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Accurate simulations of the flow in the human airway are essential for advancing diagnostic methods. Many existing computational studies rely on simplified geometries or turbulence models, limiting their simulation's ability to resolve flow…

Inspiratory and expiratory flow in a multi-generation pig lung airway was numerically studied at a peak tracheal flow rate corresponding to a Reynolds number of 1150. The model was validated by comparing velocity distributions with previous…

流体动力学 · 物理学 2018-04-18 Peshala P. T Gamage , Fardin Khalili , Azad Md. K , Hansen A Mansy

The airflow in a subject-specific breathing human lung is simulated with a multiscale computational fluid dynamics (CFD) lung model. The three-dimensional (3D) airway geometry beginning from the mouth to about 7 generations of airways is…

流体动力学 · 物理学 2013-10-21 Jiwoong Choi , Youbing Yin , Eric A. Hoffman , Merryn H. Tawhai , Ching-Long Lin

Uniform fluid flow distribution in a symmetric volume can be realized through a symmetric branched tree. It is shown here, however, that the flow partitioning can be highly sensitive to deviations from exact symmetry if inertial effects are…

生物物理 · 物理学 2009-11-10 B. Mauroy , M. Filoche , J. S. Andrade , B. Sapoval

The seemingly simple process of inhalation relies on a complex interplay between muscular contraction in the thorax, elasto-capillary interactions in individual lung branches, propagation of air between different connected branches, and…

生物物理 · 物理学 2022-06-07 Jean-François Louf , Felix Kratz , Sujit S. Datta

We demonstrate flow rectification, valveless pumping or AC-to-DC conversion in macroscale fluidic networks with loops. Inspired by the unique anatomy of bird lungs and the phenomenon of directed airflow throughout the respiration cycle, we…

During a rapid inhalation, such as a sniff, the flow in the airways accelerates and decays quickly. The consequences for flow development and convective trans- port of an inhaled gas were investigated in a subject geometry extending from…

Computational fluid dynamics (CFD) simulations, in-vitro setups, and experimental ex-vivo approaches have been applied to numerous alveolar geometries over the past years. They aimed to study and examine airflow patterns, particle…

生物物理 · 物理学 2022-04-06 Isabella Francis , Suvash Saha

The tracheal flow field shapes particle transport into the lower airways and thus influences both the spread of inhaled pathogens and the effectiveness of aerosol-based therapies. Identifying how different inhalation routes modify the flow…

流体动力学 · 物理学 2026-02-18 Benedikt H. Johanning-Meiners , Luca Mayolle , Dominik Krug , Michael Klaas

We propose a one-way coupled model that tracks individual primary particles in a conceptually simple cellular flow setup to predict flocculation in turbulence. This computationally efficient model accounts for Stokes drag, lubrication,…

流体动力学 · 物理学 2020-04-22 K. Zhao , B. Vowinckel , T. -J. Hsu , T. Köllner , B. Bai , E. Meiburg

We study the bifurcations of the large scale jets in the turbulent regime of a forced shear flow using direct numerical simulations of the Navier-Stokes equations. The bifurcations are seen in the probability density function (PDF) of the…

流体动力学 · 物理学 2020-06-11 Vassilios Dallas , Kannabiran Seshasayanan , Stephan Fauve

Particle-laden turbulent flow that separates due to a bump inside a channel is simulated to analyse the effects of the Stokes number and the lift force on the particle spatial distribution. The fluid friction Reynolds number is…

Direct numerical simulations (DNS) and modal analysis techniques are applied to investigate the flow over a NACA-0012 airfoil at a Reynolds number of 50,000. Three different sweep angles are considered, namely 0, 20 and 40 degrees, for two…

流体动力学 · 物理学 2019-01-16 Nicola De Tullio , Neil D Sandham

Transonic buffet is an unsteady flow phenomenon that limits the safe flight envelope of modern aircraft. Scale-resolving simulations with span-periodic boundary conditions are capable of providing new insights into its flow physics. The…

流体动力学 · 物理学 2023-05-08 Markus Zauner , Pradeep Moise , Neil D. Sandham

Could the microdroplets formed by viscoelastic stretching and break-up of mucosal liquids in the upper respiratory tract (URT), when inhaled further downwind, explain the brisk pace at which deep lung infections emerge following onset of…

流体动力学 · 物理学 2025-04-29 Saikat Basu

The spatio-temporal dynamics of separation bubbles induced to form in a fully-developed turbulent boundary layer (with Reynolds number based on momentum thickness of the boundary layer of 490) over a flat plate are studied via direct…

流体动力学 · 物理学 2019-12-04 Wen Wu , Charles Meneveau , Rajat Mittal

Studies of flow through the human airway have shown that inhalation time (IT) and secondary flow structures can play important roles in particle deposition. However, the effects of varying IT in conjunction with respiratory rate (RR) on…

流体动力学 · 物理学 2021-01-26 Manikantam G. Gaddam , Arvind Santhanakrishnan

We study the primary bifurcations of a two-dimensional Kolmogorov flow in a channel subject to boundary conditions chosen to mimic a parallel flow, i.e. periodic and free-slip boundary conditions in the streamwise and spanwise directions,…

流体动力学 · 物理学 2020-04-28 Kannabiran Seshasayanan , Vassilios Dallas , Stephan Fauve

Trees are key roughness elements in urban environments, shaping airflow, microclimates, and pollutant dispersion. Yet the aerodynamic drag of complex tree-like structures at high Reynolds numbers remains poorly characterized compared with…

流体动力学 · 物理学 2026-03-31 T. Tokiwa , Y. Yin , R. Onishi

Chest physiotherapy is an empirical technique used to help secretions to get out of the lung whenever stagnation occurs. Although commonly used, little is known about the inner mechanisms of chest physiotherapy and controversies about its…

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