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Early detection of Alzheimer's Disease (AD) is greatly beneficial to AD patients, leading to early treatments that lessen symptoms and alleviating financial burden of health care. As one of the leading signs of AD, language capability…

计算与语言 · 计算机科学 2025-10-17 Yangyang Li

Fusing structural-functional images of the brain has shown great potential to analyze the deterioration of Alzheimer's disease (AD). However, it is a big challenge to effectively fuse the correlated and complementary information from…

图像与视频处理 · 电气工程与系统科学 2023-10-06 Qiankun Zuo , Junren Pan , Shuqiang Wang

\textbf{Objective:} Alzheimer's disease (AD) is the most prevalent form of dementia worldwide, encompassing a prodromal stage known as Mild Cognitive Impairment (MCI), where patients may either progress to AD or remain stable. The objective…

Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…

图像与视频处理 · 电气工程与系统科学 2021-11-16 Xin Zhang , Liangxiu Han , Wenyong Zhu , Liang Sun , Daoqiang Zhang

For effective treatment of Alzheimer disease (AD), it is important to identify subjects who are most likely to exhibit rapid cognitive decline. Herein, we developed a novel framework based on a deep convolutional neural network which can…

计算机视觉与模式识别 · 计算机科学 2017-04-21 Hongyoon Choi , Kyong Hwan Jin

Unveiling pathological brain changes associated with Alzheimer's disease (AD) is a challenging task especially that people do not show symptoms of dementia until it is late. Over the past years, neuroimaging techniques paved the way for…

定量方法 · 定量生物学 2018-08-07 Mayssa Soussia , Islem Rekik

The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer's disease (AD) is clinically relevant, and may above all have a significant impact on accelerate the development of new treatments. In this…

图像与视频处理 · 电气工程与系统科学 2019-07-16 Kilian Hett , Vinh-Thong Ta , José V. Manjón , Pierrick Coupé

Autism spectrum disorder (ASD) is a neurodevelopmental disorder which results in altered behavior, social development, and communication patterns. In past years, autism prevalence has tripled, with 1 in 54 children now affected. Given that…

Autism Spectrum Disorders (ASD) describe a heterogeneous set of conditions classified as neurodevelopmental disorders. Although the mechanisms underlying ASD are not yet fully understood, more recent literature focused on multiple genetics…

信号处理 · 电气工程与系统科学 2025-01-31 Jessica Vacca , Natascia Brondino , Fabio Dell'Acqua , Anna Vizziello , Pietro Savazzi

This paper presents a fully automated approach for identifying speech anomalies from voice recordings to aid in the assessment of speech impairments. By combining Connectionist Temporal Classification (CTC) and encoder-decoder-based…

声音 · 计算机科学 2023-08-04 Laurin Wagner , Mario Zusag , Theresa Bloder

Early diagnosis of Alzheimer's Disease (AD) faces multiple data-related challenges, including high variability in patient data, limited access to specialized diagnostic tests, and overreliance on single-type indicators. These challenges are…

定量方法 · 定量生物学 2025-03-05 Yizong Xing , Dhita Putri Pratama , Yuke Wang , Yufan Zhang , Brian E. Chapman

We propose an automatic detection method of Alzheimer's diseases using a gated convolutional neural network (GCNN) from speech data. This GCNN can be trained with a relatively small amount of data and can capture the temporal information in…

音频与语音处理 · 电气工程与系统科学 2018-04-02 Tifani Warnita , Nakamasa Inoue , Koichi Shinoda

In this paper, we propose a natural language processing architecture that can handle tasks that previously required two models as one model. With a single model, we analyze the language patterns and conversational context of Alzheimer's…

计算与语言 · 计算机科学 2022-11-16 Park Jun Yeong , Shin Su Jong , Choi Chang Hwan , Lee Jung Jae , Choi Sang-il

We present an approach to automatic detection of Alzheimer's type dementia based on characteristics of spontaneous spoken language dialogue consisting of interviews recorded in natural settings. The proposed method employs additive logistic…

音频与语音处理 · 电气工程与系统科学 2018-11-27 Saturnino Luz , Sofia de la Fuente , Pierre Albert

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer's disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

机器学习 · 计算机科学 2016-07-05 Ehsan Hosseini-Asl , Georgy Gimel'farb , Ayman El-Baz

Cognitive decline is a natural part of aging. However, under some circumstances, this decline is more pronounced than expected, typically due to disorders such as Alzheimer's disease. Early detection of an anomalous decline is crucial, as…

Alzheimer's disease (AD) is an irreversible neurode generative disease of the brain.The disease may causes memory loss, difficulty communicating and disorientation. For the diagnosis of Alzheimer's disease, a series of scales are often…

图像与视频处理 · 电气工程与系统科学 2022-01-13 Yelu Gao , Huang Huang , Lian Zhang

Idea Density (ID) measures the rate at which ideas or elementary predications are expressed in an utterance or in a text. Lower ID is found to be associated with an increased risk of developing Alzheimer's disease (AD) (Snowdon et al.,…

计算与语言 · 计算机科学 2017-06-15 Kairit Sirts , Olivier Piguet , Mark Johnson

Conversational speech often reveals early signs of cognitive decline, such as dementia and MCI. In the UK, one in four people belongs to an ethnic minority, and dementia prevalence is expected to rise most rapidly among Black and Asian…

Speech classification tasks often require powerful language understanding models to grasp useful features, which becomes problematic when limited training data is available. To attain superior classification performance, we propose to…

计算与语言 · 计算机科学 2024-07-26 Nicolae-Catalin Ristea , Andrei Anghel , Radu Tudor Ionescu