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Automated experiments in scanning transmission electron microscopy (STEM) require rapid image segmentation to optimize data representation for human interpretation, decision-making, site-selective spectroscopies, and atomic manipulation.…

Modern automated microscopy faces a fundamental discovery challenge: in many systems, the most important scientific information does not reside in the immediately visible image features, but in the target space of sequentially acquired…

Society's capacity for algorithmic problem-solving has never been greater. Artificial Intelligence is now applied across more domains than ever, a consequence of powerful abstractions, abundant data, and accessible software. As capabilities…

机器学习 · 统计学 2024-08-20 Kris Sankaran

Ultrasound (US) has the unique potential to offer access to medical imaging to anyone, everywhere. Devices have become ultra-portable and cost-effective, akin to the stethoscope. Nevertheless US image quality and diagnostic efficacy are…

信号处理 · 电气工程与系统科学 2024-10-18 Ruud JG van Sloun

Many Artificial Intelligence systems depend on the agent's updating its beliefs about the world on the basis of experience. Experiments constitute one type of experience, so scientific methodology offers a natural environment for examining…

人工智能 · 计算机科学 2013-04-08 Harold P. Lehmann

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

计算与语言 · 计算机科学 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn

Live-cell imaging of multiple subcellular structures is essential for understanding subcellular dynamics. However, the conventional multi-color sequential fluorescence microscopy suffers from significant imaging delays and limited number of…

亚细胞过程 · 定量生物学 2025-01-13 Mingyang Chen , Luhong Jin , Xuwei Xuan , Defu Yang , Yun Cheng , Ju Zhang

We present a novel method for quantifying the microscopic structure of brain tissue. It is based on the automated recognition of interpretable features obtained by analyzing the shapes of cells. This contrasts with prevailing methods of…

计算机视觉与模式识别 · 计算机科学 2024-04-10 Kui Qian , Litao Qiao , Beth Friedman , Edward O'Donnell , David Kleinfeld , Yoav Freund

The rapid evolution of artificial intelligence has led to expectations of transformative impact on science, yet current systems remain fundamentally limited in enabling genuine scientific discovery. This perspective contends that progress…

人工智能 · 计算机科学 2025-12-16 Karthik Duraisamy

Reproducibility remains a central challenge in machine learning (ML), especially in collaborative eScience projects where teams iterate over data, features, and models. Current ML workflows are often dynamic yet fragmented, relying on…

机器学习 · 计算机科学 2025-06-23 Zhiwei Li , Carl Kesselman , Tran Huy Nguyen , Benjamin Yixing Xu , Kyle Bolo , Kimberley Yu

Segmentation, or the outlining of objects within images, is a critical step in the measurement and analysis of cells within microscopy images. While improvements continue to be made in tools that rely on classical methods for segmentation,…

定量方法 · 定量生物学 2024-03-15 Nodar Gogoberidze , Beth A. Cimini

Recent advances in agentic AI have led to systems capable of autonomous task execution and language-based reasoning, yet their spatial reasoning abilities remain limited and underexplored, largely constrained to symbolic and sequential…

Machine learning and artificial intelligence (ML/AI) are rapidly becoming an indispensable part of physics research, with domain applications ranging from theory and materials prediction to high-throughput data analysis. In parallel, the…

Modern scientific discovery increasingly requires coordinating distributed facilities and heterogeneous resources, forcing researchers to act as manual workflow coordinators rather than scientists. Advances in AI leading to AI agents show…

Medical image classification is a critical problem for healthcare, with the potential to alleviate the workload of doctors and facilitate diagnoses of patients. However, two challenges arise when deploying deep learning models to real-world…

计算机视觉与模式识别 · 计算机科学 2023-10-06 An Yan , Yu Wang , Yiwu Zhong , Zexue He , Petros Karypis , Zihan Wang , Chengyu Dong , Amilcare Gentili , Chun-Nan Hsu , Jingbo Shang , Julian McAuley

There are two things to be considered when we evaluate predictive models. One is prediction accuracy,and the other is interpretability. Over the recent decades, many prediction models of high performance, such as ensemble-based models and…

机器学习 · 统计学 2024-08-05 Yongchan Choi , Seokhun Park , Chanmoo Park , Dongha Kim , Yongdai Kim

Data subsampling has become widely recognized as a tool to overcome computational and economic bottlenecks in analyzing massive datasets. We contribute to the development of adaptive design for estimation of finite population…

统计方法学 · 统计学 2024-07-08 Henrik Imberg , Xiaomi Yang , Carol Flannagan , Jonas Bärgman

A key challenge in artificial intelligence is the creation of systems capable of autonomously advancing scientific understanding by exploring novel domains, identifying complex patterns, and uncovering previously unseen connections in vast…

人工智能 · 计算机科学 2024-09-10 Alireza Ghafarollahi , Markus J. Buehler

In this position paper, we present ideas about creating a next generation framework towards an adaptive interface for data communication and visualisation systems. Our objective is to develop a system that accepts large data sets as inputs…

人机交互 · 计算机科学 2016-11-15 Grazziela P. Figueredo , Christian Wagner , Jonathan M. Garibaldi , Uwe Aickelin

This paper aims at identifying emerging computational intelligence trends for the design and modeling of complex biometric-enabled infrastructure and systems. Biometric-enabled systems are evolving towards deep learning and deep inference…

计算机视觉与模式识别 · 计算机科学 2020-06-23 Svetlana Yanushkevich , Shawn Eastwood , Kenneth Lai , Vlad Shmerko