavier R. Intes , Ge Wang

Randomness in optical systems emerges as a powerful resource for generating complex, non-deterministic light-matter interactions. In particular, random plasmonic metasurfaces harness nanoscale disorder to produce unique and irreproducible…

We establish a method, called pbFFS for photobleaching Fluctuation Fluorescence Spectroscopy, which aims at characterizing molecules or particles labelled with a unknown distribution or fluorophores. Using photobleaching as a control…

Molecular adhesion plays a central role in many biological systems, yet existing methods to quantify adhesive strength often struggle to bridge the gap between single-molecule resolution and biologically relevant environments. Here, we…

In situ polymerization and micropatterning of hydrogels on-chip opens the potential for many applications such as tracking and controlling the diffusion of molecules, stimulants, inhibitors, as well as nutrients and drugs, from their source…

Plasmonic hyperbolic metasurfaces have emerged as an effective platform for manipulating the propagation of light. Here, confined modes on arrays of silver nanoridges that exhibit hyperbolic dispersion are used to demonstrate and model a…

Here we report a random lasing based sensor which shows pH sensitivity exceeding by 2-orders of magnitude that of a conventional fluorescence sensor. We explain the sensing mechanism as related to gain modifications and lasing threshold…

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) affects 30-40% of US adults and is the most common chronic liver disease. Although often asymptomatic, progression can lead to cirrhosis. The objective of the…

Free-space electro-optic (EO) modulators operating at gigahertz and beyond are attractive for a wide range of emerging applications, including high-speed imaging, free-space optical communication, microwave photonics, and diffractive…

Effectively determining malaria parasitemia is a critical aspect in assisting clinicians to accurately determine the severity of the disease and provide quality treatment. Microscopy applied to thick smear blood smears is the de facto…

图像与视频处理 · 电气工程与系统科学 2020-12-04 Rose Nakasi , Aminah Zawedde , Ernest Mwebaze , Jeremy Francis Tusubira , Gilbert Maiga

There is today a growing need to accurately model the angular scattering response of metasurfaces for optical analog processing applications. However, the current metasurface modeling techniques are not well suited for such a task since…

光学 · 物理学 2023-01-04 Karim Achouri , Olivier J. F. Martin

This paper presents a comprehensive study on a novel multilayer surface plasmon resonance (SPR) biosensor designed for detecting trace-level toxins in liquid samples with exceptional precision and efficiency. Leveraging the Kretschmann…

系统与控制 · 电气工程与系统科学 2025-01-31 Suripto Bhuiyan , Michael Geller

Disaggregation modelling is a method of predicting disease risk at high resolution using aggregated response data. High resolution disease mapping is an important public health tool to aid the optimisation of resources, and is commonly used…

统计方法学 · 统计学 2023-04-18 Jack A. Hall , Tim C. D. Lucas

This study introduces a dual-band plasmonic absorber designed for simultaneous sensing applications in the near-infrared (NIR) and mid-infrared (MIR) regions. The absorber, composed of silver nanostructures on a metal plate with a…

光学 · 物理学 2024-11-20 Ayon Sarker , Sajid Muhaimin Choudhury