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Hypothesis: Bacterial contamination of surfaces poses a major threat to public health. Designing effective antibacterial or self-cleaning surfaces requires understanding how bacteria-laden droplets interact with solid substrates and how…

软凝聚态物质 · 物理学 2025-10-29 Sirshendu Misra , Sudip Shyam , Priyam Chakraborty , Sushanta K. Mitra

When treated with antibiotics below the minimum inhibitory concentration, bacterial cell division turns off, but cell growth does not. Thus, rod-like bacteria, including E. coli, can elongate many times their length without increasing their…

软凝聚态物质 · 物理学 2026-03-11 Richard Z. DeCurtis , Yongtae Ahn , Jane E. Hill , Sara M. Hashmi

Quantitative experiments are described on spatio-temporal patterns of coherent chemical signaling activity in populations of {\it Dictyostelium discoideum} amoebae. We observe competition between spontaneously firing centers and rotating…

凝聚态物理 · 物理学 2009-10-28 Kyoung J. Lee , Edward C. Cox , Raymond E. Goldstein

Active particles with their characteristic feature of self-propulsion are regarded as the simplest models for motility in living systems. The accumulation of active particles in low activity regions has led to the general belief that…

软凝聚态物质 · 物理学 2021-05-26 Hidde D. Vuijk , Holger Merlitz , Michael Lang , Abhinav Sharma , Jens-Uwe Sommer

The run-and-tumble dynamics of bacteria, as exhibited by \textit{E. coli}, offers a simple experimental realization of non-Brownian, yet diffusive, particles. Here we present some analytic and numerical results for models of the ideal…

统计力学 · 物理学 2009-08-12 J. Tailleur , M. E. Cates

Although the motility of the flagellated bacteria, Escherichia coli, has been widely studied, the effect of viscosity on swimming speed remains controversial. The swimming mode of wild-type E.coli is often idealized as a "run-and- tumble"…

生物物理 · 物理学 2018-05-09 Zijie Qu , Fatma Zeynep Temel , Rene Henderikx , Kenneth S. Breuer

We study chemotaxis of a single {\sl E.coli} bacterium in a medium where the nutrient chemical is also undergoing diffusion and its concentration has the form of a Gaussian whose width increases with time. We measure the average first…

细胞行为 · 定量生物学 2015-04-30 Subrata Dev , Sakuntala Chatterjee

An active chiral rotor is a spherical object that can generate chiral flows in a fluid by rotating about an axis. For example, if the flow around the upper hemisphere of the chiral rotor is in a clockwise direction, then the flow in the…

软凝聚态物质 · 物理学 2025-01-29 R. Maity , Snigdha Thakur , P. S. Burada

Eukaryotic cells are able to sense chemical gradients in a wide range of environments. We show that, if a cell is exposed to a highly variable environment, it may gain chemotactic accuracy by expressing multiple receptor types with varying…

细胞行为 · 定量生物学 2020-11-04 Austin Hopkins , Brian A. Camley

Collective cell migration contributes to embryogenesis, wound healing and tumor metastasis. Cell monolayer migration experiments help understanding what determines the movement of cells far from the leading edge. Inhibiting cell…

生物物理 · 物理学 2018-03-26 S. Tlili , E. Gauquelin , B. Li , O. Cardoso , B. Ladoux , H. Delanoë-Ayari , F. Graner

The chemotactic network of Escherichia coli has been studied extensively both biophysically and information-theoretically. Nevertheless, the connection between these two aspects is still elusive. In this work, we report such a connection by…

细胞行为 · 定量生物学 2021-03-31 Kento Nakamura , Tetsuya J. Kobayashi

We demonstrate that active rotations in chemically signalling particles, such as autochemotactic {\it E. coli} close to walls, create a route for pattern formation based on a nonlinear yet deterministic instability mechanism. For slow…

软凝聚态物质 · 物理学 2016-08-19 Benno Liebchen , Michael E. Cates , Davide Marenduzzo

Motivated by the observation of non-exponential run-time distributions of bacterial swimmers, we propose a minimal phenomenological model for taxis of active particles whose motion is controlled by an internal clock. The ticking of the…

生物物理 · 物理学 2020-07-23 Luis Gómez Nava , Robert Großmann , Marius Hintsche , Carsten Beta , Fernando Peruani

Microswimmers such as E. Coli bacteria accumulate and exhibit an intriguing dynamics near walls, governed by hydrodynamic and steric interactions. Insight into the underlying mechanisms and predominant interactions demand a detailed…

软凝聚态物质 · 物理学 2020-07-03 S. Mahdiyeh Mousavi , Gerhard Gompper , Roland G. Winkler

The collective chemotaxis of multicellular clusters is an important phenomenon in various physiological contexts, ranging from embryonic development to cancer metastasis. Such clusters often display interesting shape dynamics and…

组织与器官 · 定量生物学 2025-06-03 Monika Sanoria , Gema Malet-Engra , Giorgio Scita , Nir Gov , Ajay Gopinathan

A novel trait-structured Keller-Segel model that explores the dynamics of a migrating cell population guided by chemotaxis in response to an external ligand concentration is derived and analysed. Unlike traditional Keller-Segel models, this…

细胞行为 · 定量生物学 2025-02-27 Viktoria Freingruber , Tommaso Lorenzi , Kevin J. Painter , Mariya Ptashnyk

For navigation, microscopic agents such as biological cells rely on noisy sensory input. In cells performing chemotaxis, such noise arises from the stochastic binding of signaling molecules at low concentrations. Using chemotaxis of sperm…

Experiments have recently shown the feasibility of utilising bacteria as micro-scale robotic devices, with special attention paid to the development of bacteria-driven micro-swimmers taking advantage of built-in actuation and sensing…

软凝聚态物质 · 物理学 2019-02-14 Christian Esparza Lopez , Albane Thery , Eric Lauga

Various microorganisms and some mammalian cells are able to swim in viscous fluids by performing nonreciprocal body deformations, such as rotating attached flagella or by distorting their entire body. In order to perform chemotaxis, i.e. to…

生物物理 · 物理学 2021-05-06 Benedikt Hartl , Maximilian Hübl , Gerhard Kahl , Andreas Zöttl

Many fascinating properties of biological active matter crucially depend on the capacity of constituting entities to perform directed motion, e.g., molecular motors transporting vesicles inside cells or bacteria searching for food. While…

统计力学 · 物理学 2023-06-21 Pietro Luigi Muzzeddu , Édgar Roldán , Andrea Gambassi , Abhinav Sharma