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Label-free cell classification is advantageous for supplying pristine cells for further use or examination, yet existing techniques frequently fall short in terms of specificity and speed. In this study, we address these limitations through…

图像与视频处理 · 电气工程与系统科学 2025-02-25 Khayrul Islam , Ratul Paul , Shen Wang , Yuwen Zhao , Partho Adhikary , Qiying Li , Xiaochen Qin , Yaling Liu

Label-free single-cell imaging offers a scalable, non-invasive alternative to fluorescence-based cytometry, yet inferring molecular phenotypes directly from bright-field morphology remains challenging. We present a unified Deep Learning…

计算机视觉与模式识别 · 计算机科学 2026-05-15 Saqib Nazir , Ardhendu Behera

Is self-supervised deep learning (DL) for medical image analysis already a serious alternative to the de facto standard of end-to-end trained supervised DL? We tackle this question for medical image classification, with a particular focus…

计算机视觉与模式识别 · 计算机科学 2023-09-08 Maximilian Nielsen , Laura Wenderoth , Thilo Sentker , René Werner

Recently, deep learning-based methods achieved promising performance in nuclei detection and classification applications. However, training deep learning-based methods requires a large amount of pixel-wise annotated data, which is…

图像与视频处理 · 电气工程与系统科学 2024-01-17 Nazanin Moradinasab , Rebecca A. Deaton , Laura S. Shankman , Gary K. Owens , Donald E. Brown

Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify…

计算机视觉与模式识别 · 计算机科学 2023-11-27 Stefan Röhrl , Johannes Groll , Manuel Lengl , Simon Schumann , Christian Klenk , Dominik Heim , Martin Knopp , Oliver Hayden , Klaus Diepold

The success of supervised deep learning models on cell recognition tasks relies on detailed annotations. Many previous works have managed to reduce the dependency on labels. However, considering the large number of cells contained in a…

计算机视觉与模式识别 · 计算机科学 2023-08-23 Pingyi Chen , Chenglu Zhu , Zhongyi Shui , Jiatong Cai , Sunyi Zheng , Shichuan Zhang , Lin Yang

Can a single label-free image reveal whether cancer cells were exposed to chemotherapy? We present an innovative methodology on the label-free and high-resolution imaging properties of phase holotomographic microscopy coupled with neural…

In-line with the success of deep learning on traditional recognition problem, several end-to-end deep models for zero-shot recognition have been proposed in the literature. These models are successful to predict a single unseen label given…

计算机视觉与模式识别 · 计算机科学 2018-03-19 Shafin Rahman , Salman Khan

Deep learning has significantly advanced medical imaging analysis (MIA), achieving state-of-the-art performance across diverse clinical tasks. However, its success largely depends on large-scale, high-quality labeled datasets, which are…

计算机视觉与模式识别 · 计算机科学 2025-05-09 Cheng Jin , Zhengrui Guo , Yi Lin , Luyang Luo , Hao Chen

Exposure to intense illumination light is an unavoidable consequence of fluorescence microscopy, and poses a risk to the health of the sample in every live-cell fluorescence microscopy experiment. Furthermore, the possible side-effects of…

计算机视觉与模式识别 · 计算机科学 2017-01-24 David Richmond , Anna Payne-Tobin Jost , Talley Lambert , Jennifer Waters , Hunter Elliott

Assessing the quality of bovine satellite cells (BSCs) is essential for the cultivated meat industry, which aims to address global food sustainability challenges. This study aims to develop a label-free method for predicting fluorescence…

计算机视觉与模式识别 · 计算机科学 2024-10-18 Sania Sinha , Aarham Wasit , Won Seob Kim , Jongkyoo Kim , Jiyoon Yi

In multi-label classification, the main focus has been to develop ways of learning the underlying dependencies between labels, and to take advantage of this at classification time. Developing better feature-space representations has been…

机器学习 · 计算机科学 2015-02-23 Jesse Read , Fernando Perez-Cruz

Label-Free Multiphoton Microscopy is a very powerful optical microscopy that can be applied to study samples with no need for exogenous fluorescent probes, keeping the main benefits of a Multiphoton approach, like longer penetration depths…

This work addresses the task of multilabel image classification. Inspired by the great success from deep convolutional neural networks (CNNs) for single-label visual-semantic embedding, we exploit extending these models for multilabel…

计算机视觉与模式识别 · 计算机科学 2021-01-28 Yi-Nan Li , Mei-Chen Yeh

Advancements in digital imaging technologies have sparked increased interest in using multiplexed immunofluorescence (mIF) images to visualise and identify the interactions between specific immunophenotypes with the tumour microenvironment…

图像与视频处理 · 电气工程与系统科学 2024-07-01 Piumi Sandarenu , Julia Chen , Iveta Slapetova , Lois Browne , Peter H. Graham , Alexander Swarbrick , Ewan K. A. Millar , Yang Song , Erik Meijering

Automated disease diagnosis using medical image analysis relies on deep learning, often requiring large labeled datasets for supervised model training. Diseases like Acute Myeloid Leukemia (AML) pose challenges due to scarce and costly…

计算机视觉与模式识别 · 计算机科学 2024-08-26 Salome Kazeminia , Max Joosten , Dragan Bosnacki , Carsten Marr

In life sciences, fluorescent labeling techniques are used to study molecular structures and interactions of cells. However, this type of cell imaging has its own limitations, one of which is that the process of staining the cells could be…

图像与视频处理 · 电气工程与系统科学 2020-05-07 Eunjae Kim

Accurate intraoperative assessment of glioma infiltration is essential for maximizing tumor resection while preserving functional brain tissue. Fluorescence lifetime imaging (FLIm) offers real-time, label-free biochemical contrast, but its…

计算机视觉与模式识别 · 计算机科学 2026-04-30 Silvia Noble Anbunesan , Mohamed Abul Hassan , Jinyi Qi , Lisanne Kraft , Han Sung Lee , Orin Bloch , Laura Marcu

Multi-label classification (MLC) problems are becoming increasingly popular in the context of medical imaging. This has in part been driven by the fact that acquiring annotations for MLC is far less burdensome than for semantic segmentation…

计算机视觉与模式识别 · 计算机科学 2019-07-11 Thomas Kurmann , Pablo Marquez Neila , Sebastian Wolf , Raphael Sznitman

We propose a selective learning method using meta-learning and deep reinforcement learning for medical image interpretation in the setting of limited labeling resources. Our method, MedSelect, consists of a trainable deep learning selector…

计算机视觉与模式识别 · 计算机科学 2021-03-29 Akshay Smit , Damir Vrabac , Yujie He , Andrew Y. Ng , Andrew L. Beam , Pranav Rajpurkar
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