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Machine learning methods usually depend on internal parameters -- so called hyperparameters -- that need to be optimized for best performance. Such optimization poses a burden on machine learning practitioners, requiring expert knowledge,…

化学物理 · 物理学 2020-04-03 Annika Stuke , Patrick Rinke , Milica Todorović

Nested error regression models are useful tools for analysis of grouped data, especially in the case of small area estimation. This paper suggests a nested error regression model using uncertain random effects in which the random effect in…

统计方法学 · 统计学 2017-02-28 Shonosuke Sugasawa , Tatsuya Kubokawa

Statistical inference for high-dimensional regression heteroskedasticity is an important but under-explored problem. The current paper aims at filling this gap by proposing two tests, namely the variance difference test and the variance…

统计方法学 · 统计学 2022-12-06 Chi Chien-Ming

A typical problem in air pollution epidemiology is exposure assessment for individuals for which health data are available. Due to the sparsity of monitoring sites and the limited temporal frequency with which measurements of air pollutants…

Interactions between genes and environmental factors may play a key role in the etiology of many common disorders. Several regularized generalized linear models (GLMs) have been proposed for hierarchical selection of gene by environment…

统计方法学 · 统计学 2023-12-22 Julien St-Pierre , Karim Oualkacha , Julien St-Pierre

We study a nonparametric approach to Bayesian computation via feature means, where the expectation of prior features is updated to yield expected kernel posterior features, based on regression from learned neural net or kernel features of…

机器学习 · 统计学 2022-08-11 Liyuan Xu , Yutian Chen , Arnaud Doucet , Arthur Gretton

Whole genome sequencing (WGS) is quickly becoming the customary means for identification of antimicrobial resistance (AMR) due to its ability to obtain high resolution information about the genes and mechanisms that are causing resistance…

基因组学 · 定量生物学 2021-07-27 Mattia Prosperi , Simone Marini , Christina Boucher , Jiang Bian

In prognostics and health management (PHM) of engineered systems, maintenance decisions are ideally informed by predictions of a system's remaining useful life (RUL) based on operational data. Model-based prognostics algorithms rely on a…

统计方法学 · 统计学 2026-01-23 Xinyu Jia , Iason Papaioannou , Daniel Straub

Many applications involve estimating the mean of multiple binomial outcomes as a common problem -- assessing intergenerational mobility of census tracts, estimating prevalence of infectious diseases across countries, and measuring…

计量经济学 · 经济学 2026-01-01 Yan Chen , Lihua Lei

The health impact of long-term exposure to air pollution is now routinely estimated using spatial ecological studies, due to the recent widespread availability of spatial referenced pollution and disease data. However, this areal unit study…

应用统计 · 统计学 2014-12-16 Duncan Lee , Christophe Sarran

The Hierarchical Mixture of Experts (HME) is a well-known tree-based model for regression and classification, based on soft probabilistic splits. In its original formulation it was trained by maximum likelihood, and is therefore prone to…

机器学习 · 计算机科学 2012-12-12 Christopher M. Bishop , Markus Svensen

Exposure mixtures frequently occur in data across many domains, particularly in the fields of environmental and nutritional epidemiology. Various strategies have arisen to answer questions about mixtures, including methods such as weighted…

The Bayes Error Rate (BER) is the fundamental limit on the achievable generalizable classification accuracy of any machine learning model due to inherent uncertainty within the data. BER estimators offer insight into the difficulty of any…

机器学习 · 计算机科学 2025-09-24 Lesley Wheat , Martin v. Mohrenschildt , Saeid Habibi

Restricted mean survival time (RMST) is an intuitive summary statistic for time-to-event random variables, and can be used for measuring treatment effects. Compared to hazard ratio, its estimation procedure is robust against the…

统计方法学 · 统计学 2023-05-25 Ruizhe Chen , Sanjib Basu , Qian Shi

We propose a voxel-wise general linear model with autoregressive noise and heteroscedastic noise innovations (GLMH) for analyzing functional magnetic resonance imaging (fMRI) data. The model is analyzed from a Bayesian perspective and has…

应用统计 · 统计学 2017-05-31 Anders Eklund , Martin A. Lindquist , Mattias Villani

Towards understanding the fundamental limits of estimation from data of varied quality, we study the problem of estimating a mean parameter from heteroskedastic Gaussian observations where the variances are unknown and may vary arbitrarily…

统计理论 · 数学 2026-03-17 Yanjun Han , Abhishek Shetty , Jacob Shkrob

Public health researchers often estimate health effects of exposures (e.g., pollution, diet, lifestyle) that cannot be directly measured for study subjects. A common strategy in environmental epidemiology is to use a first-stage (exposure)…

统计方法学 · 统计学 2014-06-03 Adam A. Szpiro , Christopher J. Paciorek

We propose a vector-valued regression problem whose solution is equivalent to the reproducing kernel Hilbert space (RKHS) embedding of the Bayesian posterior distribution. This equivalence provides a new understanding of kernel Bayesian…

机器学习 · 统计学 2016-10-27 Yang Song , Jun Zhu , Yong Ren

In microbiome studies, it is often of great interest to identify clusters or partitions of microbiome profiles within a study population and to characterize the distinctive attributes of each resulting microbial community. While raw counts…

统计方法学 · 统计学 2025-08-18 Zhongmao Liu , Xiaohui Yin , Yanjiao Zhou , Gen Li , Kun Chen

In variety testing, multi-environment trials (MET) are essential for evaluating the genotypic performance of crop plants. A persistent challenge in the statistical analysis of MET data is the estimation of variance components, which are…

统计方法学 · 统计学 2026-04-20 Stephan Bark , Waqas Ahmed Malik , Maryna Prus , Hans-Peter Piepho , Volker Schmid