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相关论文: Kolmogorov-Arnold Network for Gene Regulatory Netw…

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Graph neural networks (GNNs) excel in learning from network-like data but often lack interpretability, making their application challenging in domains requiring transparent decision-making. We propose the Graph Kolmogorov-Arnold Network…

机器学习 · 计算机科学 2025-06-02 Gianluca De Carlo , Andrea Mastropietro , Aris Anagnostopoulos

We introduce Graph Kolmogorov-Arnold Networks (GKAN), an innovative neural network architecture that extends the principles of the recently proposed Kolmogorov-Arnold Networks (KAN) to graph-structured data. By adopting the unique…

机器学习 · 计算机科学 2024-06-11 Mehrdad Kiamari , Mohammad Kiamari , Bhaskar Krishnamachari

Kolmogorov-Arnold Networks (KANs) have been recently proposed as a machine learning framework that is more interpretable and controllable than the multi-layer perceptron. Various network architectures have been proposed within the KAN…

机器学习 · 计算机科学 2025-02-21 Tatiana Boura , Stasinos Konstantopoulos

Gene Regulatory Network (GRN) inference is essential for understanding complex cellular mechanisms, rendered tractable through single-cell transcriptomic data. With the emergence of single-cell Foundation Models (scFMs), enhanced…

机器学习 · 计算机科学 2026-05-12 Jiaxin Qi , Hang Li , Yan Cui , Yuhua Zheng , Jianqiang Huang

This systematic review explores the theoretical foundations, evolution, applications, and future potential of Kolmogorov-Arnold Networks (KAN), a neural network model inspired by the Kolmogorov-Arnold representation theorem. KANs…

机器学习 · 计算机科学 2025-06-09 Shriyank Somvanshi , Syed Aaqib Javed , Md Monzurul Islam , Diwas Pandit , Subasish Das

Effective molecular representation learning is crucial for advancing molecular property prediction and drug design. Mainstream molecular representation learning approaches are based on Graph Neural Networks (GNNs). However, these approaches…

机器学习 · 计算机科学 2024-11-12 Ruifeng Li , Mingqian Li , Wei Liu , Hongyang Chen

Kolmogorov-Arnold Networks (KANs) are a recently introduced neural architecture that replace fixed nonlinearities with trainable activation functions, offering enhanced flexibility and interpretability. While KANs have been applied…

机器学习 · 计算机科学 2026-03-31 Spyros Rigas , Dhruv Verma , Georgios Alexandridis , Yixuan Wang

Accurately reconstructing Gene Regulatory Networks (GRNs) is crucial for understanding gene functions and disease mechanisms. Single-cell RNA sequencing (scRNA-seq) technology provides vast data for computational GRN reconstruction. Since…

分子网络 · 定量生物学 2025-12-16 Rijie Xi , Weikang Xu , Wei Xiong , Yuannong Ye , Bin Zhao

As key models in geometric deep learning, graph neural networks have demonstrated enormous power in molecular data analysis. Recently, a specially-designed learning scheme, known as Kolmogorov-Arnold Network (KAN), shows unique potential…

机器学习 · 计算机科学 2024-12-19 Longlong Li , Yipeng Zhang , Guanghui Wang , Kelin Xia

To address the issue of interpretability in multilayer perceptrons (MLPs), Kolmogorov-Arnold Networks (KANs) are introduced in 2024. However, optimizing KAN structures is labor-intensive, typically requiring manual intervention and…

神经与进化计算 · 计算机科学 2025-01-30 Quan Long , Bin Wang , Bing Xue , Mengjie Zhang

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that poses significant diagnostic challenges due to its complex etiology. Graph Convolutional Networks (GCNs) have shown promise in modeling brain connectivity for AD…

计算机视觉与模式识别 · 计算机科学 2025-04-02 Tianqi Ding , Dawei Xiang , Keith E Schubert , Liang Dong

Inferring gene regulatory networks (GRNs) from single-cell RNA sequencing (scRNA-seq) data is a complex challenge that requires capturing the intricate relationships between genes and their regulatory interactions. In this study, we tackle…

机器学习 · 计算机科学 2024-07-26 Sindhura Kommu , Yizhi Wang , Yue Wang , Xuan Wang

Kolmogorov-Arnold Networks (KANs) have recently emerged as a powerful alternative to traditional multilayer perceptrons. However, their reliance on predefined, bounded grids restricts their ability to approximate functions on unbounded…

机器学习 · 计算机科学 2025-10-10 Alireza Moradzadeh , Srimukh Prasad Veccham , Lukasz Wawrzyniak , Miles Macklin , Saee G. Paliwal

Gating mechanisms are ubiquitous, yet a complementary question in feed-forward networks remains under-explored: how to introduce frequency-rich expressivity without sacrificing stability and scalability? This tension is exposed by…

机器学习 · 计算机科学 2026-02-10 Jusheng Zhang , Yijia Fan , Kaitong Cai , Jing Yang , Yongsen Zheng , Kwok-Yan Lam , Liang Lin , Keze Wang

Kolmogorov-Arnold Networks (KAN) is a groundbreaking model recently proposed by the MIT team, representing a revolutionary approach with the potential to be a game-changer in the field. This innovative concept has rapidly garnered worldwide…

机器学习 · 计算机科学 2024-06-05 Kunpeng Xu , Lifei Chen , Shengrui Wang

Gene Regulatory Networks (GRNs) are intricate biological systems that control gene expression and regulation in response to environmental and developmental cues. Advances in computational biology, coupled with high throughput sequencing…

机器学习 · 计算机科学 2025-04-18 Akshata Hegde , Tom Nguyen , Jianlin Cheng

The integration of heterogeneous multi-omics datasets at a systems level remains a central challenge for developing analytical and computational models in precision cancer diagnostics. This paper introduces Multi-Omics Graph…

Unraveling the complexities of Gene Regulatory Networks (GRNs) is crucial for understanding cellular processes and disease mechanisms. Traditional computational methods often struggle with the dynamic nature of these networks. This study…

机器学习 · 计算机科学 2025-03-04 Hakan T. Otal , Abdulhamit Subasi , Furkan Kurt , M. Abdullah Canbaz , Yasin Uzun

While accurate, black-box system identification models lack interpretability of the underlying system dynamics. This paper proposes State-Space Kolmogorov-Arnold Networks (SS-KAN) to address this challenge by integrating Kolmogorov-Arnold…

机器学习 · 计算机科学 2025-06-24 Gonçalo Granjal Cruz , Balazs Renczes , Mark C Runacres , Jan Decuyper

Medical image segmentation demands models that achieve high accuracy while maintaining computational efficiency and clinical interpretability. While recent Kolmogorov-Arnold Networks (KANs) offer powerful adaptive non-linearities, their…

计算机视觉与模式识别 · 计算机科学 2026-04-15 Guojie Li , Tianyi Liu , Anwar P. P. Abdul Majeed , Muhammad Ateeq , Anh Nguyen , Fan Zhang
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